Gene Expression Literature Summary

• Symbol: Parp1
• Name: poly (ADP-ribose) polymerase family, member 1
• ID: MGI:1340806

80 matching records from 80 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E5.5	E7.5	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16.5	E17	E17.5	E18	E18.5	E19.5	E20	E	P
Immunohistochemistry (section)					2	1	3	2	5	1	1	1	3		9		3	6		2		4	2	1	1	12
In situ RNA (section)							1				2				2					1		2			1	2
Immunohistochemistry (whole mount)	1		1								1		2		2		1					1
Western blot					1		1		1	1	3		5		4	1	3	2			1	3				11
RT-PCR		1									2			1			1		1	1	2					3
cDNA clones				1																						1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Parp1  poly (ADP-ribose) polymerase family, member 1   (Synonyms: 5830444G22Rik, Adprp, Adprt1, PARP, parp-1, sPARP-1)
Results	Reference
1	J:264269 Azimi M, Le TT, Brown NL, Presenilin gene function and Notch signaling feedback regulation in the developing mouse lens. Differentiation. 2018 Jul - Aug;102:40-52
1	J:266583 Baumgartner M, Olthof AM, Aquino GS, Hyatt KC, Lemoine C, Drake K, Sturrock N, Nguyen N, Al Seesi S, Kanadia RN, Minor spliceosome inactivation causes microcephaly, owing to cell cycle defects and death of self-amplifying radial glial cells. Development. 2018 Aug 28;145(17):dev166322
1	J:287985 Bosze B, Moon MS, Kageyama R, Brown NL, Simultaneous Requirements for Hes1 in Retinal Neurogenesis and Optic Cup-Stalk Boundary Maintenance. J Neurosci. 2020 Feb 12;40(7):1501-1513
1	J:341148 Bosze B, Suarez-Navarro J, Cajias I, Brzezinski Iv JA, Brown NL, Notch pathway mutants do not equivalently perturb mouse embryonic retinal development. PLoS Genet. 2023 Sep;19(9):e1010928
1	J:303632 Bosze B, Suarez-Navarro J, Soofi A, Lauderdale JD, Dressler GR, Brown NL, Multiple roles for Pax2 in the embryonic mouse eye. Dev Biol. 2021 Apr;472:18-29
1	J:304329 Chen D, He F, Lu T, Huang J, Li M, Cai D, Huang C, Chen D, Xiong F, VPS4B deficiency causes early embryonic lethality and induces signal transduction disorders of cell endocytosis. Genesis. 2021 Mar 7;:e23415
1	J:191131 Chen L, Faire M, Kissner MD, Laird DJ, Primordial germ cells and gastrointestinal stromal tumors respond distinctly to a cKit overactivating allele. Hum Mol Genet. 2013 Jan 15;22(2):313-27
1	J:230030 Cheng IC, Chen BC, Shuai HH, Chien FC, Chen P, Hsieh TS, Wuho Is a New Member in Maintaining Genome Stability through its Interaction with Flap Endonuclease 1. PLoS Biol. 2016 Jan;14(1):e1002349
1	J:173089 Daniel K, Lange J, Hached K, Fu J, Anastassiadis K, Roig I, Cooke HJ, Stewart AF, Wassmann K, Jasin M, Keeney S, Toth A, Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1. Nat Cell Biol. 2011 May;13(5):599-610
1	J:119857 Desmots F, Russell HR, Lee Y, Boyd K, McKinnon PJ, The reaper-binding protein scythe modulates apoptosis and proliferation during mammalian development. Mol Cell Biol. 2005 Dec;25(23):10329-37
1	J:309376 Ding M, Jin L, Xie L, Park SH, Tong Y, Wu D, Chhabra AB, Fu Z, Li X, A Murine Model for Human ECO Syndrome Reveals a Critical Role of Intestinal Cell Kinase in Skeletal Development. Calcif Tissue Int. 2018 Mar;102(3):348-357
2	J:162165 Dudley B, Palumbo C, Nalepka J, Molyneaux K, BMP signaling controls formation of a primordial germ cell niche within the early genital ridges. Dev Biol. 2010 Jul 1;343(1-2):84-93
1*	J:265712 Dziedzic SA, Su Z, Jean Barrett V, Najafov A, Mookhtiar AK, Amin P, Pan H, Sun L, Zhu H, Ma A, Abbott DW, Yuan J, ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC. Nat Cell Biol. 2018 Jan;20(1):58-68
