Gene Expression Literature Summary

• Symbol: Trp53bp1
• Name: transformation related protein 53 binding protein 1
• ID: MGI:1351320

39 matching records from 39 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E2	E2.5	E5.5	E6.5	E8.5	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16	E16.5	E17.5	E18.5	E	P
Immunohistochemistry (section)			1	1	1	1	1	4	3	3	3	2	1	2	3		2	13
In situ RNA (section)											3	1						1
Immunohistochemistry (whole mount)	1	1																1
Western blot									1									1
RT-PCR										1						1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Trp53bp1  transformation related protein 53 binding protein 1   (Synonyms: 53BP1, p53BP1)
Results	Reference
3*	J:233378 Barazzuol L, Rickett N, Ju L, Jeggo PA, Low levels of endogenous or X-ray-induced DNA double-strand breaks activate apoptosis in adult neural stem cells. J Cell Sci. 2015 Oct 1;128(19):3597-606
1	J:208632 Bazzi H, Anderson KV, Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):E1491-500
2	J:100324 Bulfone A, Carotenuto P, Faedo A, Aglio V, Garzia L, Bello AM, Basile A, Andre A, Cocchia M, Guardiola O, Ballabio A, Rubenstein JL, Zollo M, Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes. J Neurosci. 2005 Aug 17;25(33):7586-600
2	J:154193 Cao L, Xu X, Bunting SF, Liu J, Wang RH, Cao LL, Wu JJ, Peng TN, Chen J, Nussenzweig A, Deng CX, Finkel T, A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency. Mol Cell. 2009 Aug 28;35(4):534-41
1	J:245759 Casoni F, Croci L, Bosone C, D'Ambrosio R, Badaloni A, Gaudesi D, Barili V, Sarna JR, Tessarollo L, Cremona O, Hawkes R, Warming S, Consalez GG, Zfp423/ZNF423 regulates cell cycle progression, the mode of cell division and the DNA-damage response in Purkinje neuron progenitors. Development. 2017 Oct 15;144(20):3686-3697
1	J:171415 Castro DS, Martynoga B, Parras C, Ramesh V, Pacary E, Johnston C, Drechsel D, Lebel-Potter M, Garcia LG, Hunt C, Dolle D, Bithell A, Ettwiller L, Buckley N, Guillemot F, A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets. Genes Dev. 2011 May 1;25(9):930-45
1	J:325357 Chomiak AA, Guo Y, Kopsidas CA, McDaniel DP, Lowe CC, Pan H, Zhou X, Zhou Q, Doughty ML, Feng Y, Nde1 is required for heterochromatin compaction and stability in neocortical neurons. iScience. 2022 Jun 17;25(6):104354
1	J:307645 Dai XX, Jiang Y, Gu JH, Jiang ZY, Wu YW, Yu C, Yin H, Zhang J, Shi QH, Shen L, Sha QQ, Fan HY, The CNOT4 Subunit of the CCR4-NOT Complex is Involved in mRNA Degradation, Efficient DNA Damage Repair, and XY Chromosome Crossover during Male Germ Cell Meiosis. Adv Sci (Weinh). 2021 May;8(10):2003636
1	J:306061 Damen M, Wirtz L, Soroka E, Khatif H, Kukat C, Simons BD, Bazzi H, High proliferation and delamination during skin epidermal stratification. Nat Commun. 2021 May 28;12(1):3227
1	J:141953 Derradji H, Bekaert S, De Meyer T, Jacquet P, Abou-El-Ardat K, Ghardi M, Arlette M, Baatout S, Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects. Dev Biol. 2008 Aug 7;322(2):302-313
