Gene Expression Literature Summary

• Symbol: Trpv1
• Name: transient receptor potential cation channel, subfamily V, member 1
• ID: MGI:1341787

48 matching records from 48 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	P
Immunohistochemistry (section)		1		1	1	1		1	1	1		1	2	1	2		1	1	2	19
In situ RNA (section)	1		1		3		1		2		3		3		1				2	14
In situ reporter (knock in)					1		1		1		1			2	1			2		3
Western blot																1				4
RT-PCR			1		2		1		1		2		1	1	1	1		1	1	10

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Trpv1  transient receptor potential cation channel, subfamily V, member 1   (Synonyms: capsaicin receptor, OTRPC1, Vr1, VR-1)
Results	Reference
3*	J:161879 Asai Y, Holt JR, Geleoc GS, A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea. J Assoc Res Otolaryngol. 2010 Mar;11(1):27-37
1	J:178481 Bachy I, Franck MC, Li L, Abdo H, Pattyn A, Ernfors P, The transcription factor Cux2 marks development of an A-delta sublineage of TrkA sensory neurons. Dev Biol. 2011 Dec 1;360(1):77-86
1	J:326957 Cao Z, Huang C, Lu F, Jiang X, Hu Y, Cao C, Liu Z, Meis1 Regulates Nociceptor Development and Behavioral Response to Tactile Stimuli. Front Mol Neurosci. 2022;15:901466
7	J:174523 Cavanaugh DJ, Chesler AT, Braz JM, Shah NM, Julius D, Basbaum AI, Restriction of transient receptor potential vanilloid-1 to the peptidergic subset of primary afferent neurons follows its developmental downregulation in nonpeptidergic neurons. J Neurosci. 2011 Jul 13;31(28):10119-27
1	J:106971 Chen CL, Broom DC, Liu Y, de Nooij JC, Li Z, Cen C, Samad OA, Jessell TM, Woolf CJ, Ma Q, Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain. Neuron. 2006 Feb 2;49(3):365-77
1*	J:187163 Chen TR, Wang P, Carroll LK, Zhang YJ, Han BX, Wang F, Generation and characterization of Tmeff2 mutant mice. Biochem Biophys Res Commun. 2012 Aug 24;425(2):189-94
1	J:70560 Chen Z, Rebelo S, White F, Malmberg AB, Baba H, Lima D, Woolf CJ, Basbaum AI, Anderson DJ, The paired homeodomain protein drg11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord. Neuron. 2001 Jul 19;31(1):59-73
1	J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400
6	J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014
1*	J:308929 De Vincenti AP, Alsina FC, Ferrero Restelli F, Hedman H, Ledda F, Paratcha G, Lrig1 and Lrig3 cooperate to control Ret receptor signaling, sensory axonal growth and epidermal innervation. Development. 2021 Aug 15;148(16):dev197020
1	J:353354 Desiderio S, Schwaller F, Tartour K, Padmanabhan K, Lewin GR, Carroll P, Marmigere F, Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2. Elife. 2024 Feb 22;12
1	J:283226 Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, Fletcher EV, Vanwelden T, Schmidt BZ, Henningfeld KA, Pieler T, Woods CG, Nagy V, Verfaillie C, Bellefroid EJ, Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA. Cell Rep. 2019 Mar 26;26(13):3522-3536.e5
1	J:331106 Dietrich S, Company C, Song K, Lowenstein ED, Riedel L, Birchmeier C, Gargiulo G, Zampieri N, Molecular identity of proprioceptor subtypes innervating different muscle groups in mice. Nat Commun. 2022 Nov 11;13(1):6867
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
2	J:309996 Dumas S, Wallen-Mackenzie A, Developmental Co-expression of Vglut2 and Nurr1 in a Mes-Di-Encephalic Continuum Preceeds Dopamine and Glutamate Neuron Specification. Front Cell Dev Biol. 2019;7:307
1*	J:136996 Elg S, Marmigere F, Mattsson JP, Ernfors P, Cellular subtype distribution and developmental regulation of TRPC channel members in the mouse dorsal root ganglion. J Comp Neurol. 2007 Jul 1;503(1):35-46
9	J:102994 Funakoshi K, Nakano M, Atobe Y, Goris RC, Kadota T, Yazama F, Differential development of TRPV1-expressing sensory nerves in peripheral organs. Cell Tissue Res. 2006 Jan;323(1):27-41
3	J:114546 Funakoshi K, Nakano M, Atobe Y, Kadota T, Goris RC, Prenatal development of transient receptor potential vanilloid 1-expressing primary sensory projections to sacral autonomic preganglionic neurons. Neurosci Lett. 2006 Oct 30;407(3):230-3
1	J:210892 Gorokhova S, Gaillard S, Urien L, Malapert P, Legha W, Baronian G, Desvignes JP, Alonso S, Moqrich A, Uncoupling of molecular maturation from peripheral target innervation in nociceptors expressing a chimeric TrkA/TrkC receptor. PLoS Genet. 2014 Feb;10(2):e1004081
3*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2	J:306108 Karpinski BA, Maynard TM, Bryan CA, Yitsege G, Horvath A, Lee NH, Moody SA, LaMantia AS, Selective disruption of trigeminal sensory neurogenesis and differentiation in a mouse model of 22q11.2 deletion syndrome. Dis Model Mech. 2022 Feb 1;15(2):dmm047357
2*	J:145300 Kim AY, Tang Z, Liu Q, Patel KN, Maag D, Geng Y, Dong X, Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1. Cell. 2008 May 2;133(3):475-85
