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Gene Expression Literature Summary
Symbol
Name
ID
Nlrp5
NLR family, pyrin domain containing 5
MGI:1345193

24 matching records from 24 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E1.5 E2 E2.5 E3 E3.5 E4 E12.5 E14 E14.5 E16.5 E17.5 E18.5 P
Immunohistochemistry (section) 2 2 1 2 1 1 1 1 1 1 1 7
In situ RNA (section) 3
Immunohistochemistry (whole mount) 1 1 1 1 1 5
Northern blot 1 1 1 1 1 1 2
Western blot 1 1 1 1 1 2 11
RT-PCR 5 5 1 2 4 4 2 2 1 1 2 12
cDNA clones 1
RNase protection 1 1 1 1 2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Nlrp5  NLR family, pyrin domain containing 5   (Synonyms: Mater, Nalp5, Op1)
Results  Reference
6*J:112946 Evsikov AV, Graber JH, Brockman JM, Hampl A, Holbrook AE, Singh P, Eppig JJ, Solter D, Knowles BB, Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Genes Dev. 2006 Oct 1;20(19):2713-27
7J:116786 Falco G, Stanghellini I, Ko MS, Use of Chuk as an internal standard suitable for quantitative RT-PCR in mouse preimplantation embryos. Reprod Biomed Online. 2006 Sep;13(3):394-403
2J:296111 Gao Z, Zhang X, Yu X, Qin D, Xiao Y, Yu Y, Xiang Y, Nie X, Lu X, Liu W, Yi Z, Li L, Zbed3 participates in the subcortical maternal complex and regulates the distribution of organelles. J Mol Cell Biol. 2018 Feb 1;10(1):74-88
7J:93248 Hamatani T, Falco G, Carter MG, Akutsu H, Stagg CA, Sharov AA, Dudekula DB, VanBuren V, Ko MS, Age-associated alteration of gene expression patterns in mouse oocytes. Hum Mol Genet. 2004 Nov 1;13(19):2263-78
2J:355487 Han Z, Wang R, Chi P, Zhang Z, Min L, Jiao H, Ou G, Zhou D, Qin D, Xu C, Gao Z, Qi Q, Li J, Lu Y, Wang X, Chen J, Yu X, Hu H, Li L, Deng D, The subcortical maternal complex modulates the cell cycle during early mammalian embryogenesis via 14-3-3. Nat Commun. 2024 Oct 15;15(1):8887
2J:307968 He Y, Chen Q, Dai J, Cui Y, Zhang C, Wen X, Li J, Xiao Y, Peng X, Liu M, Shen B, Sha J, Hu Z, Li J, Shu W, Single-cell RNA-Seq reveals a highly coordinated transcriptional program in mouse germ cells during primordial follicle formation. Aging Cell. 2021 Jul;20(7):e13424
1J:282329 Hildebrandt MR, Wang Y, Li L, Yasmin L, Glubrecht DD, Godbout R, Cytoplasmic aggregation of DDX1 in developing embryos: Early embryonic lethality associated with Ddx1 knockout. Dev Biol. 2019 Nov 15;455(2):420-433
2*J:306241 Horikawa M, Kirkman NJ, Mayo KE, Mulders SM, Zhou J, Bondy CA, Hsu SY, King GJ, Adashi EY, The mouse germ-cell-specific leucine-rich repeat protein NALP14: a member of the NACHT nucleoside triphosphatase family. Biol Reprod. 2005 Apr;72(4):879-89
4*J:125833 Joshi S, Davies H, Sims LP, Levy SE, Dean J, Ovarian gene expression in the absence of FIGLA, an oocyte-specific transcription factor. BMC Dev Biol. 2007;7:67
4*J:165134 Kim B, Kan R, Anguish L, Nelson LM, Coonrod SA, Potential role for MATER in cytoplasmic lattice formation in murine oocytes. PLoS One. 2010;5(9):e12587
