Gene Expression Literature Summary

• Symbol: Kcnq2
• Name: potassium voltage-gated channel, subfamily Q, member 2
• ID: MGI:1309503

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E11	E11.5	E14.5	E15	E16.5	E17	E17.5	E18	E18.5	P
In situ RNA (section)											1
In situ reporter (knock in)											1
Northern blot	1	1			1		1			1	1
Western blot										1	1
RT-PCR			1	1		1		1	1		8
cDNA clones											1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Kcnq2  potassium voltage-gated channel, subfamily Q, member 2   (Synonyms: KQT2, Nmf134)
Results	Reference
2*	J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
1	J:181631 Gehman LT, Meera P, Stoilov P, Shiue L, O'Brien JE, Meisler MH, Ares M Jr, Otis TS, Black DL, The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function. Genes Dev. 2012 Mar 1;26(5):445-60
2*	J:119550 Harrell MD, Harbi S, Hoffman JF, Zavadil J, Coetzee WA, Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. Physiol Genomics. 2007 Feb 12;28(3):273-83
1	J:232973 Hirst CS, Foong JP, Stamp LA, Fegan E, Dent S, Cooper EC, Lomax AE, Anderson CR, Bornstein JC, Young HM, McKeown SJ, Ion channel expression in the developing enteric nervous system. PLoS One. 2015;10(3):e0123436
1	J:294282 Li L, Ruan X, Wen C, Chen P, Liu W, Zhu L, Xiang P, Zhang X, Wei Q, Hou L, Yin B, Yuan J, Qiang B, Shu P, Peng X, The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019 Jul 16;28(3):698-711.e5
2	J:207976 Li Q, Zheng S, Han A, Lin CH, Stoilov P, Fu XD, Black DL, The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation. Elife. 2014;3:e01201
7	J:49031 Nakamura M, Watanabe H, Kubo Y, Yokoyama M, Matsumoto T, Sasai H, Nishi Y, KQT2, a new putative potassium channel family produced by alternative splicing. Isolation, genomic structure, and alternative splicing of the putative potassium channels. Receptors Channels. 1998;5(5):255-71
1*	J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966
1*	J:281311 Nakano Y, Wiechert S, Banfi B, Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019 Apr 16;27(3):860-871.e8
3	J:340358 Oh H, Lee S, Oh Y, Kim S, Kim YS, Yang Y, Choi W, Yoo YE, Cho H, Lee S, Yang E, Koh W, Won W, Kim R, Lee CJ, Kim H, Kang H, Kim JY, Ku T, Paik SB, Kim E, Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice. Nat Commun. 2023 Jun 15;14(1):3547
2*	J:62797 Watanabe H, Nagata E, Kosakai A, Nakamura M, Yokoyama M, Tanaka K, Sasai H, Disruption of the epilepsy KCNQ2 gene results in neural hyperexcitability. J Neurochem. 2000 Jul;75(1):28-33
1*	J:82964 Yang Y, Beyer BJ, Otto JF, O'Brien TP, Letts VA, White HS, Frankel WN, Spontaneous deletion of epilepsy gene orthologs in a mutant mouse with a low electroconvulsive threshold. Hum Mol Genet. 2003 May 1;12(9):975-84