4	J:196310 Ene AC, Park S, Edelmann W, Taketo T, Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression. Dev Biol. 2013 May 1;377(1):213-23
2*	J:320745 Ferguson CJ, Urso O, Bodrug T, Gassaway BM, Watson ER, Prabu JR, Lara-Gonzalez P, Martinez-Chacin RC, Wu DY, Brigatti KW, Puffenberger EG, Taylor CM, Haas-Givler B, Jinks RN, Strauss KA, Desai A, Gabel HW, Gygi SP, Schulman BA, Brown NG, Bonni A, APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain. Mol Cell. 2022 Jan 6;82(1):90-105.e13
1	J:253771 Gaudreau MC, Grapton D, Helness A, Vadnais C, Fraszczak J, Shooshtarizadeh P, Wilhelm B, Robert F, Heyd F, Moroy T, Heterogeneous Nuclear Ribonucleoprotein L is required for the survival and functional integrity of murine hematopoietic stem cells. Sci Rep. 2016 Jun 7;6:27379
1*	J:217689 Guzman-Ayala M, Sachs M, Koh FM, Onodera C, Bulut-Karslioglu A, Lin CJ, Wong P, Nitta R, Song JS, Ramalho-Santos M, Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast. Development. 2015 Jan 1;142(1):118-27
1	J:161356 Hajkova P, Jeffries SJ, Lee C, Miller N, Jackson SP, Surani MA, Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway. Science. 2010 Jul 2;329(5987):78-82
6*	J:130337 Hakme A, Huber A, Dolle P, Schreiber V, The macroPARP genes Parp-9 and Parp-14 are developmentally and differentially regulated in mouse tissues. Dev Dyn. 2008 Jan;237(1):209-15
2	J:162637 Hang CT, Yang J, Han P, Cheng HL, Shang C, Ashley E, Zhou B, Chang CP, Chromatin regulation by Brg1 underlies heart muscle development and disease. Nature. 2010 Jul 1;466(7302):62-7
1*	J:207609 Hilliard SA, Yao X, El-Dahr SS, Mdm2 is required for maintenance of the nephrogenic niche. Dev Biol. 2014 Mar 1;387(1):1-14
1*	J:248708 Hoffmeister M, Krieg J, Ehrke A, Seigfried FA, Wischmann L, Dietmann P, Kuhl SJ, Oess S, Developmental neurogenesis in mouse and Xenopus is impaired in the absence of Nosip. Dev Biol. 2017 Sep 1;429(1):200-212
2	J:69602 Hohenstein P, Kielman MF, Breukel C, Bennett LM, Wiseman R, Krimpenfort P, Cornelisse C, van Ommen GJ, Devilee P, Fodde R, A targeted mouse Brca1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage. Oncogene. 2001 May 3;20(20):2544-50
1	J:333827 Huang C, Zhao S, Yang Y, Guo T, Ke H, Mi X, Qin Y, Chen ZJ, Zhao S, TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis. J Clin Invest. 2023 Mar 1;133(5)
2	J:326085 Huang TC, Wang YF, Vazquez-Ferrer E, Theofel I, Requena CE, Hanna CW, Kelsey G, Hajkova P, Sex-specific chromatin remodelling safeguards transcription in germ cells. Nature. 2021 Dec;600(7890):737-742
4	J:316683 Huh MS, Ivanochko D, Hashem LE, Curtin M, Delorme M, Goodall E, Yan K, Picketts DJ, Stalled replication forks within heterochromatin require ATRX for protection. Cell Death Dis. 2016 May 12;7:e2220
1	J:162581 Huillard E, Ziercher L, Blond O, Wong M, Deloulme JC, Souchelnytskyi S, Baudier J, Cochet C, Buchou T, Disruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalon. Mol Cell Biol. 2010 Jun;30(11):2737-49
1	J:235787 Ijaz T, Wakamiya M, Sun H, Recinos A 3rd, Tilton RG, Brasier AR, Generation and characterization of a novel transgenic mouse harboring conditional nuclear factor-kappa B/RelA knockout alleles. BMC Dev Biol. 2016 Sep 23;16(1):32
2	J:316818 Ito T, Osada A, Ohta M, Yokota K, Nishiyama A, Niikura Y, Tamura T, Sekita Y, Kimura T, SWI/SNF chromatin remodeling complex is required for initiation of sex-dependent differentiation in mouse germline. Sci Rep. 2021 Dec 15;11(1):24074
1	J:335423 Jia S, Wilbourne J, Crossen MJ, Zhao F, Morphogenesis of the female reproductive tract along antero-posterior and dorso-ventral axes is dependent on Amhr2+ mesenchyme in mice. Biol Reprod. 2022 Dec 10;107(6):1477-1489
