Symbol Name ID |
Sptbn2
spectrin beta, non-erythrocytic 2 MGI:1313261 |
Age | E10.5 | E13.5 | E16.5 | E17.5 | E18.5 | E | P |
Immunohistochemistry (section) | 1 | 1 | 1 | 2 | 1 | 5 | |
Immunohistochemistry (whole mount) | 1 | 1 | 2 | 4 | |||
In situ reporter (knock in) | 1 | ||||||
Western blot | 1 | ||||||
RT-PCR | 1 | 2 |
Sptbn2 spectrin beta, non-erythrocytic 2 (Synonyms: Spnb3) | |
Results | Reference |
2 | J:240403 Duncan JS, Stoller ML, Francl AF, Tissir F, Devenport D, Deans MR, Celsr1 coordinates the planar polarity of vestibular hair cells during inner ear development. Dev Biol. 2017 Mar 15;423(2):126-137 |
2 | J:348705 Goodrich EJ, Deans MR, Emx2 lineage tracing reveals antecedent patterns of planar polarity in the mouse inner ear. Development. 2024 May 15;151(10):dev202425 |
1 | J:330450 Ji YR, Tona Y, Wafa T, Christman ME, Tourney ED, Jiang T, Ohta S, Cheng H, Fitzgerald T, Fritzsch B, Jones SM, Cullen KE, Wu DK, Function of bidirectional sensitivity in the otolith organs established by transcription factor Emx2. Nat Commun. 2022 Oct 24;13(1):6330 |
1 | J:253478 Jiang T, Kindt K, Wu DK, Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells. Elife. 2017 Mar 7;6:e23661 |
1 | J:314906 Khang R, Jo A, Kang H, Kim H, Kwag E, Lee JY, Koo O, Park J, Kim HK, Jo DG, Hwang I, Ahn JY, Lee Y, Choi JY, Lee YS, Shin JH, Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation. Sci Rep. 2021 Nov 23;11(1):22745 |
1 | J:306060 Kindt KS, Akturk A, Jarysta A, Day M, Beirl A, Flonard M, Tarchini B, EMX2-GPR156-Galphai reverses hair cell orientation in mechanosensory epithelia. Nat Commun. 2021 May 17;12(1):2861 |
1 | J:336512 Knapp L, Sun H, Wang YM, Chen BJ, Lin X, Gao N, Chen P, Ren D, Rab11a Is Essential for the Development and Integrity of the Stereocilia and Kinocilia in the Mammalian Organ of Corti. eNeuro. 2023 Jun;10(6):ENEURO.0420-22.2023 |
1* | J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9 |
2* | J:214712 Le Bras B, Freal A, Czarnecki A, Legendre P, Bullier E, Komada M, Brophy PJ, Davenne M, Couraud F, In vivo assembly of the axon initial segment in motor neurons. Brain Struct Funct. 2014 Jul;219(4):1433-50 |
2 | J:142574 Legendre K, Safieddine S, Kussel-Andermann P, Petit C, El-Amraoui A, alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells. J Cell Sci. 2008 Oct 15;121(Pt 20):3347-56 |
1 | J:217667 May-Simera HL, Petralia RS, Montcouquiol M, Wang YX, Szarama KB, Liu Y, Lin W, Deans MR, Pazour GJ, Kelley MW, Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochlea. Development. 2015 Feb 1;142(3):555-66 |
1 | J:294163 Ono K, Sandell LL, Trainor PA, Wu DK, Retinoic acid synthesis and autoregulation mediate zonal patterning of vestibular organs and inner ear morphogenesis. Development. 2020 Aug 7;147(15):dev192070 |
1 | J:270142 Rasiah PK, Maddala R, Bennett V, Rao PV, Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth. Dev Biol. 2019 Feb 1;446(1):119-131 |
3 | J:186305 Stankewich MC, Cianci CD, Stabach PR, Ji L, Nath A, Morrow JS, Cell organization, growth, and neural and cardiac development require alphaII-spectrin. J Cell Sci. 2011 Dec 1;124(Pt 23):3956-66 |
2 | J:349011 Stansak KL, Baum LD, Ghosh S, Thapa P, Vanga V, Walters BJ, PCP auto count: a novel Fiji/ImageJ plug-in for automated quantification of planar cell polarity and cell counting. Front Cell Dev Biol. 2024;12:1394031 |
2 | J:261565 Stoller ML, Roman O Jr., Deans MR, Domineering non-autonomy in Vangl1;Vangl2 double mutants demonstrates intercellular PCP signaling in the vertebrate inner ear. Dev Biol. 2018 May 1;437(1):17-26 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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