Symbol Name ID |
Cdk5r2
cyclin dependent kinase 5, regulatory subunit 2 MGI:1330828 |
Age | E13.5 | E14 | E14.5 | E16 | E16.5 | E17 | E18 | E18.5 | P |
Immunohistochemistry (section) | 1 | ||||||||
In situ RNA (section) | 1 | 1 | 2 | 1 | 2 | 2 | 2 | 3 | |
Northern blot | 1 | ||||||||
Western blot | 1 | 2 | 4 | ||||||
RT-PCR | 1 | 1 | |||||||
cDNA clones | 1 |
Cdk5r2 cyclin dependent kinase 5, regulatory subunit 2 (Synonyms: B230310J22Rik, p39) | |
Results | Reference |
4* | J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247 |
3 | J:107294 Chang Y, Ostling P, Akerfelt M, Trouillet D, Rallu M, Gitton Y, El Fatimy R, Fardeau V, Le Crom S, Morange M, Sistonen L, Mezger V, Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expression. Genes Dev. 2006 Apr 1;20(7):836-47 |
1* | J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582 |
2 | J:316721 Fu AK, Hung KW, Wong HH, Fu WY, Ip NY, Cdk5 phosphorylates a component of the HDAC complex and regulates histone acetylation during neuronal cell death. Neurosignals. 2013;21(1-2):55-60 |
1 | J:70189 Hevner RF, Shi L, Justice N, Hsueh Y, Sheng M, Smiga S, Bulfone A, Goffinet AM, Campagnoni AT, Rubenstein JL, Tbr1 regulates differentiation of the preplate and layer 6. Neuron. 2001 Feb;29(2):353-66 |
4* | J:354376 Humbert S, Lanier LM, Tsai LH, Synaptic localization of p39, a neuronal activator of cdk5. Neuroreport. 2000 Jul 14;11(10):2213-6 |
1 | J:338083 Hwang I, Kim BS, Ko HR, Cho S, Lee HY, Cho SW, Ryu D, Shim S, Ahn JY, Cerebellar dysfunction and schizophrenia-like behavior in Ebp1-deficient mice. Mol Psychiatry. 2022 Apr;27(4):2030-2041 |
1* | J:71181 Ko J, Humbert S, Bronson RT, Takahashi S, Kulkarni AB, Li E, Tsai LH, p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment. J Neurosci. 2001 Sep 1;21(17):6758-71 |
1* | J:74989 McEvilly RJ, de Diaz MO, Schonemann MD, Hooshmand F, Rosenfeld MG, Transcriptional regulation of cortical neuron migration by POU domain factors. Science. 2002 Feb 22;295(5559):1528-32 |
6* | J:67864 Ohshima T, Ogawa M, Veeranna, Hirasawa M, Longenecker G, Ishiguro K, Pant HC, Brady RO, Kulkarni AB, Mikoshiba K, Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain. Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2764-9 |
2 | J:305001 Ouyang L, Chen Y, Wang Y, Chen Y, Fu AKY, Fu WY, Ip NY, p39-associated Cdk5 activity regulates dendritic morphogenesis. Sci Rep. 2020 Oct 30;10(1):18746 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/05/2024 MGI 6.24 |
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