Gene Expression Literature Summary

• Symbol: Robo3
• Name: roundabout guidance receptor 3
• ID: MGI:1343102

116 matching records from 116 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E18	E18.5	E	P
Immunohistochemistry (section)		1	1	4	12	5	31	2	19	5	11	1	6		5	1	5			3	3	1
In situ RNA (section)	1		1	1	4		13		18	1	9	3	11	1	8	2	5	1	1	4	1	8
Immunohistochemistry (whole mount)		1	1	2	2	4	2	2	5	2	1	1	2	1	2	2	2		1			2
In situ RNA (whole mount)	2		3	1	1	1	1		4	1	3	1	4	1	4		2	1		2	1
In situ reporter (knock in)							3		1		2		4		2		1
Northern blot					1		1		1		1											1
Western blot					1	1	2		2		1		1									4
RT-PCR					3		4		2		3		1		1							2
cDNA clones							1						1									1
Primer Extension							1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Robo3  roundabout guidance receptor 3   (Synonyms: Rbig1, Rig-1, Rig1, Robo3a, Robo3b)
Results	Reference
1	J:273860 Andreu-Cervera A, Anselme I, Karam A, Laclef C, Catala M, Schneider-Maunoury S, The Ciliopathy Gene Ftm/Rpgrip1l Controls Mouse Forebrain Patterning via Region-Specific Modulation of Hedgehog/Gli Signaling. J Neurosci. 2019 Mar 27;39(13):2398-2415
1	J:109478 Andrews W, Liapi A, Plachez C, Camurri L, Zhang J, Mori S, Murakami F, Parnavelas JG, Sundaresan V, Richards LJ, Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain. Development. 2006 Jun;133(11):2243-52
1	J:178481 Bachy I, Franck MC, Li L, Abdo H, Pattyn A, Ernfors P, The transcription factor Cux2 marks development of an A-delta sublineage of TrkA sensory neurons. Dev Biol. 2011 Dec 1;360(1):77-86
6*	J:148786 Barber M, Di Meglio T, Andrews WD, Hernandez-Miranda LR, Murakami F, Chedotal A, Parnavelas JG, The role of Robo3 in the development of cortical interneurons. Cereb Cortex. 2009 Jul;19 Suppl 1:i22-31
3	J:218756 Belle M, Godefroy D, Dominici C, Heitz-Marchaland C, Zelina P, Hellal F, Bradke F, Chedotal A, A simple method for 3D analysis of immunolabeled axonal tracts in a transparent nervous system. Cell Rep. 2014 Nov 20;9(4):1191-201
4*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
1	J:165285 Bouvier J, Thoby-Brisson M, Renier N, Dubreuil V, Ericson J, Champagnat J, Pierani A, Chedotal A, Fortin G, Hindbrain interneurons and axon guidance signaling critical for breathing. Nat Neurosci. 2010 Sep;13(9):1066-74
1*	J:104261 Camurri L, Mambetisaeva E, Davies D, Parnavelas J, Sundaresan V, Andrews W, Evidence for the existence of two Robo3 isoforms with divergent biochemical properties. Mol Cell Neurosci. 2005 Dec;30(4):485-93
10*	J:87380 Camurri L, Mambetisaeva E, Sundaresan V, Rig-1 a new member of Robo family genes exhibits distinct pattern of expression during mouse development. Gene Expr Patterns. 2004 Jan;4(1):99-103
2	J:187711 Cariboni A, Andrews WD, Memi F, Ypsilanti AR, Zelina P, Chedotal A, Parnavelas JG, Slit2 and Robo3 modulate the migration of GnRH-secreting neurons. Development. 2012 Sep;139(18):3326-31
1	J:224508 Chatterjee M, Guo Q, Weber S, Scholpp S, Li JY, Pax6 regulates the formation of the habenular nuclei by controlling the temporospatial expression of Shh in the diencephalon in vertebrates. BMC Biol. 2014;12:13
