Symbol Name ID |
Dpysl2
dihydropyrimidinase-like 2 MGI:1349763 |
Age | E7 | E10 | E10.5 | E11 | E11.5 | E12 | E12.5 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E18.5 | E | P |
Immunohistochemistry (section) | 1 | 1 | 2 | 2 | 1 | 3 | 3 | |||||||||||
In situ RNA (section) | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 3 | |||||||||
Northern blot | 1 | 1 | 1 | 1 | 1 | 2 | ||||||||||||
Western blot | 1 | 1 | 5 | 1 | 1 | 3 | 7 |
Dpysl2 dihydropyrimidinase-like 2 (Synonyms: Crmp2, DRP2, TOAD-64, Ulip2) | |
Results | Reference |
1 | J:221787 Arbeille E, Reynaud F, Sanyas I, Bozon M, Kindbeiter K, Causeret F, Pierani A, Falk J, Moret F, Castellani V, Cerebrospinal fluid-derived Semaphorin3B orients neuroepithelial cell divisions in the apicobasal axis. Nat Commun. 2015;6:6366 |
1* | J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034 |
1 | J:317793 De Zio D, Molinari F, Rizza S, Gatta L, Ciotti MT, Salvatore AM, Mathiassen SG, Cwetsch AW, Filomeni G, Rosano G, Ferraro E, Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth. Cell Mol Life Sci. 2015 Nov;72(21):4173-91 |
2 | J:345844 Guo Y, Xiang P, Sun X, Liu W, Zhou J, Yin B, Hou L, Qiang B, Li H, Shu P, Peng X, Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy. Signal Transduct Target Ther. 2024 Feb 14;9(1):32 |
1 | J:230934 Hashimoto M, Murata K, Ishida J, Kanou A, Kasuya Y, Fukamizu A, Severe Hypomyelination and Developmental Defects Are Caused in Mice Lacking Protein Arginine Methyltransferase 1 (PRMT1) in the Central Nervous System. J Biol Chem. 2016 Jan 29;291(5):2237-45 |
7 | J:63333 Inagaki H, Kato Y, Hamajima N, Nonaka M, Sasaki M, Eimoto T, Differential expression of dihydropyrimidinase-related protein genes in developing and adult enteric nervous system. Histochem Cell Biol. 2000 Jan;113(1):37-41 |
1 | J:180317 Ip JP, Shi L, Chen Y, Itoh Y, Fu WY, Betz A, Yung WH, Gotoh Y, Fu AK, Ip NY, alpha2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2. Nat Neurosci. 2012 Jan;15(1):39-47 |
5* | J:65419 Ito T, Kagoshima M, Sasaki Y, Li C, Udaka N, Kitsukawa T, Fujisawa H, Taniguchi M, Yagi T, Kitamura H, Goshima Y, Repulsive axon guidance molecule Sema3A inhibits branching morphogenesis of fetal mouse lung. Mech Dev. 2000 Oct;97(1-2):35-45 |
8* | J:47185 Kamata T, Subleski M, Hara Y, Yuhki N, Kung H, Copeland NG, Jenkins NA, Yoshimura T, Modi W, Copeland TD, Isolation and characterization of a bovine neural specific protein (CRMP-2) cDNA homologous to unc-33, a C. elegans gene implicated in axonal outgrowth and guidance. Brain Res Mol Brain Res. 1998 Mar 1;54(2):219-36 |
1 | J:340777 Laddach A, Chng SH, Lasrado R, Progatzky F, Shapiro M, Erickson A, Sampedro Castaneda M, Artemov AV, Bon-Frauches AC, Amaniti EM, Kleinjung J, Boeing S, Ultanir S, Adameyko I, Pachnis V, A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia. Nat Commun. 2023 Sep 22;14(1):5904 |
3* | J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86 |
1 | J:269440 Morgan-Smith M, Wu Y, Zhu X, Pringle J, Snider WD, GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation. Elife. 2014 Jul 29;3:e02663 |
1* | J:208048 Tortoriello G, Morris CV, Alpar A, Fuzik J, Shirran SL, Calvigioni D, Keimpema E, Botting CH, Reinecke K, Herdegen T, Courtney M, Hurd YL, Harkany T, Miswiring the brain: Delta9-tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin-2 degradation pathway. EMBO J. 2014 Apr 1;33(7):668-85 |
8* | J:155713 Uchida Y, Ohshima T, Yamashita N, Ogawara M, Sasaki Y, Nakamura F, Goshima Y, Semaphorin3A signaling mediated by Fyn-dependent tyrosine phosphorylation of collapsin response mediator protein 2 at tyrosine 32. J Biol Chem. 2009 Oct 2;284(40):27393-401 |
1* | J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6 |
5 | J:293780 Yamazaki Y, Nagai J, Akinaga S, Koga Y, Hasegawa M, Takahashi M, Yamashita N, Kolattukudy P, Goshima Y, Ohshima T, Phosphorylation of CRMP2 is required for migration and positioning of Purkinje cells: Redundant roles of CRMP1 and CRMP4. Brain Res. 2020 Jun 1;1736:146762 |
1 | J:276149 Zhu R, Pan YH, Sun L, Zhang T, Wang C, Ye S, Yang N, Lu T, Wisniewski T, Dang S, Zhang W, ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice. Neuroscience. 2019 Feb 10;399:53-64 |
3 | J:285782 Ziak J, Weissova R, Jerabkova K, Janikova M, Maimon R, Petrasek T, Pukajova B, Kleisnerova M, Wang M, Brill MS, Kasparek P, Zhou X, Alvarez-Bolado G, Sedlacek R, Misgeld T, Stuchlik A, Perlson E, Balastik M, CRMP2 mediates Sema3F-dependent axon pruning and dendritic spine remodeling. EMBO Rep. 2020 Mar 4;21(3):e48512 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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