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Gene Expression Literature Summary
Symbol
Name
ID
Sema6c
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
MGI:1338032

15 matching records from 15 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E9 E9.5 E10.5 E11.5 E12.5 E13 E13.5 E14 E14.5 E15.5 E16 E16.5 E17.5 E18 E18.5 P
Immunohistochemistry (section) 1 1 1 1 1 1 1
In situ RNA (section) 1 3 1 2 2 1 1 1 1 2
In situ RNA (whole mount) 1 1 1
In situ reporter (knock in) 1
Western blot 1
RT-PCR 1 1 2 2 1 2 1 1 1 1 4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Sema6c  sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C   (Synonyms: mKIAA1869, Semay, Sema Y)
Results  Reference
9J:116537 Burgaya F, Fontana X, Martinez A, Montolio M, Mingorance A, Simo S, del Rio JA, Soriano E, Semaphorin 6C leads to GSK-3-dependent growth cone collapse and redistributes after entorhino-hippocampal axotomy. Mol Cell Neurosci. 2006 Nov;33(3):321-34
2J:143477 Chotalia M, Smallwood SA, Ruf N, Dawson C, Lucifero D, Frontera M, James K, Dean W, Kelsey G, Transcription is required for establishment of germline methylation marks at imprinted genes. Genes Dev. 2009 Jan 1;23(1):105-17
1*J:100439 Cohen S, Funkelstein L, Livet J, Rougon G, Henderson CE, Castellani V, Mann F, A semaphorin code defines subpopulations of spinal motor neurons during mouse development. Eur J Neurosci. 2005 Apr;21(7):1767-76
2*J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
2J:111207 Dionne MS, Brunet LJ, Eimon PM, Harland RM, Noggin is required for correct guidance of dorsal root ganglion axons. Dev Biol. 2002 Nov 15;251(2):283-93
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1J:188362 Kuwajima T, Yoshida Y, Takegahara N, Petros TJ, Kumanogoh A, Jessell TM, Sakurai T, Mason C, Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing. Neuron. 2012 May 24;74(4):676-90
5J:91290 Lillesaar C, Fried K, Neurites from trigeminal ganglion explants grown in vitro are repelled or attracted by tooth-related tissues depending on developmental stage. Neuroscience. 2004;125(1):149-61
1J:330969 Martins LF, Brambilla I, Motta A, de Pretis S, Bhat GP, Badaloni A, Malpighi C, Amin ND, Imai F, Almeida RD, Yoshida Y, Pfaff SL, Bonanomi D, Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity. Neuron. 2022 Oct 7;
2J:273473 McKey J, Bunce C, Batchvarov IS, Ornitz DM, Capel B, Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5570-5575
6J:254695 Peng Y, Song L, Li D, Kesterson R, Wang J, Wang L, Rokosh G, Wu B, Wang Q, Jiao K, Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in mice. Cardiovasc Res. 2016 Nov 1;112(2):532-542
3*J:79112 Qu X, Wei H, Zhai Y, Que H, Chen Q, Tang F, Wu Y, Xing G, Zhu Y, Liu S, Fan M, He F, Identification, characterization, and functional study of the two novel human members of the semaphorin gene family. J Biol Chem. 2002 Sep 20;277(38):35574-85
5*J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767
3J:144660 Yoshida Y, Han B, Mendelsohn M, Jessell TM, PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord. Neuron. 2006 Dec 7;52(5):775-88

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/09/2024
MGI 6.24
The Jackson Laboratory