2	J:304297 Landy MA, Goyal M, Casey KM, Liu C, Lai HC, Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation. Cell Rep. 2021 Mar 30;34(13):108913
3	J:148796 Lechner SG, Frenzel H, Wang R, Lewin GR, Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development. EMBO J. 2009 May 20;28(10):1479-91
1	J:285409 Li Y, Jiao J, Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia. Sci Adv. 2020 Jan;6(1):eaay6350
2*	J:186470 Lopes C, Liu Z, Xu Y, Ma Q, Tlx3 and runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors. J Neurosci. 2012 Jul 11;32(28):9706-15
1	J:221586 Lou S, Pan X, Huang T, Duan B, Yang FC, Yang J, Xiong M, Liu Y, Ma Q, Incoherent feed-forward regulatory loops control segregation of C-mechanoreceptors, nociceptors, and pruriceptors. J Neurosci. 2015 Apr 1;35(13):5317-29
1	J:337785 Lowenstein ED, Ruffault PL, Misios A, Osman KL, Li H, Greenberg RS, Thompson R, Song K, Dietrich S, Li X, Vladimirov N, Woehler A, Brunet JF, Zampieri N, Kuhn R, Liberles SD, Jia S, Lewin GR, Rajewsky N, Lever TE, Birchmeier C, Prox2 and Runx3 vagal sensory neurons regulate esophageal motility. Neuron. 2023 May 10;
1*	J:126484 Luo W, Wickramasinghe SR, Savitt JM, Griffin JW, Dawson TM, Ginty DD, A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons. Neuron. 2007 Jun 7;54(5):739-54
1	J:56292 Ma Q, Fode C, Guillemot F, Anderson DJ, Neurogenin1 and neurogenin2 control two distinct waves of neurogenesis in developing dorsal root ganglia. Genes Dev. 1999 Jul 1;13(13):1717-28
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
2	J:227268 Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Bjorklund P, Mackie K, Di Marzo V, Hokfelt TG, Dobrzyn A, Harkany T, Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6185-94
1	J:97000 Morikawa Y, Tamura S, Minehata K, Donovan PJ, Miyajima A, Senba E, Essential function of oncostatin m in nociceptive neurons of dorsal root ganglia. J Neurosci. 2004 Feb 25;24(8):1941-7
5*	J:278353 Nakazawa Y, Donaldson PJ, Petrova RS, Verification and spatial mapping of TRPV1 and TRPV4 expression in the embryonic and adult mouse lens. Exp Eye Res. 2019 Jun 20;186:107707
1	J:76188 Peier AM, Moqrich A, Hergarden AC, Reeve AJ, Andersson DA, Story GM, Earley TJ, Dragoni I, McIntyre P, Bevan S, Patapoutian A, A TRP channel that senses cold stimuli and menthol. Cell. 2002 Mar 8;108(5):705-15
3*	J:225328 Ren AJ, Wang K, Zhang H, Liu A, Ma X, Liang Q, Cao D, Wood JN, He DZ, Ding YQ, Yuan WJ, Xie Z, Zhang WJ, ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons. Nat Commun. 2014;5:4984
2	J:327897 Rios AS, Paula De Vincenti A, Casadei M, Aquino JB, Brumovsky PR, Paratcha G, Ledda F, Etv4 regulates nociception by controlling peptidergic sensory neuron development and peripheral tissue innervation. Development. 2022 Aug 15;149(16):dev200583
6	J:159386 Shibasaki K, Murayama N, Ono K, Ishizaki Y, Tominaga M, TRPV2 enhances axon outgrowth through its activation by membrane stretch in developing sensory and motor neurons. J Neurosci. 2010 Mar 31;30(13):4601-12
1	J:123606 Shields SD, Mazario J, Skinner K, Basbaum AI, Anatomical and functional analysis of aquaporin 1, a water channel in primary afferent neurons. Pain. 2007 Sep;131(1-2):8-20
1	J:354852 Singh K, Jayaram M, Hanumantharaju A, Tonissoo T, Jagomae T, Mikheim K, Muthuraman S, Gilbert SF, Plaas M, Schafer MKE, Innos J, Lillevali K, Philips MA, Vasar E, The IgLON family of cell adhesion molecules expressed in developing neural circuits ensure the proper functioning of the sensory system in mice. Sci Rep. 2024 Sep 30;14(1):22593
3	J:308698 Smith-Anttila CJA, Morrison V, Keast JR, Spatiotemporal mapping of sensory and motor innervation of the embryonic and postnatal mouse urinary bladder. Dev Biol. 2021 Aug;476:18-32
3	J:164572 Sun X, Xie H, Yang J, Wang H, Bradshaw HB, Dey SK, Endocannabinoid signaling directs differentiation of trophoblast cell lineages and placentation. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16887-92
5	J:95250 Tamura S, Morikawa Y, Senba E, TRPV2, a capsaicin receptor homologue, is expressed predominantly in the neurotrophin-3-dependent subpopulation of primary sensory neurons. Neuroscience. 2005;130(1):223-8
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:108959 Villeda SA, Akopians AL, Babayan AH, Basbaum AI, Phelps PE, Absence of Reelin results in altered nociception and aberrant neuronal positioning in the dorsal spinal cord. Neuroscience. 2006;139(4):1385-96
1	J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45
1*	J:244828 Wu J, Peng S, Wu R, Hao Y, Ji G, Yuan Z, Generation of Calhm1 knockout mouse and characterization of calhm1 gene expression. Protein Cell. 2012 Jun;3(6):470-80
1	J:266090 Xia W, Su L, Jiao J, Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress. J Cell Biol. 2018 Oct 1;217(10):3464-3479