Gene Expression Literature Summary

• Symbol: Aifm1
• Name: apoptosis-inducing factor, mitochondrion-associated 1
• ID: MGI:1349419

16 matching records from 16 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E1.5	E2	E7.5	E9.5	E10.5	E12.5	E13	E13.5	E14.5	E15.5	E17.5	E18.5	P
Immunohistochemistry (section)						2	1	2		2			2
In situ RNA (section)									1
Immunohistochemistry (whole mount)													1
Western blot			1	1	1	1				1			4
RT-PCR	1	1				1			1		1	1	2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Aifm1  apoptosis-inducing factor, mitochondrion-associated 1   (Synonyms: AIF, AIFsh2, apoptosis-inducing factor, Pdcd8)
Results	Reference
1	J:196570 Bae KB, Kim MO, Yu DH, Shin MJ, Kim HJ, Yuh HS, Ji YR, Kim JY, Kim JM, Hyun BH, Lee HC, Chang WK, Park SB, Kim do H, Lee HS, Choo YS, Lee S, Ryoo ZY, Overexpression of Jazf1 induces cardiac malformation through the upregulation of pro-apoptotic genes in mice. Transgenic Res. 2011 Oct;20(5):1019-31
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1*	J:111066 Brown D, Yu BD, Joza N, Benit P, Meneses J, Firpo M, Rustin P, Penninger JM, Martin GR, Loss of Aif function causes cell death in the mouse embryo, but the temporal progression of patterning is normal. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9918-23
1	J:306165 Delavallee L, Mathiah N, Cabon L, Mazeraud A, Brunelle-Navas MN, Lerner LK, Tannoury M, Prola A, Moreno-Loshuertos R, Baritaud M, Vela L, Garbin K, Garnier D, Lemaire C, Langa-Vives F, Cohen-Salmon M, Fernandez-Silva P, Chretien F, Migeotte I, Susin SA, Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus. Mol Metab. 2020 Oct;40:101027
2*	J:256078 Hangen E, Feraud O, Lachkar S, Mou H, Doti N, Fimia GM, Lam NV, Zhu C, Godin I, Muller K, Chatzi A, Nuebel E, Ciccosanti F, Flamant S, Benit P, Perfettini JL, Sauvat A, Bennaceur-Griscelli A, Ser-Le Roux K, Gonin P, Tokatlidis K, Rustin P, Piacentini M, Ruvo M, Blomgren K, Kroemer G, Modjtahedi N, Interaction between AIF and CHCHD4 Regulates Respiratory Chain Biogenesis. Mol Cell. 2015 Jun 18;58(6):1001-14
2	J:135191 Ishimura R, Martin GR, Ackerman SL, Loss of apoptosis-inducing factor results in cell-type-specific neurogenesis defects. J Neurosci. 2008 May 7;28(19):4938-48
4	J:243635 Khacho M, Clark A, Svoboda DS, MacLaurin JG, Lagace DC, Park DS, Slack RS, Mitochondrial dysfunction underlies cognitive defects as a result of neural stem cell depletion and impaired neurogenesis. Hum Mol Genet. 2017 Sep 01;26(17):3327-3341
2*	J:181599 Martin-Oliva D, Ferrer-Martin RM, Santos AM, Carrasco MC, Sierra A, Marin-Teva JL, Calvente R, Navascues J, Cuadros MA, Simultaneous cell death and upregulation of poly(ADP-ribose) polymerase-1 expression in early postnatal mouse retina. Invest Ophthalmol Vis Sci. 2011 Sep;52(10):7445-54
4*	J:311146 Murata H, Sunohara M, Sato I, Expression of DMP1 in the developing mouse tongue embryo. Ann Anat. 2015 Jul;200:136-48
2	J:312376 Pastar V, Lozic M, Kelam N, Filipovic N, Bernard B, Katsuyama Y, Vukojevic K, Connexin Expression Is Altered in Liver Development of Yotari (dab1 -/-) Mice. Int J Mol Sci. 2021 Oct 2;22(19)
1*	J:180513 Posey KL, Coustry F, Veerisetty AC, Liu P, Alcorn JL, Hecht JT, Chop (Ddit3) Is Essential for D469del-COMP Retention and Cell Death in Chondrocytes in an Inducible Transgenic Mouse Model of Pseudoachondroplasia. Am J Pathol. 2012 Feb;180(2):727-37
2	J:317438 Sheng X, Liu C, Yan G, Li G, Liu J, Yang Y, Li S, Li Z, Zhou J, Zhen X, Zhang Y, Diao Z, Hu Y, Fu C, Yao B, Li C, Cao Y, Lu B, Yang Z, Qin Y, Sun H, Ding L, The mitochondrial protease LONP1 maintains oocyte development and survival by suppressing nuclear translocation of AIFM1 in mammals. EBioMedicine. 2021 Dec 30;75:103790
2*	J:174767 Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA, Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
1*	J:344117 Wang S, Matsumoto K, Mehlferber MM, Zhang G, Aronova MA, Yamada KM, Microtubule-dependent apical polarization of basement membrane matrix mRNAs in mouse epithelial cells. Cells Dev. 2023 Dec 14;177:203898
1	J:146172 Wang X, Rao RP, Kosakowska-Cholody T, Masood MA, Southon E, Zhang H, Berthet C, Nagashim K, Veenstra TK, Tessarollo L, Acharya U, Acharya JK, Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice. J Cell Biol. 2009 Jan 12;184(1):143-58
1*	J:209127 Zaltsman Y, Shachnai L, Yivgi-Ohana N, Schwarz M, Maryanovich M, Houtkooper RH, Vaz FM, De Leonardis F, Fiermonte G, Palmieri F, Gillissen B, Daniel PT, Jimenez E, Walsh S, Koehler CM, Roy SS, Walter L, Hajnoczky G, Gross A, MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria. Nat Cell Biol. 2010 Jun;12(6):553-62