15*J:140105 Li L, Baibakov B, Dean J, A subcortical maternal complex essential for preimplantation mouse embryogenesis. Dev Cell. 2008 Sep;15(3):416-25
6J:270950 Lin K, Zhang S, Shi Q, Zhu M, Gao L, Xia W, Geng B, Zheng Z, Xu EY, Essential requirement of mammalian Pumilio family in embryonic development. Mol Biol Cell. 2018 Nov 26;29(24):2922-2932
2J:221014 Madissoon E, Tohonen V, Vesterlund L, Katayama S, Unneberg P, Inzunza J, Hovatta O, Kere J, Differences in gene expression between mouse and human for dynamically regulated genes in early embryo. PLoS One. 2014;9(8):e102949
1J:341543 Meng TG, Guo JN, Zhu L, Yin Y, Wang F, Han ZM, Lei L, Ma XS, Xue Y, Yue W, Nie XQ, Zhao ZH, Zhang HY, Sun SM, Ouyang YC, Hou Y, Schatten H, Ju Z, Ou XH, Wang ZB, Wong CCL, Li Z, Sun QY, NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte-to-Embryo Transition. Adv Sci (Weinh). 2023 Sep;10(27):e2301940
4J:326570 Niu W, Spradling AC, Mouse oocytes develop in cysts with the help of nurse cells. Cell. 2022 Jul 7;185(14):2576-2590.e12
15*J:130427 Ohsugi M, Zheng P, Baibakov B, Li L, Dean J, Maternally derived FILIA-MATER complex localizes asymmetrically in cleavage-stage mouse embryos. Development. 2008 Jan;135(2):259-69
3*J:284116 Qin D, Gao Z, Xiao Y, Zhang X, Ma H, Yu X, Nie X, Fan N, Wang X, Ouyang Y, Sun QY, Yi Z, Li L, The subcortical maternal complex protein Nlrp4f is involved in cytoplasmic lattice formation and organelle distribution. Development. 2019 Oct 18;146(20):dev183616
1J:92421 Rajkovic A, Pangas SA, Ballow D, Suzumori N, Matzuk MM, NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression. Science. 2004 Aug 20;305(5687):1157-9
10J:88687 Tong ZB, Gold L, De Pol A, Vanevski K, Dorward H, Sena P, Palumbo C, Bondy CA, Nelson LM, Developmental expression and subcellular localization of mouse MATER, an oocyte-specific protein essential for early development. Endocrinology. 2004 Mar;145(3):1427-34
7J:56809 Tong ZB, Nelson LM, A mouse gene encoding an oocyte antigen associated with autoimmune premature ovarian failure [see comments]. Endocrinology. 1999 Aug;140(8):3720-6
1J:353355 Yao X, Wang C, Yu W, Sun L, Lv Z, Xie X, Tian S, Yan L, Li L, Liu J, BCAS2 regulates oocyte meiotic prophase I by participating in mRNA alternative splicing. FASEB J. 2024 Jan;38(1):e23361
3J:276268 Yu XJ, Yi Z, Gao Z, Qin D, Zhai Y, Chen X, Ou-Yang Y, Wang ZB, Zheng P, Zhu MS, Wang H, Sun QY, Dean J, Li L, The subcortical maternal complex controls symmetric division of mouse zygotes by regulating F-actin dynamics. Nat Commun. 2014 Sep 11;5:4887
1J:344223 Zhang W, Zhang R, Wu L, Zhu C, Zhang C, Xu C, Zhao S, Liu X, Guo T, Lu Y, Gao Z, Yu X, Li L, Chen ZJ, Qin Y, Jiao X, NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance. Cell Rep. 2023 Dec 26;42(12):113531
2J:148330 Zheng P, Dean J, Role of Filia, a maternal effect gene, in maintaining euploidy during cleavage-stage mouse embryogenesis. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7473-8

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory