Gene Expression Literature Summary

• Symbol: Foxl1
• Name: forkhead box L1
• ID: MGI:1347469

25 matching records from 25 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E8.5	E9.5	E10	E10.5	E11	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E17.5	E18	E18.5	P
Immunohistochemistry (section)							1	1		1						2
In situ RNA (section)	1		2	1		1	1	3	2	5	1				1	4
Immunohistochemistry (whole mount)																1
In situ RNA (whole mount)		1			1						3
RT-PCR		1			1			2	1		1	1		1	2	1
cDNA clones		1
RNase protection			1		2		2	2	1	2	1	2	1		2	3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Foxl1  forkhead box L1   (Synonyms: fkh-6, fkh6, Fkh6, FREAC7)
Results	Reference
2	J:244068 Bohnenpoll T, Wittern AB, Mamo TM, Weiss AC, Rudat C, Kleppa MJ, Schuster-Gossler K, Wojahn I, Ludtke TH, Trowe MO, Kispert A, A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development. PLoS Genet. 2017 Aug;13(8):e1006951
3	J:311497 Everson JL, Fink DM, Yoon JW, Leslie EJ, Kietzman HW, Ansen-Wilson LJ, Chung HM, Walterhouse DO, Marazita ML, Lipinski RJ, Sonic hedgehog regulation of Foxf2 promotes cranial neural crest mesenchyme proliferation and is disrupted in cleft lip morphogenesis. Development. 2017 Jun 1;144(11):2082-2091
1	J:82631 Fukuda K, Yoshida H, Sato T, Furumoto TA, Mizutani-Koseki Y, Suzuki Y, Saito Y, Takemori T, Kimura M, Sato H, Taniguchi M, Nishikawa S, Nakayama T, Koseki H, Mesenchymal expression of Foxl1, a winged helix transcriptional factor, regulates generation and maintenance of gut-associated lymphoid organs. Dev Biol. 2003 Mar 15;255(2):278-89
1*	J:124920 Garrison WD, Battle MA, Yang C, Kaestner KH, Sladek FM, Duncan SA, Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon. Gastroenterology. 2006 Apr;130(4):1207-20
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1	J:191565 Grote P, Wittler L, Hendrix D, Koch F, Wahrisch S, Beisaw A, Macura K, Blass G, Kellis M, Werber M, Herrmann BG, The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse. Dev Cell. 2013 Jan 28;24(2):206-14
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2	J:249431 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ, Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 2017 Oct 10;6:e26851
1	J:59312 Jensen J, Pedersen EE, Galante P, Hald J, Heller RS, Ishibashi M, Kageyama R, Guillemot F, Serup P, Madsen OD, Control of endodermal endocrine development by Hes-1. Nat Genet. 2000 Jan;24(1):36-44
15*	J:33548 Kaestner KH, Bleckmann SC, Monaghan AP, Schlondorff J, Mincheva A, Lichter P, Schutz G, Clustered arrangement of winged helix genes fkh-6 and MFH-1: possible implications for mesoderm development. Development. 1996 Jun;122(6):1751-8
8*	J:14165 Kaestner KH, Lee KH, Schlondorff J, Hiemisch H, Monaghan AP, Schutz G, Six members of the mouse forkhead gene family are developmentally regulated. Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7628-31
2	J:41235 Kaestner KH, Silberg DG, Traber PG, Schutz G, The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation. Genes Dev. 1997 Jun 15;11(12):1583-95
6	J:308823 Kondo A, Kaestner KH, FoxL1(+) mesenchymal cells are a critical source of Wnt5a for midgut elongation during mouse embryonic intestinal development. Cells Dev. 2021 Mar;165:203662
1	J:190291 Madison BB, McKenna LB, Dolson D, Epstein DJ, Kaestner KH, FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine. J Biol Chem. 2009 Feb 27;284(9):5936-44
2	J:254493 Munoz-Bravo JL, Flores-Martinez A, Herrero-Martin G, Puri S, Taketo MM, Rojas A, Hebrok M, Cano DA, Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity. PLoS One. 2016;11(10):e0164714
2	J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7
1	J:194385 Steffes G, Lorente-Canovas B, Pearson S, Brooker RH, Spiden S, Kiernan AE, Guenet JL, Steel KP, Mutanlallemand (mtl) and Belly Spot and Deafness (bsd) are two new mutations of Lmx1a causing severe cochlear and vestibular defects. PLoS One. 2012;7(11):e51065
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1	J:64018 Wang CC, Biben C, Robb L, Nassir F, Barnett L, Davidson NO, Koentgen F, Tarlinton D, Harvey RP, Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera. Dev Biol. 2000 Aug 15;224(2):152-67
1	J:84053 Wang T, Tamakoshi T, Uezato T, Shu F, Kanzaki-Kato N, Fu Y, Koseki H, Yoshida N, Sugiyama T, Miura N, Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate. Dev Biol. 2003 Jul 1;259(1):83-94
1*	J:279388 Weiss AC, Bohnenpoll T, Kurz J, Blank P, Airik R, Ludtke TH, Kleppa MJ, Deuper L, Kaiser M, Mamo TM, Costa R, von Hahn T, Trowe MO, Kispert A, Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme. J Pathol. 2019 Aug;248(4):452-463
1*	J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
1	J:312414 Yogosawa S, Ohkido M, Horii T, Okazaki Y, Nakayama J, Yoshida S, Toyokuni S, Hatada I, Morimoto M, Yoshida K, Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient. Commun Biol. 2021 Oct 20;4(1):1204
1	J:352471 Yoshida S, Tsuneoka Y, Tsukada T, Nakakura T, Kawamura A, Kai W, Yoshida K, Primary Cilia are Required for Cell-Type Determination and Angiogenesis in Pituitary Development. Endocrinology. 2024 Jul 1;165(8)