Gene Expression Literature Summary

• Symbol: Spry4
• Name: sprouty RTK signaling antagonist 4
• ID: MGI:1345144

87 matching records from 87 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E2.5	E3	E3.5	E4	E4.5	E5	E5.5	E6	E6.5	E7	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14.5	E15.5	E16.5	E17.5	E18.5	E19.5	E	P
Immunohistochemistry (section)																											1
In situ RNA (section)												2	1	1	1		1		1		8		4	12	1	6	1	1		2	3
In situ RNA (whole mount)							2		2	1	3	3	4	1	9	2	16	2	6	2	5		2		1	1				2
In situ reporter (knock in)		1	1	1	1	1	1	1	1	1	2	2	1	1			1				1		1								1
Northern blot																														1	1
Western blot																					1		1	1		1				1
RT-PCR	1	1	1	1									3		2		1		6	2	5	1	3	3	1	1		2	1		3
cDNA clones																															1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Spry4  sprouty RTK signaling antagonist 4   (Synonyms: A030006O18Rik, sprouty4)
Results	Reference
2*	J:92174 Aberg T, Wang XP, Kim JH, Yamashiro T, Bei M, Rice R, Ryoo HM, Thesleff I, Runx2 mediates FGF signaling from epithelium to mesenchyme during tooth morphogenesis. Dev Biol. 2004 Jun 1;270(1):76-93
1	J:194074 Ahn Y, Sims C, Logue JM, Weatherbee SD, Krumlauf R, Lrp4 and Wise interplay controls the formation and patterning of mammary and other skin appendage placodes by modulating Wnt signaling. Development. 2013 Feb 1;140(3):583-93
3	J:326354 Allegre N, Chauveau S, Dennis C, Renaud Y, Meistermann D, Estrella LV, Pouchin P, Cohen-Tannoudji M, David L, Chazaud C, NANOG initiates epiblast fate through the coordination of pluripotency genes expression. Nat Commun. 2022 Jun 21;13(1):3550
1	J:313582 Anderson MJ, Magidson V, Kageyama R, Lewandoski M, Fgf4 maintains Hes7 levels critical for normal somite segmentation clock function. Elife. 2020 Nov 19;9:e55608
1	J:220460 Andre P, Song H, Kim W, Kispert A, Yang Y, Wnt5a and Wnt11 regulate mammalian anterior-posterior axis elongation. Development. 2015 Apr 15;142(8):1516-27
1	J:226487 Bagheri-Fam S, Ono M, Li L, Zhao L, Ryan J, Lai R, Katsura Y, Rossello FJ, Koopman P, Scherer G, Bartsch O, Eswarakumar JV, Harley VR, FGFR2 mutation in 46,XY sex reversal with craniosynostosis. Hum Mol Genet. 2015 Dec 1;24(23):6699-710
1*	J:245730 Bardot P, Vincent SD, Fournier M, Hubaud A, Joint M, Tora L, Pourquie O, The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo. Development. 2017 Oct 15;144(20):3808-3818
2	J:283343 Bastida MF, Perez-Gomez R, Trofka A, Zhu J, Rada-Iglesias A, Sheth R, Stadler HS, Mackem S, Ros MA, The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13. Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1090-1096
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1	J:289636 Berenguer M, Meyer KF, Yin J, Duester G, Discovery of genes required for body axis and limb formation by global identification of retinoic acid-regulated epigenetic marks. PLoS Biol. 2020 May;18(5):e3000719
1	J:293772 Bird AD, Croft BM, Harada M, Tang L, Zhao L, Ming Z, Bagheri-Fam S, Koopman P, Wang Z, Akita K, Harley VR, Ovotesticular disorders of sex development in FGF9 mouse models of human synostosis syndromes. Hum Mol Genet. 2020 Aug 3;29(13):2148-2161