4	J:103829 Chen B, Schaevitz LR, McConnell SK, Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex. Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17184-9
12*	J:145298 Chen Z, Gore BB, Long H, Ma L, Tessier-Lavigne M, Alternative splicing of the Robo3 axon guidance receptor governs the midline switch from attraction to repulsion. Neuron. 2008 May 8;58(3):325-32
2*	J:124331 Cho JH, Lepine M, Andrews W, Parnavelas J, Cloutier JF, Requirement for Slit-1 and Robo-2 in zonal segregation of olfactory sensory neuron axons in the main olfactory bulb. J Neurosci. 2007 Aug 22;27(34):9094-104
1	J:340669 Choi JS, Ayupe AC, Beckedorff F, Catanuto P, McCartan R, Levay K, Park KK, Single-nucleus RNA sequencing of developing superior colliculus identifies neuronal diversity and candidate mediators of circuit assembly. Cell Rep. 2023 Aug 24;42(9):113037
3	J:198412 Colak D, Ji SJ, Porse BT, Jaffrey SR, Regulation of axon guidance by compartmentalized nonsense-mediated mRNA decay. Cell. 2013 Jun 6;153(6):1252-65
1	J:313341 Comer JD, Pan FC, Willet SG, Haldipur P, Millen KJ, Wright CV, Kaltschmidt JA, Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3. Front Neural Circuits. 2015;9:36
3*	J:308673 Company V, Andreu-Cervera A, Madrigal MP, Andres B, Almagro-Garcia F, Chedotal A, Lopez-Bendito G, Martinez S, Echevarria D, Moreno-Bravo JA, Puelles E, Netrin 1-Mediated Role of the Substantia Nigra Pars Compacta and Ventral Tegmental Area in the Guidance of the Medial Habenular Axons. Front Cell Dev Biol. 2021;9:682067
1	J:312488 Company V, Moreno-Cerda A, Andreu-Cervera A, Murcia-Ramon R, Almagro-Garcia F, Echevarria D, Martinez S, Puelles E, Wnt1 Role in the Development of the Habenula and the Fasciculus Retroflexus. Front Cell Dev Biol. 2021;9:755729
3	J:336857 Dailey-Krempel B, Martin AL, Jo HN, Junge HJ, Chen Z, A tug of war between DCC and ROBO1 signaling during commissural axon guidance. Cell Rep. 2023 May 30;42(5):112455
1	J:319391 Decourtye L, McCallum-Loudeac JA, Zellhuber-McMillan S, Young E, Sircombe KJ, Wilson MJ, Characterization of a novel Lbx1 mouse loss of function strain. Differentiation. 2021 Dec 9;123:30-41
1*	J:103453 Denaxa M, Kyriakopoulou K, Theodorakis K, Trichas G, Vidaki M, Takeda Y, Watanabe K, Karagogeos D, The adhesion molecule TAG-1 is required for proper migration of the superficial migratory stream in the medulla but not of cortical interneurons. Dev Biol. 2005 Dec 1;288(1):87-99
1	J:344351 Deska-Gauthier D, Borowska-Fielding J, Jones C, Zhang H, MacKay CS, Michail R, Bennett LA, Bikoff JB, Zhang Y, Embryonic temporal-spatial delineation of excitatory spinal V3 interneuron diversity. Cell Rep. 2023 Dec 29;43(1):113635
1	J:197162 Di Bonito M, Narita Y, Avallone B, Sequino L, Mancuso M, Andolfi G, Franze AM, Puelles L, Rijli FM, Studer M, Assembly of the auditory circuitry by a Hox genetic network in the mouse brainstem. PLoS Genet. 2013;9(2):e1003249
2	J:137616 Di Meglio T, Nguyen-Ba-Charvet KT, Tessier-Lavigne M, Sotelo C, Chedotal A, Molecular mechanisms controlling midline crossing by precerebellar neurons. J Neurosci. 2008 Jun 18;28(25):6285-94
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:181907 Ding Q, Joshi PS, Xie ZH, Xiang M, Gan L, BARHL2 transcription factor regulates the ipsilateral/contralateral subtype divergence in postmitotic dI1 neurons of the developing spinal cord. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1566-71