1*	J:202252 Jones RL, Pepling ME, KIT signaling regulates primordial follicle formation in the neonatal mouse ovary. Dev Biol. 2013 Oct 1;382(1):186-97
1	J:199673 Kleppa L, Mari PO, Larsen E, Lien GF, Godon C, Theil AF, Nesse GJ, Wiksen H, Vermeulen W, Giglia-Mari G, Klungland A, Kinetics of endogenous mouse FEN1 in base excision repair. Nucleic Acids Res. 2012 Oct;40(18):9044-59
1	J:266268 Kowalchuk AM, Maurer KA, Shoja-Taheri F, Brown NL, Requirements for Neurogenin2 during mouse postnatal retinal neurogenesis. Dev Biol. 2018 Oct 15;442(2):220-235
3*	J:317362 Kuribayashi H, Baba Y, Iwagawa T, Arai E, Murakami A, Watanabe S, Roles of Nmnat1 in the survival of retinal progenitors through the regulation of pro-apoptotic gene expression via histone acetylation. Cell Death Dis. 2018 Aug 30;9(9):891
1	J:179805 Laird DJ, Altshuler-Keylin S, Kissner MD, Zhou X, Anderson KV, Ror2 enhances polarity and directional migration of primordial germ cells. PLoS Genet. 2011 Dec;7(12):e1002428
1	J:181272 Le TT, Conley KW, Mead TJ, Rowan S, Yutzey KE, Brown NL, Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development. Dev Dyn. 2012 Mar;241(3):493-504
1*	J:250161 Lee AJ, Polgar N, Napoli JA, Lui VH, Tamashiro KK, Fujimoto BA, Thompson KS, Fogelgren B, Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy. Sci Rep. 2016 Aug 11;6:31137
2*	J:301541 Lee SG, Kim N, Kim SM, Park IB, Kim H, Kim S, Kim BG, Hwang JM, Baek IJ, Gartner A, Park JH, Myung K, Ewing sarcoma protein promotes dissociation of poly(ADP-ribose) polymerase 1 from chromatin. EMBO Rep. 2020 Nov 5;21(11):e48676
1	J:152528 Lee Y, Katyal S, Li Y, El-Khamisy SF, Russell HR, Caldecott KW, McKinnon PJ, The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1. Nat Neurosci. 2009 Aug;12(8):973-80
1*	J:109158 Leu S, Ouyang P, Spatial and temporal expression profile of pinin during mouse development. Gene Expr Patterns. 2006 Aug;6(6):620-31
1*	J:303646 Li M, Zheng J, Li G, Lin Z, Li D, Liu D, Feng H, Cao D, Ng EHY, Li RHW, Han C, Yeung WSB, Chow LT, Wang H, Liu K, The male germline-specific protein MAPS is indispensable for pachynema progression and fertility. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2025421118
1*	J:302708 Liu HB, Muhammad T, Guo Y, Li MJ, Sha QQ, Zhang CX, Liu H, Zhao SG, Zhao H, Zhang H, Du YZ, Sun K, Liu K, Lu G, Guo XJ, Sha J, Fan HY, Gao F, Chen ZJ, RNA-Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator in Early Zygotic Genome Activation. Adv Sci (Weinh). 2019 Aug 7;6(15):1900295
3	J:294981 Liu X, Castle V, Taketo T, Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development. Cell Death Dis. 2019 Oct 17;10(11):790
1	J:268414 Liu Y, Fan C, Zhang Y, Yu X, Wu X, Zhang X, Zhao Q, Zhang H, Xie Q, Li M, Li X, Ding Q, Ying H, Li D, Zhang H, RIP1 kinase activity-dependent roles in embryonic development of Fadd-deficient mice. Cell Death Differ. 2017 Aug;24(8):1459-1469
1	J:255932 Mario Gonzalez-Meljem J, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Neda Mousavy-Gharavy S, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Pedro Martinez-Barbera J, Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma. Nat Commun. 2017 Nov 28;8(1):1819
5*	J:181599 Martin-Oliva D, Ferrer-Martin RM, Santos AM, Carrasco MC, Sierra A, Marin-Teva JL, Calvente R, Navascues J, Cuadros MA, Simultaneous cell death and upregulation of poly(ADP-ribose) polymerase-1 expression in early postnatal mouse retina. Invest Ophthalmol Vis Sci. 2011 Sep;52(10):7445-54
