Symbol Name ID |
Casp14
caspase 14 MGI:1335092 |
Age | E7 | E11 | E12 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E17.5 | E18 | E18.5 | P |
Immunohistochemistry (section) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | 2 | ||||
Northern blot | 1 | 1 | 1 | 1 | 1 | |||||||||
Western blot | 1 | 2 | 3 | 2 | 3 | 2 | ||||||||
RT-PCR | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 2 | ||||||
cDNA clones | 1 | |||||||||||||
RNase protection | 1 |
Casp14 caspase 14 (Synonyms: MICE, mini-ICE) | |
Results | Reference |
4 | J:141601 Bayo P, Sanchis A, Bravo A, Cascallana JL, Buder K, Tuckermann J, Schutz G, Perez P, Glucocorticoid receptor is required for skin barrier competence. Endocrinology. 2008 Mar;149(3):1377-88 |
12* | J:103134 Fischer H, Rossiter H, Ghannadan M, Jaeger K, Barresi C, Declercq W, Tschachler E, Eckhart L, Caspase-14 but not caspase-3 is processed during the development of fetal mouse epidermis. Differentiation. 2005 Oct;73(8):406-13 |
2 | J:147182 Golonzhka O, Liang X, Messaddeq N, Bornert JM, Campbell AL, Metzger D, Chambon P, Ganguli-Indra G, Leid M, Indra AK, Dual role of COUP-TF-interacting protein 2 in epidermal homeostasis and permeability barrier formation. J Invest Dermatol. 2009 Jun;129(6):1459-70 |
5* | J:180909 Hoste E, Kemperman P, Devos M, Denecker G, Kezic S, Yau N, Gilbert B, Lippens S, De Groote P, Roelandt R, Van Damme P, Gevaert K, Presland RB, Takahara H, Puppels G, Caspers P, Vandenabeele P, Declercq W, Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin. J Invest Dermatol. 2011 Nov;131(11):2233-41 |
5* | J:50861 Hu S, Snipas SJ, Vincenz C, Salvesen G, Dixit VM, Caspase-14 is a novel developmentally regulated protease. J Biol Chem. 1998 Nov 6;273(45):29648-53 |
6* | J:74158 Kuechle MK, Predd HM, Fleckman P, Dale BA, Presland RB, Caspase-14, a keratinocyte specific caspase: mRNA splice variants and expression pattern in embryonic and adult mouse. Cell Death Differ. 2001 Aug;8(8):868-70 |
1* | J:255485 Li S, Teegarden A, Bauer EM, Choi J, Messaddeq N, Hendrix DA, Ganguli-Indra G, Leid M, Indra AK, Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development. Sci Rep. 2017 Oct 18;7(1):13427 |
1 | J:352165 Lin Y, Tang W, Huang P, Wang Z, Duan L, Jia C, Sun R, Liu L, Shen J, Denticleless E3 ubiquitin protein ligase (DTL) maintains the proliferation and differentiation of epidermis and hair follicles during skin development. Dev Dyn. 2024 Jul;253(7):635-647 |
1 | J:154022 Lopez RG, Garcia-Silva S, Moore SJ, Bereshchenko O, Martinez-Cruz AB, Ermakova O, Kurz E, Paramio JM, Nerlov C, C/EBPalpha and beta couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation. Nat Cell Biol. 2009 Oct;11(10):1181-90 |
1 | J:341642 Schwartz B, Levi H, Menon G, Maria R, Upcher A, Kotlovski Y, Oss-Ronen L, Cohen I, ZNF750 Regulates Skin Barrier Function by Driving Cornified Envelope and Lipid Processing Pathways. J Invest Dermatol. 2023 Sep 3; |
1 | J:358134 Soma S, Murakami K, Fukuchi Y, Kunimoto H, Nakajima H, O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation. Stem Cells. 2024 Jan 13;42(1):55-63 |
2* | J:261957 Svandova EB, Vesela B, Lesot H, Poliard A, Matalova E, Expression of Fas, FasL, caspase-8 and other factors of the extrinsic apoptotic pathway during the onset of interdigital tissue elimination. Histochem Cell Biol. 2017 Apr;147(4):497-510 |
1 | J:260842 Urwyler-Rosselet C, Tanghe G, Leurs K, Gilbert B, De Rycke R, De Bruyne M, Lippens S, Bartunkova S, De Groote P, Niessen C, Haftek M, Vandenabeele P, Declercq W, Keratinocyte-Specific Ablation of RIPK4 Allows Epidermal Cornification but Impairs Skin Barrier Formation. J Invest Dermatol. 2018 Jun;138(6):1268-1278 |
2 | J:316173 Vesela B, Svandova E, Vanden Berghe T, Tucker AS, Vandenabeele P, Matalova E, Non-apoptotic role for caspase-7 in hair follicles and the surrounding tissue. J Mol Histol. 2015 Oct;46(4-5):443-55 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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