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3*	J:174554 Gatz SA, Ju L, Gruber R, Hoffmann E, Carr AM, Wang ZQ, Liu C, Jeggo PA, Requirement for DNA ligase IV during embryonic neuronal development. J Neurosci. 2011 Jul 6;31(27):10088-100
1*	J:217609 Goggolidou P, Stevens JL, Agueci F, Keynton J, Wheway G, Grimes DT, Patel SH, Hilton H, Morthorst SK, DiPaolo A, Williams DJ, Sanderson J, Khoronenkova SV, Powles-Glover N, Ermakov A, Esapa CT, Romero R, Dianov GL, Briscoe J, Johnson CA, Pedersen LB, Norris DP, ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis. Development. 2014 Oct;141(20):3966-77
1	J:175792 Jelcick AS, Yuan Y, Leehy BD, Cox LC, Silveira AC, Qiu F, Schenk S, Sachs AJ, Morrison MA, Nystuen AM, DeAngelis MM, Haider NB, Genetic variations strongly influence phenotypic outcome in the mouse retina. PLoS One. 2011;6(7):e21858
1	J:326251 Kalogeropoulou A, Mougkogianni M, Iliadou M, Nikolopoulou E, Flordelis S, Kanellou A, Arbi M, Nikou S, Nieminuszczy J, Niedzwiedz W, Kardamakis D, Bravou V, Lygerou Z, Taraviras S, Intrinsic neural stem cell properties define brain hypersensitivity to genotoxic stress. Stem Cell Reports. 2022 Jun 14;17(6):1395-1410
1	J:331939 Keil JM, Doyle DZ, Qalieh A, Lam MM, Funk OH, Qalieh Y, Shi L, Mohan N, Sorel A, Kwan KY, Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80. Nat Commun. 2020 Jul 31;11(1):3839
1	J:159668 Kim GJ, Georg I, Scherthan H, Merkenschlager M, Guillou F, Scherer G, Barrionuevo F, Dicer is required for Sertoli cell function and survival. Int J Dev Biol. 2010;54(5):867-75
1	J:252381 Kokavec J, Zikmund T, Savvulidi F, Kulvait V, Edelmann W, Skoultchi AI, Stopka T, The ISWI ATPase Smarca5 (Snf2h) Is Required for Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells. Stem Cells. 2017 Jun;35(6):1614-1623
1	J:152528 Lee Y, Katyal S, Li Y, El-Khamisy SF, Russell HR, Caldecott KW, McKinnon PJ, The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1. Nat Neurosci. 2009 Aug;12(8):973-80
1*	J:347585 Leon NY, Le TNU, Garvie A, Wong LH, Bagheri-Fam S, Harley VR, Y chromosome damage underlies testicular abnormalities in ATR-X syndrome. iScience. 2024 May 17;27(5):109629
1*	J:173286 Long JE, Cobos I, Potter GB, Rubenstein JL, Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Cereb Cortex. 2009 Jul;19 Suppl 1:i96-106
1	J:288654 Lun MP, Shannon ML, Keles S, Reisli I, Luche N, Ryan D, Capuder K, Notarangelo LD, Lehtinen MK, Spatiotemporal Gradient of Cortical Neuron Death Contributes to Microcephaly in Knock-In Mouse Model of Ligase 4 Syndrome. Am J Pathol. 2019 Dec;189(12):2440-2449
1	J:229930 Nechiporuk T, McGann J, Mullendorff K, Hsieh J, Wurst W, Floss T, Mandel G, The REST remodeling complex protects genomic integrity during embryonic neurogenesis. Elife. 2016;5:e09584
1	J:219210 Nikolaou KC, Moulos P, Chalepakis G, Hatzis P, Oda H, Reinberg D, Talianidis I, Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers. EMBO J. 2015 Feb 12;34(4):430-47
3	J:147765 Oda H, Okamoto I, Murphy N, Chu J, Price SM, Shen MM, Torres-Padilla ME, Heard E, Reinberg D, Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development. Mol Cell Biol. 2009 Apr;29(8):2278-95