1	J:295965 Miesfeld JB, Ghiasvand NM, Marsh-Armstrong B, Marsh-Armstrong N, Miller EB, Zhang P, Manna SK, Zawadzki RJ, Brown NL, Glaser T, The Atoh7 remote enhancer provides transcriptional robustness during retinal ganglion cell development. Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21690-21700
1	J:184928 Miles DC, van den Bergen JA, Wakeling SI, Anderson RB, Sinclair AH, Western PS, The proto-oncogene Ret is required for male foetal germ cell survival. Dev Biol. 2012 May 1;365(1):101-9
2	J:42726 Nakayama H, Liu Y, Stifani S, Cross JC, Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway. Dev Genet. 1997;21(1):21-30
1	J:312383 Nelson MM, Hoff JD, Zeese ML, Corfas G, Poly (ADP-Ribose) Polymerase 1 Regulates Cajal-Retzius Cell Development and Neural Precursor Cell Adhesion. Front Cell Dev Biol. 2021;9:693595
6	J:306151 Nguyen DH, Soygur B, Peng SP, Malki S, Hu G, Laird DJ, Apoptosis in the fetal testis eliminates developmentally defective germ cell clones. Nat Cell Biol. 2020 Dec;22(12):1423-1435
2	J:152672 Ohsawa S, Hamada S, Asou H, Kuida K, Uchiyama Y, Yoshida H, Miura M, Caspase-9 activation revealed by semaphorin 7A cleavage is independent of apoptosis in the aged olfactory bulb. J Neurosci. 2009 Sep 9;29(36):11385-92
1	J:303303 Pan M, Yin Y, Wang X, Wang Q, Zhang L, Hu H, Wang C, Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation. Autophagy. 2020 Aug 2;:1-16
1	J:124128 Rajareddy S, Reddy P, Du C, Liu L, Jagarlamudi K, Tang W, Shen Y, Berthet C, Peng SL, Kaldis P, Liu K, p27kip1 (Cyclin-Dependent Kinase Inhibitor 1B) Controls Ovarian Development by Suppressing Follicle Endowment and Activation and Promoting Follicle Atresia in Mice. Mol Endocrinol. 2007 Sep;21(9):2189-202
2	J:154061 Riesenberg AN, Liu Z, Kopan R, Brown NL, Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci. 2009 Oct 14;29(41):12865-77
3	J:138714 Rowan S, Conley KW, Le TT, Donner AL, Maas RL, Brown NL, Notch signaling regulates growth and differentiation in the mammalian lens. Dev Biol. 2008 Sep 1;321(1):111-22
1	J:115283 Runyan C, Schaible K, Molyneaux K, Wang Z, Levin L, Wylie C, Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration. Development. 2006 Dec;133(24):4861-9
2	J:334114 Ruthig VA, Hatkevich T, Hardy J, Friedersdorf MB, Mayere C, Nef S, Keene JD, Capel B, The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromatin modifiers and translational machinery during late gestation. PLoS Genet. 2023 Mar;19(3):e1010656
1	J:276802 Sakashita A, Wakai T, Kawabata Y, Nishimura C, Sotomaru Y, Alavattam KG, Namekawa SH, Kono T, XY oocytes of sex-reversed females with a Sry mutation deviate from the normal developmental process beyond the mitotic stage. Biol Reprod. 2019 Mar 1;100(3):697-710
1	J:180791 Saravanamuthu SS, Le TT, Gao CY, Cojocaru RI, Pandiyan P, Liu C, Zhang J, Zelenka PS, Brown NL, Conditional ablation of the Notch2 receptor in the ocular lens. Dev Biol. 2012 Feb 15;362(2):219-29
5	J:77259 Schreiber V, Ame JC, Dolle P, Schultz I, Rinaldi B, Fraulob V, Menissier-de Murcia J, de Murcia G, Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1. J Biol Chem. 2002 Jun 21;277(25):23028-36
2	J:165253 Scott CE, Wynn SL, Sesay A, Cruz C, Cheung M, Gomez Gaviro MV, Booth S, Gao B, Cheah KS, Lovell-Badge R, Briscoe J, SOX9 induces and maintains neural stem cells. Nat Neurosci. 2010 Oct;13(10):1181-9
1*	J:234716 Segura I, Lange C, Knevels E, Moskalyuk A, Pulizzi R, Eelen G, Chaze T, Tudor C, Boulegue C, Holt M, Daelemans D, Matondo M, Ghesquiere B, Giugliano M, Ruiz de Almodovar C, Dewerchin M, Carmeliet P, The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A. Cell Rep. 2016 Mar 22;14(11):2653-67
