Gene Expression Literature Summary

• Symbol: Tnfrsf11a
• Name: tumor necrosis factor receptor superfamily, member 11a, NFKB activator
• ID: MGI:1314891

18 matching records from 18 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E11.5	E12	E12.5	E13.5	E14	E14.5	E15	E15.5	E16.5	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)				1				1		1	1			1
In situ RNA (section)	1		3	3		2		1					1	2
In situ RNA (whole mount)								1
In situ reporter (knock in)				1		1		1		1
RT-PCR	1	1	1	2	1	2	1	2	1	1	2	1		7
cDNA clones				1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tnfrsf11a  tumor necrosis factor receptor superfamily, member 11a, NFKB activator   (Synonyms: Rank, TRANCE-R)
Results	Reference
1*	J:129388 Aioub M, Lezot F, Molla M, Castaneda B, Robert B, Goubin G, Nefussi JR, Berdal A, Msx2 -/- transgenic mice develop compound amelogenesis imperfecta, dentinogenesis imperfecta and periodental osteopetrosis. Bone. 2007 Nov;41(5):851-9
4	J:236470 Akiyama N, Takizawa N, Miyauchi M, Yanai H, Tateishi R, Shinzawa M, Yoshinaga R, Kurihara M, Demizu Y, Yasuda H, Yagi S, Wu G, Matsumoto M, Sakamoto R, Yoshida N, Penninger JM, Kobayashi Y, Inoue J, Akiyama T, Identification of embryonic precursor cells that differentiate into thymic epithelial cells expressing autoimmune regulator. J Exp Med. 2016 Jul 25;213(8):1441-58
5	J:139649 Akiyama T, Shimo Y, Yanai H, Qin J, Ohshima D, Maruyama Y, Asaumi Y, Kitazawa J, Takayanagi H, Penninger JM, Matsumoto M, Nitta T, Takahama Y, Inoue J, The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance. Immunity. 2008 Sep;29(3):423-37
1	J:171274 Combs MD, Braitsch CM, Lange AW, James JF, Yutzey KE, NFATC1 promotes epicardium-derived cell invasion into myocardium. Development. 2011 May;138(9):1747-57
1*	J:288988 Coudert AE, Redelsperger F, Chabbi-Achengli Y, Vernochet C, Marty C, Decrouy X, Heidmann T, de Vernejoul MC, Dupressoir A, Role of the captured retroviral envelope syncytin-B gene in the fusion of osteoclast and giant cell precursors and in bone resorption, analyzed ex vivo and in vivo in syncytin-B knockout mice. Bone Rep. 2019 Dec;11:100214
1	J:316298 Dejaeger M, Bohm AM, Dirckx N, Devriese J, Nefyodova E, Cardoen R, St-Arnaud R, Tournoy J, Luyten FP, Maes C, Integrin-Linked Kinase Regulates Bone Formation by Controlling Cytoskeletal Organization and Modulating BMP and Wnt Signaling in Osteoprogenitors. J Bone Miner Res. 2017 Oct;32(10):2087-2102
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
5	J:320188 Gutierrez H, Kisiswa L, O'Keeffe GW, Smithen MJ, Wyatt S, Davies AM, Regulation of neurite growth by tumour necrosis superfamily member RANKL. Open Biol. 2013 Jan 8;3(1):120150
1	J:357895 Houchen CJ, Ghanem S, Kaartinen V, Bumann EE, TGF-beta signaling in the cranial neural crest affects late-stage mandibular bone resorption and length. Front Physiol. 2024;15:1435594
2	J:54076 Hsu H, Lacey DL, Dunstan CR, Solovyev I, Colombero A, Timms E, Tan HL, Elliott G, Kelley MJ, Sarosi I, Wang L, Xia XZ, Elliott R, Chiu L, Black T, Scully S, Capparelli C, Morony S, Shimamoto G, Bass MB, Boyle WJ, Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3540-5
1	J:277787 Ikuta K, Fukuda A, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Tsuda M, Kimura Y, Matsumoto Y, Kimura Y, Maruno T, Kanda K, Nishi K, Takaori K, Uemoto S, Takaishi S, Chiba T, Nishi E, Seno H, Nardilysin inhibits pancreatitis and suppresses pancreatic ductal adenocarcinoma initiation in mice. Gut. 2019 May;68(5):882-892
3	J:340406 Lai Y, Guo Y, Liao C, Mao C, Liu J, Ren C, Yang W, Luo L, Chen W, Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development. Sci Rep. 2023 Sep 13;13(1):15170
10	J:109487 Lange AW, Yutzey KE, NFATc1 expression in the developing heart valves is responsive to the RANKL pathway and is required for endocardial expression of cathepsin K. Dev Biol. 2006 Apr 15;292(2):407-17
1	J:293206 Munoz JJ, Tobajas E, Juara S, Montero S, Zapata AG, FoxN1 mediates thymic cortex-medulla differentiation through modifying a developmental pattern based on epithelial tubulogenesis. Histochem Cell Biol. 2019 Dec;152(6):397-413
1*	J:274110 Nakayama Y, Masuda Y, Ohta H, Tanaka T, Washida M, Nabeshima YI, Miyake A, Itoh N, Konishi M, Fgf21 regulates T-cell development in the neonatal and juvenile thymus. Sci Rep. 2017 Mar 23;7(1):330
5	J:88395 Ohazama A, Courtney JM, Sharpe PT, Opg, Rank, and Rankl in Tooth Development: Co-ordination of Odontogenesis and Osteogenesis. J Dent Res. 2004 Mar;83(3):241-4
2*	J:184087 Sugiyama M, Nakato G, Jinnohara T, Akiba H, Okumura K, Ohno H, Yoshida H, Expression pattern changes and function of RANKL during mouse lymph node microarchitecture development. Int Immunol. 2012 Jun;24(6):369-78
2*	J:320741 Vesela B, Svandova E, Hovorakova M, Peterkova R, Kratochvilova A, Pasovska M, Ramesova A, Lesot H, Matalova E, Specification of Sprouty2 functions in osteogenesis in in vivo context. Organogenesis. 2019;15(4):111-119