2*	J:156788 Bouma GJ, Hudson QJ, Washburn LL, Eicher EM, New candidate genes identified for controlling mouse gonadal sex determination and the early stages of granulosa and Sertoli cell differentiation. Biol Reprod. 2010 Feb;82(2):380-9
1	J:158529 Burgess D, Zhang Y, Siefker E, Vaca R, Kuracha MR, Reneker L, Overbeek PA, Govindarajan V, Activated Ras alters lens and corneal development through induction of distinct downstream targets. BMC Dev Biol. 2010;10:13
1	J:153595 Butterfield NC, Metzis V, McGlinn E, Bruce SJ, Wainwright BJ, Wicking C, Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb. Development. 2009 Oct;136(20):3515-24
1	J:185530 Chan KM, Wong HL, Jin G, Liu B, Cao R, Cao Y, Lehti K, Tryggvason K, Zhou Z, MT1-MMP Inactivates ADAM9 to Regulate FGFR2 Signaling and Calvarial Osteogenesis. Dev Cell. 2012 Jun 12;22(6):1176-90
1	J:273652 Chao CM, Moiseenko A, Kosanovic D, Rivetti S, El Agha E, Wilhelm J, Kampschulte M, Yahya F, Ehrhardt H, Zimmer KP, Barreto G, Rizvanov AA, Schermuly RT, Reiss I, Morty RE, Rottier RJ, Bellusci S, Zhang JS, Impact of Fgf10 deficiency on pulmonary vasculature formation in a mouse model of bronchopulmonary dysplasia. Hum Mol Genet. 2019 May 1;28(9):1429-1444
1	J:241728 Chao CM, Yahya F, Moiseenko A, Tiozzo C, Shrestha A, Ahmadvand N, El Agha E, Quantius J, Dilai S, Kheirollahi V, Jones M, Wilhem J, Carraro G, Ehrhardt H, Zimmer KP, Barreto G, Ahlbrecht K, Morty RE, Herold S, Abellar RG, Seeger W, Schermuly R, Zhang JS, Minoo P, Bellusci S, Fgf10 deficiency is causative for lethality in a mouse model of bronchopulmonary dysplasia. J Pathol. 2017 Jan;241(1):91-103
2	J:176242 Charles C, Hovorakova M, Ahn Y, Lyons DB, Marangoni P, Churava S, Biehs B, Jheon A, Lesot H, Balooch G, Krumlauf R, Viriot L, Peterkova R, Klein OD, Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling. Development. 2011 Sep;138(18):4063-73
2	J:206582 Ching ST, Cunha GR, Baskin LS, Basson MA, Klein OD, Coordinated activity of Spry1 and Spry2 is required for normal development of the external genitalia. Dev Biol. 2014 Feb 1;386(1):1-11
1	J:131535 De Langhe SP, Carraro G, Tefft D, Li C, Xu X, Chai Y, Minoo P, Hajihosseini MK, Drouin J, Kaartinen V, Bellusci S, Formation and Differentiation of Multiple Mesenchymal Lineages during Lung Development Is Regulated by beta-catenin Signaling. PLoS One. 2008;3(1):e1516
1	J:114396 De Langhe SP, Carraro G, Warburton D, Hajihosseini MK, Bellusci S, Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung. Dev Biol. 2006 Nov 1;299(1):52-62
7*	J:54185 de Maximy AA, Nakatake Y, Moncada S, Itoh N, Thiery JP, Bellusci S, Cloning and expression pattern of a mouse homologue of drosophila sprouty in the mouse embryo. Mech Dev. 1999 Mar;81(1-2):213-6
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
2	J:218169 Donnison M, Broadhurst R, Pfeffer PL, Elf5 and Ets2 maintain the mouse extraembryonic ectoderm in a dosage dependent synergistic manner. Dev Biol. 2015 Jan 1;397(1):77-88
1	J:200023 Farin HF, Ludtke TH, Schmidt MK, Placzko S, Schuster-Gossler K, Petry M, Christoffels VM, Kispert A, Tbx2 terminates shh/fgf signaling in the developing mouse limb bud by direct repression of gremlin1. PLoS Genet. 2013;9(4):e1003467
