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Gene Expression Literature Summary
Symbol
Name
ID
Enam
enamelin
MGI:1333772

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E11.5 E12.5 E13.5 E14.5 E15.5 E16.5 E17.5 E18.5 P
Immunohistochemistry (section) 1 7
In situ RNA (section) 1 1 1 1 1 1 1 1
Western blot 1 1 1 1 1 1 1 3
RT-PCR 1 1 1 1 1 2 3 3 9

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Enam  enamelin   (Synonyms: abte)
Results  Reference
1J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365
1J:140568 Barron MJ, Brookes SJ, Draper CE, Garrod D, Kirkham J, Shore RC, Dixon MJ, The cell adhesion molecule nectin-1 is critical for normal enamel formation in mice. Hum Mol Genet. 2008 Nov 15;17(22):3509-20
1J:245023 Cantu C, Pagella P, Shajiei TD, Zimmerli D, Valenta T, Hausmann G, Basler K, Mitsiadis TA, A cytoplasmic role of Wnt/beta-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation. Sci Signal. 2017 Feb 07;10(465)
1J:184287 Duverger O, Zah A, Isaac J, Sun HW, Bartels AK, Lian JB, Berdal A, Hwang J, Morasso MI, Neural crest deletion of Dlx3 leads to major dentin defects through down-regulation of Dspp. J Biol Chem. 2012 Apr 6;287(15):12230-40
1J:317814 Fan L, Ou YJ, Zhu YX, Liang YD, Zhou Y, Wang YN, Lif Deficiency Leads to Iron Transportation Dysfunction in Ameloblasts. J Dent Res. 2022 Jan;101(1):63-72
2*J:146765 Golonzhka O, Metzger D, Bornert JM, Bay BK, Gross MK, Kioussi C, Leid M, Ctip2/Bcl11b controls ameloblast formation during mammalian odontogenesis. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4278-83
1J:233764 Gullard A, Gluhak-Heinrich J, Papagerakis S, Sohn P, Unterbrink A, Chen S, MacDougall M, MEPE Localization in the Craniofacial Complex and Function in Tooth Dentin Formation. J Histochem Cytochem. 2016 Apr;64(4):224-36
1J:182873 Jheon AH, Mostowfi P, Snead ML, Ihrie RA, Sone E, Pramparo T, Attardi LD, Klein OD, PERP regulates enamel formation via effects on cell-cell adhesion and gene expression. J Cell Sci. 2011 Mar 1;124(Pt 5):745-54
24J:188148 Landin MA, Shabestari M, Babaie E, Reseland JE, Osmundsen H, Gene Expression Profiling during Murine Tooth Development. Front Genet. 2012;3:139
1J:203117 Li X, Venugopalan SR, Cao H, Pinho FO, Paine ML, Snead ML, Semina EV, Amendt BA, A model for the molecular underpinnings of tooth defects in Axenfeld-Rieger syndrome. Hum Mol Genet. 2014 Jan 1;23(1):194-208
1*J:132157 Nakamura T, de Vega S, Fukumoto S, Jimenez L, Unda F, Yamada Y, Transcription factor epiprofin is essential for tooth morphogenesis by regulating epithelial cell fate and tooth number. J Biol Chem. 2008 Feb 22;283(8):4825-33
1J:309378 Naveau A, Zhang B, Meng B, Sutherland MT, Prochazkova M, Wen T, Marangoni P, Jones KB, Cox TC, Ganss B, Jheon AH, Klein OD, Isl1 Controls Patterning and Mineralization of Enamel in the Continuously Renewing Mouse Incisor. J Bone Miner Res. 2017 Nov;32(11):2219-2231
1J:103753 Rios H, Koushik SV, Wang H, Wang J, Zhou HM, Lindsley A, Rogers R, Chen Z, Maeda M, Kruzynska-Frejtag A, Feng JQ, Conway SJ, periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype. Mol Cell Biol. 2005 Dec;25(24):11131-44
3*J:147982 Sehic A, Khuu C, Risnes S, Osmundsen H, Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse. Eur J Oral Sci. 2009 Apr;117(2):93-104
3*J:165465 Sehic A, Risnes S, Khan QE, Khuu C, Osmundsen H, Gene expression and dental enamel structure in developing mouse incisor. Eur J Oral Sci. 2010 Apr;118(2):118-30
1*J:270176 Tian Z, Lv X, Zhang M, Wang X, Chen Y, Tang P, Xu P, Zhang L, Wu B, Zhang L, Deletion of epithelial cell-specific Cdc42 leads to enamel hypermaturation in a conditional knockout mouse model. Biochim Biophys Acta Mol Basis Dis. 2018 Aug;1864(8):2623-2632
1J:312375 Yamada A, Yoshizaki K, Ishikawa M, Saito K, Chiba Y, Fukumoto E, Hino R, Hoshikawa S, Chiba M, Nakamura T, Iwamoto T, Fukumoto S, Connexin 43-Mediated Gap Junction Communication Regulates Ameloblast Differentiation via ERK1/2 Phosphorylation. Front Physiol. 2021;12:748574
1*J:288330 Yasukawa M, Ishida K, Yuge Y, Hanaoka M, Minami Y, Ogawa M, Sasaki T, Saito M, Tsuji T, Dpysl4 is involved in tooth germ morphogenesis through growth regulation, polarization and differentiation of dental epithelial cells. Int J Biol Sci. 2013;9(4):382-90
1*J:165548 Yoshida T, Miyoshi J, Takai Y, Thesleff I, Cooperation of nectin-1 and nectin-3 is required for normal ameloblast function and crown shape development in mouse teeth. Dev Dyn. 2010 Oct;239(10):2558-69
1J:319643 Zhang B, Meng B, Viloria E, Naveau A, Ganss B, Jheon AH, The Role of Epithelial Stat3 in Amelogenesis during Mouse Incisor Renewal. Cells Tissues Organs. 2018;205(2):63-71

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory