Gene Expression Literature Summary

• Symbol: Slc27a4
• Name: solute carrier family 27 (fatty acid transporter), member 4
• ID: MGI:1347347

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7.5	E8	E8.5	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16	E16.5	E17.5	E18	E18.5	E19	E	P
Immunohistochemistry (section)			1			1			1					1		2			6
In situ RNA (section)	1	2		1				1	1	1	1		1	1		1			3
Northern blot																			1
Western blot					1	1	1		1					1					4
RT-PCR		1		1	1	2	1	1	1		1	1		2	1	3	1	2	9
cDNA clones						1													1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Slc27a4  solute carrier family 27 (fatty acid transporter), member 4   (Synonyms: FATP4, fatty acid transport protein 4)
Results	Reference
1	J:201436 Chang I, Bramall AN, Baynash AG, Rattner A, Rakheja D, Post M, Joza S, McKerlie C, Stewart DJ, McInnes RR, Yanagisawa M, Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice. J Clin Invest. 2013 Jun 3;123(6):2643-53
1	J:349093 Dearden L, Furigo IC, Pantaleao LC, Wong LWP, Fernandez-Twinn DS, de Almeida-Faria J, Kentistou KA, Carreira MV, Bidault G, Vidal-Puig A, Ong KK, Perry JRB, Donato J Jr, Ozanne SE, Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food. PLoS Biol. 2024 Jun;22(6):e3002641
2	J:86762 Gimeno RE, Hirsch DJ, Punreddy S, Sun Y, Ortegon AM, Wu H, Daniels T, Stricker-Krongrad A, Lodish HF, Stahl A, Targeted deletion of fatty acid transport protein-4 results in early embryonic lethality. J Biol Chem. 2003 Dec 5;278(49):49512-6
2	J:316550 Himes KP, Young A, Koppes E, Stolz D, Barak Y, Sadovsky Y, Chaillet JR, Loss of inherited genomic imprints in mice leads to severe disruption in placental lipid metabolism. Placenta. 2015 Apr;36(4):389-96
3*	J:42634 Hirsch D, Stahl A, Lodish HF, A family of fatty acid transporters conserved from mycobacterium to man. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8625-9
3	J:317603 Islam A, Kagawa Y, Sharifi K, Ebrahimi M, Miyazaki H, Yasumoto Y, Kawamura S, Yamamoto Y, Sakaguti S, Sawada T, Tokuda N, Sugino N, Suzuki R, Owada Y, Fatty Acid Binding Protein 3 Is Involved in n-3 and n-6 PUFA transport in mouse trophoblasts. J Nutr. 2014 Oct;144(10):1509-16
5	J:324027 Kappen C, Kruger C, Jones S, Salbaum JM, Nutrient Transporter Gene Expression in the Early Conceptus-Implications From Two Mouse Models of Diabetic Pregnancy. Front Cell Dev Biol. 2022;10:777844
1	J:317805 Kato A, Ito M, Sanaki T, Okuda T, Tsuchiya N, Yoshimoto R, Yukioka H, Acsl1 is essential for skin barrier function through the activation of linoleic acid and biosynthesis of omega-O-acylceramide in mice. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Feb;1867(2):159085
13	J:323371 Lee JG, Kim G, Park SG, Yon JM, Yeom J, Song HE, Cheong SA, Lim JS, Sung YH, Kim K, Yoo HJ, Hong EJ, Nam KH, Seong JK, Kim CJ, Nam SY, Baek IJ, Lipid signatures reflect the function of the murine primary placentation. Biol Reprod. 2022 Mar 19;106(3):583-596
5*	J:244468 Lin MH, Hsu FF, Miner JH, Requirement of fatty acid transport protein 4 for development, maturation, and function of sebaceous glands in a mouse model of ichthyosis prematurity syndrome. J Biol Chem. 2013 Feb 08;288(6):3964-76
4	J:307827 Lindegaard ML, Nielsen LB, Maternal diabetes causes coordinated down-regulation of genes involved with lipid metabolism in the murine fetal heart. Metabolism. 2008 Jun;57(6):766-73
1*	J:193822 Lumayag S, Haldin CE, Corbett NJ, Wahlin KJ, Cowan C, Turturro S, Larsen PE, Kovacs B, Witmer PD, Valle D, Zack DJ, Nicholson DA, Xu S, Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
10	J:178094 Mishima T, Miner JH, Morizane M, Stahl A, Sadovsky Y, The expression and function of fatty acid transport protein-2 and -4 in the murine placenta. PLoS One. 2011;6(10):e25865
3	J:122660 Moulson CL, Lin MH, White JM, Newberry EP, Davidson NO, Miner JH, Keratinocyte-specific expression of fatty acid transport protein 4 rescues the wrinkle-free phenotype in Slc27a4/Fatp4 mutant mice. J Biol Chem. 2007 May 25;282(21):15912-20
1*	J:242353 Pichery M, Huchenq A, Sandhoff R, Severino-Freire M, Zaafouri S, Opalka L, Levade T, Soldan V, Bertrand-Michel J, Lhuillier E, Serre G, Maruani A, Mazereeuw-Hautier J, Jonca N, PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier. Hum Mol Genet. 2017 May 15;26(10):1787-1800
2	J:129630 Schaiff WT, Knapp FF Jr, Barak Y, Biron-Shental T, Nelson DM, Sadovsky Y, Ligand-activated peroxisome proliferator activated receptor gamma alters placental morphology and placental fatty acid uptake in mice. Endocrinology. 2007 Aug;148(8):3625-34
3	J:103199 Schmuth M, Ortegon AM, Mao-Qiang M, Elias PM, Feingold KR, Stahl A, Differential expression of Fatty Acid transport proteins in epidermis and skin appendages. J Invest Dermatol. 2005 Dec;125(6):1174-81
4	J:57759 Stahl A, Hirsch DJ, Gimeno RE, Punreddy S, Ge P, Watson N, Patel S, Kotler M, Raimondi A, Tartaglia LA, Lodish HF, Identification of the major intestinal fatty acid transport protein. Mol Cell. 1999 Sep;4(3):299-308
1	J:194779 Tao J, Koster MI, Harrison W, Moran JL, Beier DR, Roop DR, Overbeek PA, A spontaneous Fatp4/Scl27a4 splice site mutation in a new murine model for congenital ichthyosis. PLoS One. 2012;7(11):e50634
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6