Symbol Name ID |
Blm
Bloom syndrome, RecQ like helicase MGI:1328362 |
Age | E0.5 | E9.5 | E10.5 | E11.5 | E12.5 | E13.5 | E16.5 | P |
Immunohistochemistry (section) | 1 | 1 | 1 | |||||
Immunohistochemistry (whole mount) | 1 | |||||||
Northern blot | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |
Western blot | 1 | 1 | 1 | |||||
RT-PCR | 2 | 1 |
Blm Bloom syndrome, RecQ like helicase | |
Results | Reference |
7* | J:50843 Chester N, Kuo F, Kozak C, O'Hara CD, Leder P, Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene. Genes Dev. 1998 Nov 1;12(21):3382-93 |
1 | J:273415 Dupays L, Towers N, Wood S, David A, Stuckey DJ, Mohun T, Furin, a transcriptional target of NKX2-5, has an essential role in heart development and function. PLoS One. 2019;14(3):e0212992 |
1* | J:316646 Guiraldelli MF, Eyster C, Pezza RJ, Genome instability and embryonic developmental defects in RMI1 deficient mice. DNA Repair (Amst). 2013 Oct;12(10):835-43 |
1 | J:335565 Huang T, Wu X, Wang S, Bao Z, Wan Y, Wang Z, Li M, Yu X, Lv Y, Liu Z, Chen X, Chan WY, Gao F, Lu G, Chen ZJ, Liu H, SPIDR is required for homologous recombination during mammalian meiosis. Nucleic Acids Res. 2023 May 8;51(8):3855-3868 |
3 | J:131948 Liu L, Bailey SM, Okuka M, Munoz P, Li C, Zhou L, Wu C, Czerwiec E, Sandler L, Seyfang A, Blasco MA, Keefe DL, Telomere lengthening early in development. Nat Cell Biol. 2007 Dec;9(12):1436-41 |
2* | J:86827 McDaniel LD, Chester N, Watson M, Borowsky AD, Leder P, Schultz RA, Chromosome instability and tumor predisposition inversely correlate with BLM protein levels. DNA Repair (Amst). 2003 Dec 9;2(12):1387-404 |
2* | J:340875 Zhou Z, Yin H, Suye S, Ren Z, Yan L, Shi L, Fu C, Fance deficiency inhibits primordial germ cell proliferation associated with transcription-replication conflicts accumulate and DNA repair defects. J Ovarian Res. 2023 Aug 10;16(1):160 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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