1*	J:331871 Rodriguez A, Epperly M, Filiatrault J, Velazquez M, Yang C, McQueen K, Sambel LA, Nguyen H, Iyer DR, Juarez U, Ayala-Zambrano C, Martignetti DB, Frias S, Fisher R, Parmar K, Greenberger JS, D'Andrea AD, TGFbeta pathway is required for viable gestation of Fanconi anemia embryos. PLoS Genet. 2022 Nov;18(11):e1010459
1	J:197673 Saxe JP, Chen M, Zhao H, Lin H, Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline. EMBO J. 2013 Jul 3;32(13):1869-85
1	J:203136 Solomon LA, Russell BA, Watson LA, Beier F, Berube NG, Targeted loss of the ATR-X syndrome protein in the limb mesenchyme of mice causes brachydactyly. Hum Mol Genet. 2013 Dec 15;22(24):5015-25
1	J:192592 Sotiropoulou PA, Karambelas AE, Debaugnies M, Candi A, Bouwman P, Moers V, Revenco T, Rocha AS, Sekiguchi K, Jonkers J, Blanpain C, BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny. Genes Dev. 2013 Jan 1;27(1):39-51
1	J:333324 Tominaga K, Sakashita E, Kasashima K, Kuroiwa K, Nagao Y, Iwamori N, Endo H, Tip60/KAT5 Histone Acetyltransferase Is Required for Maintenance and Neurogenesis of Embryonic Neural Stem Cells. Int J Mol Sci. 2023 Jan 20;24(3)
1	J:299668 Uyeda A, Onishi K, Hirayama T, Hattori S, Miyakawa T, Yagi T, Yamamoto N, Sugo N, Suppression of DNA Double-Strand Break Formation by DNA Polymerase beta in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons. J Neurosci. 2020 Nov 18;40(47):9012-9027
1	J:351707 Wen C, Cao L, Wang S, Xu W, Yu Y, Zhao S, Yang F, Chen ZJ, Zhao S, Yang Y, Qin Y, MCM8 interacts with DDX5 to promote R-loop resolution. EMBO J. 2024 Jul;43(14):3044-3071
3	J:302304 Xiao C, Grzonka M, Meyer-Gerards C, Mack M, Figge R, Bazzi H, Gradual centriole maturation associates with the mitotic surveillance pathway in mouse development. EMBO Rep. 2021 Feb 3;22(2):e51127
1	J:339060 Xu W, Yang Y, Yu Y, Wen C, Zhao S, Cao L, Zhao S, Qin Y, Chen ZJ, FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells. BMC Biol. 2023 Aug 15;21(1):174
1	J:241249 Xue Y, Raharja A, Sim W, Wong ES, Rahmat SA, Lane DP, The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage. Oncogene. 2017 Apr 06;36(14):2002-2013
1	J:327430 Yang Y, Xu W, Gao F, Wen C, Zhao S, Yu Y, Jiao W, Mi X, Qin Y, Chen ZJ, Zhao S, Transcription-replication conflicts in primordial germ cells necessitate the Fanconi anemia pathway to safeguard genome stability. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2203208119
5	J:328457 Yin H, Suye S, Zhou Z, Cai H, Fu C, The reduction of oocytes and disruption of the meiotic prophase I in Fanconi anemia E-deficient mice. Reproduction. 2022 Sep 1;164(3):71-82
1	J:333722 Zhao S, Huang C, Yang Y, Xu W, Yu Y, Wen C, Cao L, Gao F, Qin Y, Chen ZJ, Guo T, Zhao S, DNA repair protein FANCD2 has both ubiquitination-dependent and ubiquitination-independent functions during germ cell development. J Biol Chem. 2023 Jan 13;299(3):102905
1	J:261356 Zhou ZW, Tapias A, Bruhn C, Gruber R, Sukchev M, Wang ZQ, DNA damage response in microcephaly development of MCPH1 mouse model. DNA Repair (Amst). 2013 Aug;12(8):645-55