4	J:249067 Dominici C, Moreno-Bravo JA, Puiggros SR, Rappeneau Q, Rama N, Vieugue P, Bernet A, Mehlen P, Chedotal A, Floor-plate-derived netrin-1 is dispensable for commissural axon guidance. Nature. 2017 May 18;545(7654):350-354
3	J:253971 Dominici C, Rappeneau Q, Zelina P, Fouquet S, Chedotal A, Non-cell autonomous control of precerebellar neuron migration by Slit and Robo proteins. Development. 2018 Jan 17;145(2):dev150375
1	J:314102 Ducuing H, Gardette T, Pignata A, Kindbeiter K, Bozon M, Thoumine O, Delloye-Bourgeois C, Tauszig-Delamasure S, Castellani V, SlitC-PlexinA1 mediates iterative inhibition for orderly passage of spinal commissural axons through the floor plate. Elife. 2020 Dec 21;9:e63205
1	J:207512 Escalante A, Murillo B, Morenilla-Palao C, Klar A, Herrera E, Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS. Neuron. 2013 Dec 18;80(6):1392-406
1	J:283254 Ferent J, Constable S, Gigante ED, Yam PT, Mariani LE, Legue E, Liem KF Jr, Caspary T, Charron F, The Ciliary Protein Arl13b Functions Outside of the Primary Cilium in Shh-Mediated Axon Guidance. Cell Rep. 2019 Dec 10;29(11):3356-3366.e3
1	J:278143 Ferent J, Giguere F, Jolicoeur C, Morin S, Michaud JF, Makihara S, Yam PT, Cayouette M, Charron F, Boc Acts via Numb as a Shh-Dependent Endocytic Platform for Ptch1 Internalization and Shh-Mediated Axon Guidance. Neuron. 2019 Jun 19;102(6):1157-1171.e5
25*	J:278498 Friocourt F, Kozulin P, Belle M, Suarez R, Di-Poi N, Richards LJ, Giacobini P, Chedotal A, Shared and differential features of Robo3 expression pattern in amniotes. J Comp Neurol. 2019 Aug 15;527(12):2009-2029
4	J:139385 Geisen MJ, Di Meglio T, Pasqualetti M, Ducret S, Brunet JF, Chedotal A, Rijli FM, Hox paralog group 2 genes control the migration of mouse pontine neurons through slit-robo signaling. PLoS Biol. 2008 Jun 10;6(6):e142
2*	J:352718 Gorla M, Chaudhari K, Hale M, Potter C, Bashaw GJ, A Nedd4 E3 Ubiquitin Ligase Pathway Inhibits Robo1 Repulsion and Promotes Commissural Axon Guidance across the Midline. J Neurosci. 2022 Oct 5;42(40):7547-7561
3	J:290598 Gorla M, Santiago C, Chaudhari K, Layman AAK, Oliver PM, Bashaw GJ, Ndfip Proteins Target Robo Receptors for Degradation and Allow Commissural Axons to Cross the Midline in the Developing Spinal Cord. Cell Rep. 2019 Mar 19;26(12):3298-3312.e4
1*	J:229257 Gu Z, Imai F, Kim IJ, Fujita H, Katayama Ki, Mori K, Yoshihara Y, Yoshida Y, Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2*	J:331142 Han P, She Y, Yang Z, Zhuang M, Wang Q, Luo X, Yin C, Zhu J, Jaffrey SR, Ji SJ, Cbln1 regulates axon growth and guidance in multiple neural regions. PLoS Biol. 2022 Nov;20(11):e3001853
2	J:186283 Hashimoto M, Ito R, Kitamura N, Namba K, Hisano Y, Epha4 controls the midline crossing and contralateral axonal projections of inferior olive neurons. J Comp Neurol. 2012 Jun 1;520(8):1702-20
1	J:227404 Hernandez-Enriquez B, Wu Z, Martinez E, Olsen O, Kaprielian Z, Maness PF, Yoshida Y, Tessier-Lavigne M, Tran TS, Floor plate-derived neuropilin-2 functions as a secreted semaphorin sink to facilitate commissural axon midline crossing. Genes Dev. 2015 Dec 15;29(24):2617-32
