Symbol Name ID |
Fhl2
four and a half LIM domains 2 MGI:1338762 |
Age | E7.5 | E8 | E8.5 | E9.5 | E10 | E10.5 | E11.5 | E12.5 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16.5 | E17 | E17.5 | E18 | E18.5 | E | P |
Immunohistochemistry (section) | 2 | 2 | 2 | 1 | 1 | |||||||||||||||
In situ RNA (section) | 1 | 1 | 1 | 2 | 1 | 4 | 1 | 1 | 1 | 2 | ||||||||||
In situ RNA (whole mount) | 1 | 3 | 4 | 2 | 1 | 3 | 1 | |||||||||||||
In situ reporter (knock in) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |||||||||||||
Northern blot | 1 | |||||||||||||||||||
Western blot | 1 | 1 | 1 | 1 | 1 | |||||||||||||||
RT-PCR | 1 | 3 | 2 | 1 | 1 | 3 | 3 | 1 | 1 | 2 | ||||||||||
cDNA clones | 1 |
Fhl2 four and a half LIM domains 2 (Synonyms: SLIM3) | |
Results | Reference |
1 | J:334092 Broadway-Stringer S, Jiang H, Wadmore K, Hooper C, Douglas G, Steeples V, Azad AJ, Singer E, Reyat JS, Galatik F, Ehler E, Bennett P, Kalisch-Smith JI, Sparrow DB, Davies B, Djinovic-Carugo K, Gautel M, Watkins H, Gehmlich K, Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2. Cells. 2023 Feb 24;12(5) |
2* | J:171293 Campbell GR, Baudhuin A, Vranizan K, Ngai J, Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling. Mol Cell Neurosci. 2011 Feb;46(2):548-61 |
6* | J:63769 Chu P, Ruiz-Lozano P, Zhou Q, Cai C, Chen J, Expression patterns of FHL/SLIM family members suggest important functional roles in skeletal muscle and cardiovascular system. Mech Dev. 2000 Jul;95(1-2):259-65 |
2* | J:168654 Chung YC, Tsai YJ, Shiu TY, Sun YY, Wang PF, Chen CL, Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):84-92 |
1 | J:319391 Decourtye L, McCallum-Loudeac JA, Zellhuber-McMillan S, Young E, Sircombe KJ, Wilson MJ, Characterization of a novel Lbx1 mouse loss of function strain. Differentiation. 2021 Dec 9;123:30-41 |
5* | J:313274 Du J, Wang Q, Wang L, Wang X, Yang P, The expression pattern of FHL2 during mouse molar development. J Mol Histol. 2012 Jun;43(3):289-95 |
3* | J:317089 Du J, Wang Q, Yang P, Wang X, FHL2 mediates tooth development and human dental pulp cell differentiation into odontoblasts, partially by interacting with Runx2. J Mol Histol. 2016 Apr;47(2):195-202 |
3 | J:78371 Du X, Hublitz P, Gunther T, Wilhelm D, Englert C, Schule R, The LIM-only coactivator FHL2 modulates WT1 transcriptional activity during gonadal differentiation. Biochim Biophys Acta. 2002 Aug 19;1577(1):93-101 |
3* | J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257 |
3* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
2 | J:94194 Hill AA, Riley PR, Differential regulation of Hand1 homodimer and Hand1-E12 heterodimer activity by the cofactor FHL2. Mol Cell Biol. 2004 Nov;24(22):9835-47 |
1 | J:101263 Ivins S, Lammerts van Beuren K, Roberts C, James C, Lindsay E, Baldini A, Ataliotis P, Scambler PJ, Microarray analysis detects differentially expressed genes in the pharyngeal region of mice lacking Tbx1. Dev Biol. 2005 Sep 15;285(2):554-69 |
2 | J:117793 Kudo LC, Karsten SL, Chen J, Levitt P, Geschwind DH, Genetic analysis of anterior-posterior expression gradients in the developing mammalian forebrain. Cereb Cortex. 2007 Sep;17(9):2108-22 |
1* | J:241850 Naiman N, Fujioka K, Fujino M, Valerius MT, Potter SS, McMahon AP, Kobayashi A, Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 May 22;41(4):349-365.e3 |
1* | J:171730 Ogaki S, Harada S, Shiraki N, Kume K, Kume S, An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells. BMC Dev Biol. 2011;11:13 |
8* | J:319571 Renger A, Zafiriou MP, Noack C, Pavlova E, Becker A, Sharkova K, Bergmann MW, El-Armouche A, Zimmermann WH, Zelarayan LC, The four and a half LIM-domain 2 controls early cardiac cell commitment and expansion via regulating beta-catenin-dependent transcription. Stem Cells. 2013 May;31(5):928-40 |
3* | J:109334 Schafer K, Neuhaus P, Kruse J, Braun T, The homeobox gene Lbx1 specifies a subpopulation of cardiac neural crest necessary for normal heart development. Circ Res. 2003 Jan 10;92(1):73-80 |
3* | J:168863 Shi X, Bowlin KM, Garry DJ, Fhl2 interacts with Foxk1 and corepresses Foxo4 activity in myogenic progenitors. Stem Cells. 2010 Mar 31;28(3):462-9 |
4* | J:209112 Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H, The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754 |
8 | J:111284 Weinert S, Bergmann N, Luo X, Erdmann B, Gotthardt M, M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere. J Cell Biol. 2006 May 22;173(4):559-70 |
1* | J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130 |
2* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
3* | J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48 |
2 | J:184004 Yu J, Valerius MT, Duah M, Staser K, Hansard JK, Guo JJ, McMahon J, Vaughan J, Faria D, Georgas K, Rumballe B, Ren Q, Krautzberger AM, Junker JP, Thiagarajan RD, Machanick P, Gray PA, van Oudenaarden A, Rowitch DH, Stiles CD, Ma Q, Grimmond SM, Bailey TL, Little MH, McMahon AP, Identification of molecular compartments and genetic circuitry in the developing mammalian kidney. Development. 2012 May;139(10):1863-73 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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