1*	J:61523 Goldman DC, Martin GR, Tam PP, Fate and function of the ventral ectodermal ridge during mouse tail development. Development. 2000 May;127(10):2113-23
1	J:259795 Green RM, Fish JL, Young NM, Smith FJ, Roberts B, Dolan K, Choi I, Leach CL, Gordon P, Cheverud JM, Roseman CC, Williams TJ, Marcucio RS, Hallgrimsson B, Developmental nonlinearity drives phenotypic robustness. Nat Commun. 2017 Dec 6;8(1):1970
2	J:148879 Hayashi S, Shimoda T, Nakajima M, Tsukada Y, Sakumura Y, Dale JK, Maroto M, Kohno K, Matsui T, Bessho Y, Sprouty4, an FGF inhibitor, displays cyclic gene expression under the control of the notch segmentation clock in the mouse PSM. PLoS One. 2009;4(5):e5603
1	J:259186 Heng X, Guo Q, Leung AW, Li JY, Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6:e23253
1*	J:231083 Hines EA, Verheyden JM, Lashua AJ, Larson SC, Branchfield K, Domyan ET, Gao J, Harvey JF, Herriges JC, Hu L, Mcculley DJ, Throckmorton K, Yokoyama S, Ikeda A, Xu G, Sun X, Syndactyly in a novel Fras1(rdf) mutant results from interruption of signals for interdigital apoptosis. Dev Dyn. 2016 Apr;245(4):497-507
2	J:235521 Joo A, Long R, Cheng Z, Alexander C, Chang W, Klein OD, Sprouty2 regulates endochondral bone formation by modulation of RTK and BMP signaling. Bone. 2016 Jul;88:170-9
1	J:216160 Jurberg AD, Aires R, Novoa A, Rowland JE, Mallo M, Compartment-dependent activities of Wnt3a/beta-catenin signaling during vertebrate axial extension. Dev Biol. 2014 Oct 15;394(2):253-63
2	J:130572 Klein OD, Lyons DB, Balooch G, Marshall GW, Basson MA, Peterka M, Boran T, Peterkova R, Martin GR, An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors. Development. 2008 Jan;135(2):377-85
3	J:119280 Klein OD, Minowada G, Peterkova R, Kangas A, Yu BD, Lesot H, Peterka M, Jernvall J, Martin GR, Sprouty genes control diastema tooth development via bidirectional antagonism of epithelial-mesenchymal FGF signaling. Dev Cell. 2006 Aug;11(2):181-90
1*	J:238344 Koledova Z, Zhang X, Streuli C, Clarke RB, Klein OD, Werb Z, Lu P, SPRY1 regulates mammary epithelial morphogenesis by modulating EGFR-dependent stromal paracrine signaling and ECM remodeling. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):E5731-40
3	J:181400 Kuracha MR, Burgess D, Siefker E, Cooper JT, Licht JD, Robinson ML, Govindarajan V, Spry1 and Spry2 are necessary for lens vesicle separation and corneal differentiation. Invest Ophthalmol Vis Sci. 2011 Aug;52(9):6887-97
3*	J:203791 Kuracha MR, Siefker E, Licht JD, Govindarajan V, Spry1 and Spry2 are necessary for eyelid closure. Dev Biol. 2013 Nov 15;383(2):227-38
3	J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670
1	J:167213 Lagha M, Sato T, Regnault B, Cumano A, Zuniga A, Licht J, Relaix F, Buckingham M, Transcriptome analyses based on genetic screens for Pax3 myogenic targets in the mouse embryo. BMC Genomics. 2010;11:696
1	J:250062 Li A, Ma S, Smith SM, Lee MK, Fischer A, Borok Z, Bellusci S, Li C, Minoo P, Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate. BMC Biol. 2016 Mar 16;14:19