1	J:166771 Holz A, Kollmus H, Ryge J, Niederkofler V, Dias J, Ericson J, Stoeckli ET, Kiehn O, Arnold HH, The transcription factors Nkx2.2 and Nkx2.9 play a novel role in floor plate development and commissural axon guidance. Development. 2010 Dec;137(24):4249-60
2	J:208415 Inamata Y, Shirasaki R, Dbx1 triggers crucial molecular programs required for midline crossing by midbrain commissural axons. Development. 2014 Mar;141(6):1260-71
3	J:162558 Jaworski A, Long H, Tessier-Lavigne M, Collaborative and specialized functions of Robo1 and Robo2 in spinal commissural axon guidance. J Neurosci. 2010 Jul 14;30(28):9445-53
2*	J:227045 Jaworski A, Tom I, Tong RK, Gildea HK, Koch AW, Gonzalez LC, Tessier-Lavigne M, Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2. Science. 2015 Nov 20;350(6263):961-5
2	J:279776 Johnson V, Junge HJ, Chen Z, Temporal regulation of axonal repulsion by alternative splicing of a conserved microexon in mammalian Robo1 and Robo2. Elife. 2019 Aug 8;8:e46042
1	J:133680 Jones CA, London NR, Chen H, Park KW, Sauvaget D, Stockton RA, Wythe JD, Suh W, Larrieu-Lahargue F, Mukouyama YS, Lindblom P, Seth P, Frias A, Nishiya N, Ginsberg MH, Gerhardt H, Zhang K, Li DY, Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability. Nat Med. 2008 Apr;14(4):448-53
1*	J:119301 Kadison SR, Murakami F, Matise MP, Kaprielian Z, The role of floor plate contact in the elaboration of contralateral commissural projections within the embryonic mouse spinal cord. Dev Biol. 2006 Aug 15;296(2):499-513
1	J:213451 Karpinski BA, Maynard TM, Fralish MS, Nuwayhid S, Zohn IE, Moody SA, LaMantia AS, Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome. Dis Model Mech. 2014 Feb;7(2):245-57
2	J:169455 Kim D, Ackerman SL, The UNC5C netrin receptor regulates dorsal guidance of mouse hindbrain axons. J Neurosci. 2011 Feb 9;31(6):2167-79
1*	J:272623 Kinoshita-Kawada M, Hasegawa H, Hongu T, Yanagi S, Kanaho Y, Masai I, Mishima T, Chen X, Tsuboi Y, Rao Y, Yuasa-Kawada J, Wu JY, A crucial role for Arf6 in the response of commissural axons to Slit. Development. 2019 Feb 4;146(3):dev172106
1	J:266268 Kowalchuk AM, Maurer KA, Shoja-Taheri F, Brown NL, Requirements for Neurogenin2 during mouse postnatal retinal neurogenesis. Dev Biol. 2018 Oct 15;442(2):220-235
7	J:163240 Kuwako K, Kakumoto K, Imai T, Igarashi M, Hamakubo T, Sakakibara S, Tessier-Lavigne M, Okano HJ, Okano H, Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression. Neuron. 2010 Aug 12;67(3):407-21
3	J:208339 Laumonnerie C, Da Silva RV, Kania A, Wilson SI, Netrin 1 and Dcc signalling are required for confinement of central axons within the central nervous system. Development. 2014 Feb;141(3):594-603
6	J:272124 Laumonnerie C, Tong YG, Alstermark H, Wilson SI, Commissural axonal corridors instruct neuronal migration in the mouse spinal cord. Nat Commun. 2015 May 11;6:7028
2	J:241012 Lee M, Yoon J, Song H, Lee B, Lam DT, Yoon J, Baek K, Clevers H, Jeong Y, Tcf7l2 plays crucial roles in forebrain development through regulation of thalamic and habenular neuron identity and connectivity. Dev Biol. 2017 Apr 01;424(1):62-76
5	J:234106 Leggere JC, Saito Y, Darnell RB, Tessier-Lavigne M, Junge HJ, Chen Z, NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord. Elife. 2016;5:e14264
1	J:227021 Mallika C, Guo Q, Li JY, Gbx2 is essential for maintaining thalamic neuron identity and repressing habenular characters in the developing thalamus. Dev Biol. 2015 Nov 1;407(1):26-39
2*	J:97466 Mambetisaeva ET, Andrews W, Camurri L, Annan A, Sundaresan V, Robo family of proteins exhibit differential expression in mouse spinal cord and Robo-Slit interaction is required for midline crossing in vertebrate spinal cord. Dev Dyn. 2005 May;233(1):41-51
1	J:328992 Manuel M, Tan KB, Kozic Z, Molinek M, Marcos TS, Razak MFA, Dobolyi D, Dobie R, Henderson BEP, Henderson NC, Chan WK, Daw MI, Mason JO, Price DJ, Pax6 limits the competence of developing cerebral cortical cells to respond to inductive intercellular signals. PLoS Biol. 2022 Sep;20(9):e3001563
1	J:154253 Marcos S, Backer S, Causeret F, Tessier-Lavigne M, Bloch-Gallego E, Differential roles of Netrin-1 and its receptor DCC in inferior olivary neuron migration. Mol Cell Neurosci. 2009 Aug;41(4):429-39
13	J:91469 Marillat V, Sabatier C, Failli V, Matsunaga E, Sotelo C, Tessier-Lavigne M, Chedotal A, The slit receptor Rig-1/Robo3 controls midline crossing by hindbrain precerebellar neurons and axons. Neuron. 2004 Jul 8;43(1):69-79
2	J:104419 Marion JF, Yang C, Caqueret A, Boucher F, Michaud JL, Sim1 and Sim2 are required for the correct targeting of mammillary body axons. Development. 2005 Dec;132(24):5527-37
4	J:293331 Martinez-Chavez E, Scheerer C, Wizenmann A, Blaess S, The zinc-finger transcription factor GLI3 is a regulator of precerebellar neuronal migration. Development. 2018 Dec 17;145(24):dev166033
9	J:348685 Masuda A, Nishida K, Ajima R, Saga Y, Bakhtan M, Klar A, Hirata T, Zhu Y, A global gene regulatory program and its region-specific regulator partition neurons into commissural and ipsilateral projection types. Sci Adv. 2024 May 24;10(21):eadk2149
3*	J:166534 Medioni C, Bertrand N, Mesbah K, Hudry B, Dupays L, Wolstein O, Washkowitz AJ, Papaioannou VE, Mohun TJ, Harvey RP, Zaffran S, Expression of Slit and Robo genes in the developing mouse heart. Dev Dyn. 2010 Dec;239(12):3303-11
1	J:351037 Mehta K, Daghsni M, Raeisossadati R, Xu Z, Davis E, Naidich A, Wang B, Tao S, Pi S, Chen W, Kostka D, Liu S, Gross JM, Kuwajima T, Aldiri I, A cis-regulatory module underlies retinal ganglion cell genesis and axonogenesis. Cell Rep. 2024 Jun 25;43(6):114291
4	J:191773 Mirza R, Kivrak BG, Erzurumlu RS, Cooperative slit and netrin signaling in contralateralization of the mouse trigeminothalamic pathway. J Comp Neurol. 2013 Feb 1;521(2):312-25
1	J:212863 Mommersteeg MT, Andrews WD, Ypsilanti AR, Zelina P, Yeh ML, Norden J, Kispert A, Chedotal A, Christoffels VM, Parnavelas JG, Slit-roundabout signaling regulates the development of the cardiac systemic venous return and pericardium. Circ Res. 2013 Feb 1;112(3):465-75
2	J:316285 Moreno-Bravo JA, Martinez-Lopez JE, Madrigal MP, Kim M, Mastick GS, Lopez-Bendito G, Martinez S, Puelles E, Developmental guidance of the retroflex tract at its bending point involves Robo1-Slit2-mediated floor plate repulsion. Brain Struct Funct. 2016 Jan;221(1):665-78
