Gene Expression Literature Summary

• Symbol: Map2k3
• Name: mitogen-activated protein kinase kinase 3
• ID: MGI:1346868

8 matching records from 8 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E2.5	E3	E4	E9	E9.5	E11.5	E13.5	E14.5	E15.5	E16.5	E18.5	P
Immunohistochemistry (section)							1	1
In situ RNA (section)											1
Immunohistochemistry (whole mount)	1	1	1	1	1	1
In situ RNA (whole mount)									1			1
Western blot							1
RT-PCR	1	1	1	1	1	1			1	1			1	1	2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Map2k3  mitogen-activated protein kinase kinase 3   (Synonyms: MAP kinase kinase 3, MKK3, Prkmk3)
Results	Reference
1	J:101350 Abell AN, Rivera-Perez JA, Cuevas BD, Uhlik MT, Sather S, Johnson NL, Minton SK, Lauder JM, Winter-Vann AM, Nakamura K, Magnuson T, Vaillancourt RR, Heasley LE, Johnson GL, Ablation of MEKK4 kinase activity causes neurulation and skeletal patterning defects in the mouse embryo. Mol Cell Biol. 2005 Oct;25(20):8948-59
2	J:206898 Banh S, Hales BF, Hydroxyurea exposure triggers tissue-specific activation of p38 mitogen-activated protein kinase signaling and the DNA damage response in organogenesis-stage mouse embryos. Toxicol Sci. 2013 Jun;133(2):298-308
1	J:141953 Derradji H, Bekaert S, De Meyer T, Jacquet P, Abou-El-Ardat K, Ghardi M, Arlette M, Baatout S, Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects. Dev Biol. 2008 Aug 7;322(2):302-313
13*	J:119912 Fong B, Watson PH, Watson AJ, Mouse preimplantation embryo responses to culture medium osmolarity include increased expression of CCM2 and p38 MAPK activation. BMC Dev Biol. 2007;7:2
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
3	J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
2	J:236335 Warr N, Siggers P, Carre GA, Wells S, Greenfield A, Genetic Analyses Reveal Functions for MAP2K3 and MAP2K6 in Mouse Testis Determination. Biol Reprod. 2016 May;94(5):103