1	J:323097 Li-Villarreal N, Wong RLY, Garcia MD, Udan RS, Poche RA, Rasmussen TL, Rhyner AM, Wythe JD, Dickinson ME, FOXO1 represses sprouty 2 and sprouty 4 expression to promote arterial specification and vascular remodeling in the mouse yolk sac. Development. 2022 Apr 1;149(7):dev200131
1	J:97106 Lin W, Jing N, Basson MA, Dierich A, Licht J, Ang SL, Synergistic activity of Sef and Sprouty proteins in regulating the expression of Gbx2 in the mid-hindbrain region. Genesis. 2005 Mar;41(3):110-5
2	J:184012 Lopez-Rios J, Speziale D, Robay D, Scotti M, Osterwalder M, Nusspaumer G, Galli A, Hollander GA, Kmita M, Zeller R, GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis. Dev Cell. 2012 Apr 17;22(4):837-48
1	J:175781 Makki N, Capecchi MR, Identification of novel Hoxa1 downstream targets regulating hindbrain, neural crest and inner ear development. Dev Biol. 2011 Sep 15;357(2):295-304
7*	J:55241 Minowada G, Jarvis LA, Chi CL, Neubuser A, Sun X, Hacohen N, Krasnow MA, Martin GR, Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. Development. 1999 Oct;126(20):4465-75
2*	J:203635 Miraoui H, Dwyer AA, Sykiotis GP, Plummer L, Chung W, Feng B, Beenken A, Clarke J, Pers TH, Dworzynski P, Keefe K, Niedziela M, Raivio T, Crowley WF Jr, Seminara SB, Quinton R, Hughes VA, Kumanov P, Young J, Yialamas MA, Hall JE, Van Vliet G, Chanoine JP, Rubenstein J, Mohammadi M, Tsai PS, Sidis Y, Lage K, Pitteloud N, Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism. Am J Hum Genet. 2013 May 2;92(5):725-43
2	J:308524 Morgani SM, Hadjantonakis AK, Quantitative analysis of signaling responses during mouse primordial germ cell specification. Biol Open. 2021 May 15;10(5):bio058741
26*	J:264612 Morgani SM, Saiz N, Garg V, Raina D, Simon CS, Kang M, Arias AM, Nichols J, Schroter C, Hadjantonakis AK, A Sprouty4 reporter to monitor FGF/ERK signaling activity in ESCs and mice. Dev Biol. 2018 Sep 1;441(1):104-126
2	J:308051 Morgani SM, Su J, Nichols J, Massague J, Hadjantonakis AK, The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos. Elife. 2021 Apr 30;10:e64811
1*	J:192269 Mukhopadhyay A, Krishnaswami SR, Cowing-Zitron C, Hung NJ, Reilly-Rhoten H, Burns J, Yu BD, Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development. Dev Biol. 2013 Jan 15;373(2):373-82
2	J:170831 Naiche LA, Holder N, Lewandoski M, FGF4 and FGF8 comprise the wavefront activity that controls somitogenesis. Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4018-23
1	J:77442 Niederreither K, Vermot J, Schuhbaur B, Chambon P, Dolle P, Embryonic retinoic acid synthesis is required for forelimb growth and anteroposterior patterning in the mouse. Development. 2002 Aug;129(15):3563-74
1	J:124102 Niwa Y, Masamizu Y, Liu T, Nakayama R, Deng CX, Kageyama R, The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and notch signaling in the somite segmentation clock. Dev Cell. 2007 Aug;13(2):298-304
3	J:214075 Norrie JL, Lewandowski JP, Bouldin CM, Amarnath S, Li Q, Vokes MS, Ehrlich LI, Harfe BD, Vokes SA, Dynamics of BMP signaling in limb bud mesenchyme and polydactyly. Dev Biol. 2014 Sep 15;393(2):270-81
2	J:237505 Norrie JL, Li Q, Co S, Huang BL, Ding D, Uy JC, Ji Z, Mackem S, Bedford MT, Galli A, Ji H, Vokes SA, PRMT5 is essential for the maintenance of chondrogenic progenitor cells in the limb bud. Development. 2016 Dec 15;143(24):4608-4619