3	J:253980 Moreno-Bravo JA, Roig Puiggros S, Blockus H, Dominici C, Zelina P, Mehlen P, Chedotal A, Commissural neurons transgress the CNS/PNS boundary in absence of ventricular zone-derived netrin 1. Development. 2018 Jan 17;145(2):dev159400
4	J:272917 Moreno-Bravo JA, Roig Puiggros S, Mehlen P, Chedotal A, Synergistic Activity of Floor-Plate- and Ventricular-Zone-Derived Netrin-1 in Spinal Cord Commissural Axon Guidance. Neuron. 2019 Feb 20;101(4):625-634.e3
1	J:156992 Nawabi H, Briancon-Marjollet A, Clark C, Sanyas I, Takamatsu H, Okuno T, Kumanogoh A, Bozon M, Takeshima K, Yoshida Y, Moret F, Abouzid K, Castellani V, A midline switch of receptor processing regulates commissural axon guidance in vertebrates. Genes Dev. 2010 Feb 15;24(4):396-410
1	J:115577 Okada A, Charron F, Morin S, Shin DS, Wong K, Fabre PJ, Tessier-Lavigne M, McConnell SK, Boc is a receptor for sonic hedgehog in the guidance of commissural axons. Nature. 2006 Nov 16;444(7117):369-73
1*	J:286386 Pak JS, DeLoughery ZJ, Wang J, Acharya N, Park Y, Jaworski A, Ozkan E, NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance. Nat Commun. 2020 Mar 20;11(1):1489
1*	J:259672 Peng J, Ferent J, Li Q, Liu M, Da Silva RV, Zeilhofer HU, Kania A, Zhang Y, Charron F, Loss of Dcc in the spinal cord is sufficient to cause a deficit in lateralized motor control and the switch to a hopping gait. Dev Dyn. 2018 Apr;247(4):620-629
3	J:154741 Prince JE, Cho JH, Dumontier E, Andrews W, Cutforth T, Tessier-Lavigne M, Parnavelas J, Cloutier JF, Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb. J Neurosci. 2009 Nov 11;29(45):14211-22
2	J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22
4*	J:309563 Rafipay A, Dun XP, Parkinson DB, Erskine L, Vargesson N, Knockdown of slit signaling during limb development leads to a reduction in humerus length. Dev Dyn. 2021 Sep;250(9):1340-1357
1	J:298694 Rattner A, Terrillion CE, Jou C, Kleven T, Hu SF, Williams J, Hou Z, Aggarwal M, Mori S, Shin G, Goff LA, Witter MP, Pletnikov M, Fenton AA, Nathans J, Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus. Elife. 2020 Oct 21;9:e62766
1	J:247474 Renier N, Dominici C, Erzurumlu RS, Kratochwil CF, Rijli FM, Gaspar P, Chedotal A, A mutant with bilateral whisker to barrel inputs unveils somatosensory mapping rules in the cerebral cortex. Elife. 2017 Mar 28;6:e23494
11	J:158918 Renier N, Schonewille M, Giraudet F, Badura A, Tessier-Lavigne M, Avan P, De Zeeuw CI, Chedotal A, Genetic dissection of the function of hindbrain axonal commissures. PLoS Biol. 2010;8(3):e1000325
2	J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425
1	J:174965 Ruiz de Almodovar C, Fabre PJ, Knevels E, Coulon C, Segura I, Haddick PC, Aerts L, Delattin N, Strasser G, Oh WJ, Lange C, Vinckier S, Haigh J, Fouquet C, Gu C, Alitalo K, Castellani V, Tessier-Lavigne M, Chedotal A, Charron F, Carmeliet P, VEGF mediates commissural axon chemoattraction through its receptor Flk1. Neuron. 2011 Jun 9;70(5):966-78
4	J:89438 Sabatier C, Plump AS, Le Ma, Brose K, Tamada A, Murakami F, Lee EY, Tessier-Lavigne M, The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons. Cell. 2004 Apr 16;117(2):157-69