1	J:304006 Shi X, Lim Y, Myers AK, Stallings BL, Mccoy A, Zeiger J, Scheck J, Cho G, Marsh ED, Mirzaa GM, Tao T, Golden JA, PIK3R2/Pik3r2 Activating Mutations Result in Brain Overgrowth and EEG Changes. Ann Neurol. 2020 Dec;88(6):1077-1094
4	J:346121 Shu J, Yan S, Ju C, Chen L, Liang M, Wang C, Huang K, PARP1 Promotes Heart Regeneration and Cardiomyocyte Proliferation. Int J Biol Sci. 2024;20(5):1602-1616
1	J:313675 Soygur B, Jaszczak RG, Fries A, Nguyen DH, Malki S, Hu G, Demir N, Arora R, Laird DJ, Intercellular bridges coordinate the transition from pluripotency to meiosis in mouse fetal oocytes. Sci Adv. 2021 Apr;7(15)
1	J:118190 Sugo N, Niimi N, Aratani Y, Masutani M, Suzuki H, Koyama H, Decreased PARP-1 levels accelerate embryonic lethality but attenuate neuronal apoptosis in DNA polymerase beta-deficient mice. Biochem Biophys Res Commun. 2007 Mar 16;354(3):656-61
1	J:101924 Tang LS, Wlodarczyk BJ, Santillano DR, Miranda RC, Finnell RH, Developmental consequences of abnormal folate transport during murine heart morphogenesis. Birth Defects Res A Clin Mol Teratol. 2004 Jul;70(7):449-58
1	J:144502 Taniguchi N, Carames B, Ronfani L, Ulmer U, Komiya S, Bianchi ME, Lotz M, Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis. Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1181-6
2*	J:109514 Vats KR, Ishwad C, Singla I, Vats A, Ferrell R, Ellis D, Moritz M, Surti U, Jayakar P, Frederick DR, Vats AN, A locus for renal malformations including vesico-ureteric reflux on chromosome 13q33-34. J Am Soc Nephrol. 2006 Apr;17(4):1158-67
4	J:115402 Vemuri MC, Schiller E, Naegele JR, Elevated DNA double strand breaks and apoptosis in the CNS of scid mutant mice. Cell Death Differ. 2001 Mar;8(3):245-55
1	J:284292 Wang B, Zhang Y, Dong H, Gong S, Wei B, Luo M, Wang H, Wu X, Liu W, Xu X, Zheng Y, Sun M, Loss of Tctn3 causes neuronal apoptosis and neural tube defects in mice. Cell Death Dis. 2018 May 1;9(5):520
1	J:351707 Wen C, Cao L, Wang S, Xu W, Yu Y, Zhao S, Yang F, Chen ZJ, Zhao S, Yang Y, Qin Y, MCM8 interacts with DDX5 to promote R-loop resolution. EMBO J. 2024 Jul;43(14):3044-3071
1*	J:344364 Wilbourne J, Jia S, Fogarty A, Takaku M, Zhao F, Crucial Roles of the Mesenchymal Androgen Receptor in Wolffian Duct Development. Endocrinology. 2023 Dec 23;165(2)
1	J:301042 Wright D, Kiso M, Saga Y, Genetic and structural analysis of the in vivo functional redundancy between murine NANOS2 and NANOS3. Development. 2021 Jan 11;148(1):dev191916
1	J:311882 Xu D, Jin T, Zhu H, Chen H, Ofengeim D, Zou C, Mifflin L, Pan L, Amin P, Li W, Shan B, Naito MG, Meng H, Li Y, Pan H, Aron L, Adiconis X, Levin JZ, Yankner BA, Yuan J, TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging. Cell. 2018 Sep 6;174(6):1477-1491.e19
1	J:339060 Xu W, Yang Y, Yu Y, Wen C, Zhao S, Cao L, Zhao S, Qin Y, Chen ZJ, FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells. BMC Biol. 2023 Aug 15;21(1):174
1	J:327430 Yang Y, Xu W, Gao F, Wen C, Zhao S, Yu Y, Jiao W, Mi X, Qin Y, Chen ZJ, Zhao S, Transcription-replication conflicts in primordial germ cells necessitate the Fanconi anemia pathway to safeguard genome stability. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2203208119
1	J:223139 Ye J, Beetz N, O'Keeffe S, Tapia JC, Macpherson L, Chen WV, Bassel-Duby R, Olson EN, Maniatis T, hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):E3020-9
2*	J:281166 Zhang X, Zhang H, Xu C, Li X, Li M, Wu X, Pu W, Zhou B, Wang H, Li D, Ding Q, Ying H, Wang H, Zhang H, Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis. Nat Commun. 2019 Sep 13;10(1):4158