Gene Expression Literature Summary

• Symbol: Matn4
• Name: matrilin 4
• ID: MGI:1328314

15 matching records from 15 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E10.5	E11.5	E12.5	E13.5	E14	E14.5	E15.5	E16.5	E18.5	E19	E19.5	E	P
Immunohistochemistry (section)	1	1		1		1	1	1	1	1				5
In situ RNA (section)								1					1	1
In situ RNA (whole mount)			1	1
Northern blot														3
Western blot														3
RT-PCR			1	2	3		1			2		1		3
cDNA clones											1		1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Matn4  matrilin 4   (Synonyms: matrilin-4)
Results	Reference
3	J:217339 Beiser KU, Glaser A, Kleinschmidt K, Scholl I, Roth R, Li L, Gretz N, Mechtersheimer G, Karperien M, Marchini A, Richter W, Rappold GA, Identification of novel SHOX target genes in the developing limb using a transgenic mouse model. PLoS One. 2014;9(6):e98543
2	J:336100 Brutsch SM, Madzharova E, Pantasis S, Wustemann T, Gurri S, Steenbock H, Gazdhar A, Kuhn G, Angel P, Bellusci S, Brinckmann J, Auf dem Keller U, Werner S, Bordoli MR, Mesenchyme-derived vertebrate lonesome kinase controls lung organogenesis by altering the matrisome. Cell Mol Life Sci. 2023 Mar 15;80(4):89
1	J:308983 Farmer DT, Mlcochova H, Zhou Y, Koelling N, Wang G, Ashley N, Bugacov H, Chen HJ, Parvez R, Tseng KC, Merrill AE, Maxson RE Jr, Wilkie AOM, Crump JG, Twigg SRF, The developing mouse coronal suture at single-cell resolution. Nat Commun. 2021 Aug 10;12(1):4797
4	J:204883 Feenstra JM, Kanaya K, Pira CU, Hoffman SE, Eppey RJ, Oberg KC, Detection of genes regulated by Lmx1b during limb dorsalization. Dev Growth Differ. 2012 May;54(4):451-62
1	J:241397 Kamper M, Paulsson M, Zaucke F, Absence of collagen IX accelerates hypertrophic differentiation in the embryonic mouse spine through a disturbance of the Ihh-PTHrP feedback loop. Cell Tissue Res. 2017 Feb;367(2):359-367
8*	J:69493 Klatt AR, Nitsche DP, Kobbe B, Macht M, Paulsson M, Wagener R, Molecular structure, processing, and tissue distribution of matrilin-4. J Biol Chem. 2001 May 18;276(20):17267-75
2	J:80149 Klatt AR, Paulsson M, Wagener R, Expression of matrilins during maturation of mouse skeletal tissues. Matrix Biol. 2002 Apr;21(3):289-96
3	J:87676 Ko Y, Kobbe B, Nicolae C, Miosge N, Paulsson M, Wagener R, Aszodi A, Matrilin-3 is dispensable for mouse skeletal growth and development. Mol Cell Biol. 2004 Feb;24(4):1691-9
1	J:314899 Lee WJ, Chatterjee S, Yap SP, Lim SL, Xing X, Kraus P, Sun W, Hu X, Sivakamasundari V, Chan HY, Kolatkar PR, Prabhakar S, Lufkin T, An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos. Biomed Res Int. 2017;2017:8932583
2	J:150519 Malin D, Sonnenberg-Riethmacher E, Guseva D, Wagener R, Aszodi A, Irintchev A, Riethmacher D, The extracellular-matrix protein matrilin 2 participates in peripheral nerve regeneration. J Cell Sci. 2009 Apr 1;122(Pt 7):995-1004
1*	J:308708 Martinez ME, Hernandez A, The Type 3 Deiodinase Is a Critical Modulator of Thyroid Hormone Sensitivity in the Fetal Brain. Front Neurosci. 2021;15:703730
5	J:91587 Mates L, Nicolae C, Morgelin M, Deak F, Kiss I, Aszodi A, Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities. Matrix Biol. 2004 Jun;23(3):195-204
1	J:112002 van der Weyden L, Wei L, Luo J, Yang X, Birk DE, Adams DJ, Bradley A, Chen Q, Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis. Am J Pathol. 2006 Aug;169(2):515-27
2	J:170400 Vickerman L, Neufeld S, Cobb J, Shox2 function couples neural, muscular and skeletal development in the proximal forelimb. Dev Biol. 2011 Feb 15;350(2):323-36
4*	J:50116 Wagener R, Kobbe B, Paulsson M, Matrilin-4, a new member of the matrilin family of extracellular matrix proteins. FEBS Lett. 1998 Sep 25;436(1):123-7