2	J:335681 Schlienger S, Yam PT, Balekoglu N, Ducuing H, Michaud JF, Makihara S, Kramer DK, Chen B, Fasano A, Berardelli A, Hamdan FF, Rouleau GA, Srour M, Charron F, Genetics of mirror movements identifies a multifunctional complex required for Netrin-1 guidance and lateralization of motor control. Sci Adv. 2023 May 12;9(19):eadd5501
2	J:215618 Schmidt ER, Brignani S, Adolfs Y, Lemstra S, Demmers J, Vidaki M, Donahoo AL, Lillevali K, Vasar E, Richards LJ, Karagogeos D, Kolk SM, Pasterkamp RJ, Subdomain-mediated axon-axon signaling and chemoattraction cooperate to regulate afferent innervation of the lateral habenula. Neuron. 2014 Jul 16;83(2):372-87
4*	J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
3	J:304680 Skarlatou S, Herent C, Toscano E, Mendes CS, Bouvier J, Zampieri N, Afadin Signaling at the Spinal Neuroepithelium Regulates Central Canal Formation and Gait Selection. Cell Rep. 2020 Jun 9;31(10):107741
1	J:96006 Steele-Perkins G, Plachez C, Butz KG, Yang G, Bachurski CJ, Kinsman SL, Litwack ED, Richards LJ, Gronostajski RM, The transcription factor gene Nfib is essential for both lung maturation and brain development. Mol Cell Biol. 2005 Jan;25(2):685-98
2	J:143208 Tamada A, Kumada T, Zhu Y, Matsumoto T, Hatanaka Y, Muguruma K, Chen Z, Tanabe Y, Torigoe M, Yamauchi K, Oyama H, Nishida K, Murakami F, Crucial roles of Robo proteins in midline crossing of cerebellofugal axons and lack of their up-regulation after midline crossing. Neural Dev. 2008;3:29
1	J:301210 Taroc EZM, Katreddi RR, Forni PE, Identifying Isl1 Genetic Lineage in the Developing Olfactory System and in GnRH-1 Neurons. Front Physiol. 2020;11:601923
1*	J:276901 Taroc EZM, Lin JM, Tulloch AJ, Jaworski A, Forni PE, GnRH-1 Neural Migration From the Nose to the Brain Is Independent From Slit2, Robo3 and NELL2 Signaling. Front Cell Neurosci. 2019;13:70
2	J:245068 Taroc EZM, Prasad A, Lin JM, Forni PE, The terminal nerve plays a prominent role in GnRH-1 neuronal migration independent from proper olfactory and vomeronasal connections to the olfactory bulbs. Biol Open. 2017 Oct 15;6(10):1552-1568
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:154456 Thompson H, Andrews W, Parnavelas JG, Erskine L, Robo2 is required for Slit-mediated intraretinal axon guidance. Dev Biol. 2009 Nov 15;335(2):418-26
3	J:214891 Torigoe M, Yamauchi K, Tamada A, Matsuda I, Aiba A, Castellani V, Murakami F, Role of neuropilin-2 in the ipsilateral growth of midbrain dopaminergic axons. Eur J Neurosci. 2013 May;37(10):1573-83
3	J:282827 Tulloch AJ, Teo S, Carvajal BV, Tessier-Lavigne M, Jaworski A, Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3(Cre) mouse. J Comp Neurol. 2019 Dec 15;527(18):2948-2972
6	J:326542 van de Haar LL, Riga D, Boer JE, Garritsen O, Adolfs Y, Sieburgh TE, van Dijk RE, Watanabe K, van Kronenburg NCH, Broekhoven MH, Posthuma D, Meye FJ, Basak O, Pasterkamp RJ, Molecular signatures and cellular diversity during mouse habenula development. Cell Rep. 2022 Jul 5;40(1):111029
3*	J:248983 Varadarajan SG, Butler SJ, Netrin1 establishes multiple boundaries for axon growth in the developing spinal cord. Dev Biol. 2017 Oct 1;430(1):177-187
