Gene Expression Literature Summary

• Symbol: Sphk1
• Name: sphingosine kinase 1
• ID: MGI:1316649

14 matching records from 14 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E7.5	E8.5	E9.5	E10.5	E11	E11.5	E12.5	E14	E14.5	E15	E15.5	E16.5	E17	E17.5	E18.5	P
Immunohistochemistry (section)								1		1			1
In situ RNA (section)					1		1										1
In situ RNA (whole mount)					1
Northern blot	1					1					1			1			1
RT-PCR		1	1	1	4	1	3	2	1	1		1	1	1	2	3	3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Sphk1  sphingosine kinase 1   (Synonyms: 1110006G24Rik, SK1)
Results	Reference
5	J:145748 Kirby RJ, Jin Y, Fu J, Cubillos J, Swertfeger D, Arend LJ, Dynamic regulation of sphingosine-1-phosphate homeostasis during development of mouse metanephric kidney. Am J Physiol Renal Physiol. 2009 Mar;296(3):F634-41
2	J:294595 Koppes E, Shaffer B, Sadovsky E, Himes K, Barak Y, Sadovsky Y, Chaillet JR, Klf14 is an imprinted transcription factor that regulates placental growth. Placenta. 2019 Dec;88:61-67
1*	J:255485 Li S, Teegarden A, Bauer EM, Choi J, Messaddeq N, Hendrix DA, Ganguli-Indra G, Leid M, Indra AK, Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development. Sci Rep. 2017 Oct 18;7(1):13427
5*	J:62994 Liu H, Sugiura M, Nava VE, Edsall LC, Kono K, Poulton S, Milstien S, Kohama T, Spiegel S, Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform. J Biol Chem. 2000 Jun 30;275(26):19513-20
1	J:169062 Lopez-Juarez A, Morales-Lazaro S, Sanchez-Sanchez R, Sunkara M, Lomeli H, Velasco I, Morris AJ, Escalante-Alcalde D, Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development. Glia. 2011 Apr;59(4):577-89
2	J:258670 Mahany EB, Han X, Borges BC, da Silveira Cruz-Machado S, Allen SJ, Garcia-Galiano D, Hoenerhoff MJ, Bellefontaine NH, Elias CF, Obesity and High-Fat Diet Induce Distinct Changes in Placental Gene Expression and Pregnancy Outcome. Endocrinology. 2018 Apr 1;159(4):1718-1733
2	J:180974 Meng H, Yuan Y, Lee VM, Loss of Sphingosine kinase 1/S1P signaling impairs cell growth and survival of neurons and progenitor cells in the developing sensory ganglia. PLoS One. 2011;6(11):e27150
1	J:103755 Mizugishi K, Yamashita T, Olivera A, Miller GF, Spiegel S, Proia RL, Essential role for sphingosine kinases in neural and vascular development. Mol Cell Biol. 2005 Dec;25(24):11113-21
1	J:154029 Munger SC, Aylor DL, Syed HA, Magwene PM, Threadgill DW, Capel B, Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal. Genes Dev. 2009 Nov 1;23(21):2521-36
1	J:161950 O'Brien KB, Alberich-Jorda M, Yadav N, Kocher O, Diruscio A, Ebralidze A, Levantini E, Sng NJ, Bhasin M, Caron T, Kim D, Steidl U, Huang G, Halmos B, Rodig SJ, Bedford MT, Tenen DG, Kobayashi S, CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells. Development. 2010 Jul;137(13):2147-56
7	J:243381 Serafimidis I, Rodriguez-Aznar E, Lesche M, Yoshioka K, Takuwa Y, Dahl A, Pan D, Gavalas A, Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. PLoS Biol. 2017 Mar;15(3):e2000949
1	J:310313 Vinjamur DS, Wade KJ, Mohamad SF, Haar JL, Sawyer ST, Lloyd JA, Kruppel-like transcription factors KLF1 and KLF2 have unique and coordinate roles in regulating embryonic erythroid precursor maturation. Haematologica. 2014 Oct;99(10):1565-73
3*	J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76
6*	J:107068 Wendler CC, Rivkees SA, Sphingosine-1-phosphate inhibits cell migration and endothelial to mesenchymal cell transformation during cardiac development. Dev Biol. 2006 Mar 15;291(2):264-77