2	J:173447 Petersen CI, Jheon AH, Mostowfi P, Charles C, Ching S, Thirumangalathu S, Barlow LA, Klein OD, FGF Signaling Regulates the Number of Posterior Taste Papillae by Controlling Progenitor Field Size. PLoS Genet. 2011 Jun;7(6):e1002098
2*	J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8
2	J:171448 Probst S, Kraemer C, Demougin P, Sheth R, Martin GR, Shiratori H, Hamada H, Iber D, Zeller R, Zuniga A, SHH propagates distal limb bud development by enhancing CYP26B1-mediated retinoic acid clearance via AER-FGF signalling. Development. 2011 May;138(10):1913-23
1	J:356701 Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD, Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr;91(4):387-93
2*	J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188
1*	J:277331 Sah RK, Yang A, Bah FB, Adlat S, Bohio AA, Oo ZM, Wang C, Myint MZZ, Bahadar N, Zhang L, Feng X, Zheng Y, Transcriptome profiling of mouse brain and lung under Dip2a regulation using RNA-sequencing. PLoS One. 2019;14(7):e0213702
3	J:158139 Seifert AW, Yamaguchi T, Cohn MJ, Functional and phylogenetic analysis shows that Fgf8 is a marker of genital induction in mammals but is not required for external genital development. Development. 2009 Aug;136(15):2643-51
2	J:119477 Shaw AT, Meissner A, Dowdle JA, Crowley D, Magendantz M, Ouyang C, Parisi T, Rajagopal J, Blank LJ, Bronson RT, Stone JR, Tuveson DA, Jaenisch R, Jacks T, Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis. Genes Dev. 2007 Mar 15;21(6):694-707
1	J:235717 Shi H, O'Reilly VC, Moreau JL, Bewes TR, Yam MX, Chapman BE, Grieve SM, Stocker R, Graham RM, Chapman G, Sparrow DB, Dunwoodie SL, Gestational stress induces the unfolded protein response, resulting in heart defects. Development. 2016 Jul 15;143(14):2561-72
2	J:176064 Shimokawa K, Kimura-Yoshida C, Nagai N, Mukai K, Matsubara K, Watanabe H, Matsuda Y, Mochida K, Matsuo I, Cell surface heparan sulfate chains regulate local reception of FGF signaling in the mouse embryo. Dev Cell. 2011 Aug 16;21(2):257-72
1*	J:185606 Simrick S, Szumska D, Gardiner JR, Jones K, Sagar K, Morrow B, Bhattacharya S, Basson MA, Biallelic expression of Tbx1 protects the embryo from developmental defects caused by increased receptor tyrosine kinase signaling. Dev Dyn. 2012 Aug;241(8):1310-24
1	J:186213 Sparrow DB, Chapman G, Smith AJ, Mattar MZ, Major JA, O'Reilly VC, Saga Y, Zackai EH, Dormans JP, Alman BA, McGregor L, Kageyama R, Kusumi K, Dunwoodie SL, A mechanism for gene-environment interaction in the etiology of congenital scoliosis. Cell. 2012 Apr 13;149(2):295-306
1	J:78402 Sun X, Mariani FV, Martin GR, Functions of FGF signalling from the apical ectodermal ridge in limb development. Nature. 2002 Aug 1;418(6897):501-8
5*	J:168653 Sylvestersen KB, Herrera PL, Serup P, Rescan C, Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):105-11
1	J:157263 Talamillo A, Delgado I, Nakamura T, de-Vega S, Yoshitomi Y, Unda F, Birchmeier W, Yamada Y, Ros MA, Role of Epiprofin, a zinc-finger transcription factor, in limb development. Dev Biol. 2010 Jan 15;337(2):363-74