1	J:256148 Varadarajan SG, Kong JH, Phan KD, Kao TJ, Panaitof SC, Cardin J, Eltzschig H, Kania A, Novitch BG, Butler SJ, Netrin1 Produced by Neural Progenitors, Not Floor Plate Cells, Is Required for Axon Guidance in the Spinal Cord. Neuron. 2017 May 17;94(4):790-799.e3
3*	J:70834 Vargesson N, Luria V, Messina I, Erskine L, Laufer E, Expression patterns of Slit and Robo family members during vertebrate limb development. Mech Dev. 2001 Aug;106(1-2):175-80
2	J:272890 Wu Z, Makihara S, Yam PT, Teo S, Renier N, Balekoglu N, Moreno-Bravo JA, Olsen O, Chedotal A, Charron F, Tessier-Lavigne M, Long-Range Guidance of Spinal Commissural Axons by Netrin1 and Sonic Hedgehog from Midline Floor Plate Cells. Neuron. 2019 Feb 20;101(4):635-647.e4
1	J:308696 Wurmser M, Muppavarapu M, Tait CM, Laumonnerie C, Gonzalez-Castrillon LM, Wilson SI, Robo2 Receptor Gates the Anatomical Divergence of Neurons Derived From a Common Precursor Origin. Front Cell Dev Biol. 2021;9:668175
4*	J:138310 Xu C, Fan CM, Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei. Gene Expr Patterns. 2008 Sep;8(7-8):502-7
1	J:211644 Xu K, Wu Z, Renier N, Antipenko A, Tzvetkova-Robev D, Xu Y, Minchenko M, Nardi-Dei V, Rajashankar KR, Himanen J, Tessier-Lavigne M, Nikolov DB, Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism. Science. 2014 Jun 13;344(6189):1275-9
5	J:253878 Yamauchi K, Yamazaki M, Abe M, Sakimura K, Lickert H, Kawasaki T, Murakami F, Hirata T, Netrin-1 Derived from the Ventricular Zone, but not the Floor Plate, Directs Hindbrain Commissural Axons to the Ventral Midline. Sci Rep. 2017 Sep 20;7(1):11992
4	J:210623 Yeh ML, Gonda Y, Mommersteeg MT, Barber M, Ypsilanti AR, Hanashima C, Parnavelas JG, Andrews WD, Robo1 modulates proliferation and neurogenesis in the developing neocortex. J Neurosci. 2014 Apr 16;34(16):5717-31
10*	J:53337 Yuan SS, Cox LA, Dasika GK, Lee EY, Cloning and functional studies of a novel gene aberrantly expressed in RB-deficient embryos. Dev Biol. 1999 Mar 1;207(1):62-75
4*	J:78851 Yuan SS, Yeh YT, Lee EY, Pax-2 interacts with RB and reverses its repression on the promoter of Rig-1, a Robo member. Biochem Biophys Res Commun. 2002 Aug 30;296(4):1019-25
1	J:226697 Yung AR, Nishitani AM, Goodrich LV, Phenotypic analysis of mice completely lacking netrin 1. Development. 2015 Nov 1;142(21):3686-91
1*	J:332134 Zang Y, Chaudhari K, Bashaw GJ, Tace/ADAM17 is a bi-directional regulator of axon guidance that coordinates distinct Frazzled and Dcc receptor signaling outputs. Cell Rep. 2022 Dec 6;41(10):111785
1	J:218606 Zelina P, Blockus H, Zagar Y, Peres A, Friocourt F, Wu Z, Rama N, Fouquet C, Hohenester E, Tessier-Lavigne M, Schweitzer J, Roest Crollius H, Chedotal A, Signaling switch of the axon guidance receptor Robo3 during vertebrate evolution. Neuron. 2014 Dec 17;84(6):1258-72
1	J:294199 Zhu Y, Hirata T, Mackay F, Murakami F, Chemokine receptor CXCR7 non-cell-autonomously controls pontine neuronal migration and nucleus formation. Sci Rep. 2020 Jul 16;10(1):11830
4*	J:276416 Zhuang M, Li X, Zhu J, Zhang J, Niu F, Liang F, Chen M, Li D, Han P, Ji SJ, The m6A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expression. Nucleic Acids Res. 2019 May 21;47(9):4765-4777