2	J:119645 Thomson RE, Pellicano F, Iwata T, Fibroblast growth factor receptor 3 kinase domain mutation increases cortical progenitor proliferation via mitogen-activated protein kinase activation. J Neurochem. 2007 Mar;100(6):1565-78
2	J:105216 Trokovic N, Trokovic R, Partanen J, Fibroblast growth factor signalling and regional specification of the pharyngeal ectoderm. Int J Dev Biol. 2005;49(7):797-805
1	J:147278 Tzchori I, Day TF, Carolan PJ, Zhao Y, Wassif CA, Li L, Lewandoski M, Gorivodsky M, Love PE, Porter FD, Westphal H, Yang Y, LIM homeobox transcription factors integrate signaling events that control three-dimensional limb patterning and growth. Development. 2009 Apr;136(8):1375-85
1	J:185604 van Rooijen C, Simmini S, Bialecka M, Neijts R, van de Ven C, Beck F, Deschamps J, Evolutionarily conserved requirement of Cdx for post-occipital tissue emergence. Development. 2012 Jul;139(14):2576-83
2	J:101736 Verheyden JM, Lewandoski M, Deng C, Harfe BD, Sun X, Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning. Development. 2005 Oct;132(19):4235-45
4	J:138578 Verheyden JM, Sun X, An Fgf/Gremlin inhibitory feedback loop triggers termination of limb bud outgrowth. Nature. 2008 Jul 31;454(7204):638-41
1*	J:166923 Wang B, Sinha T, Jiao K, Serra R, Wang J, Disruption of PCP signaling causes limb morphogenesis and skeletal defects and may underlie Robinow syndrome and brachydactyly type B. Hum Mol Genet. 2011 Jan 15;20(2):271-85
1	J:238549 Warrier S, Nuwayhid S, Sabatino JA, Sugrue KF, Zohn IE, Supt20 is required for development of the axial skeleton. Dev Biol. 2017 Jan 15;421(2):245-257
1*	J:108519 Waters ST, Lewandoski M, A threshold requirement for Gbx2 levels in hindbrain development. Development. 2006 May;133(10):1991-2000
1	J:347414 Yang J, Zhu L, Pan H, Ueharu H, Toda M, Yang Q, Hallett SA, Olson LE, Mishina Y, A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis. J Clin Invest. 2024 Mar 11;134(8)
1	J:296446 Yang LM, Stout L, Rauchman M, Ornitz DM, Analysis of FGF20-regulated genes in organ of Corti progenitors by translating ribosome affinity purification. Dev Dyn. 2020 Oct;249(10):1217-1242
4	J:138616 Yang X, Harkins LK, Zubanova O, Harrington A, Kovalenko D, Nadeau RJ, Chen PY, Toher JL, Lindner V, Liaw L, Friesel R, Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia. Dev Biol. 2008 Sep 1;321(1):64-76
1	J:142646 Yi L, Domyan ET, Lewandoski M, Sun X, Fibroblast growth factor 9 signaling inhibits airway smooth muscle differentiation in mouse lung. Dev Dyn. 2008 Dec 18;238(1):123-137
3	J:173529 Yu T, Yaguchi Y, Echevarria D, Martinez S, Basson MA, Sprouty genes prevent excessive FGF signalling in multiple cell types throughout development of the cerebellum. Development. 2011 Jul;138(14):2957-68
1	J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510
2*	J:73297 Zhang S, Lin Y, Itaranta P, Yagi A, Vainio S, Expression of Sprouty genes 1, 2 and 4 during mouse organogenesis. Mech Dev. 2001 Dec;109(2):367-70
1	J:165810 Zhang Z, Sui P, Dong A, Hassell J, Cserjesi P, Chen YT, Behringer RR, Sun X, Preaxial polydactyly: interactions among ETV, TWIST1 and HAND2 control anterior-posterior patterning of the limb. Development. 2010 Oct;137(20):3417-26