Gene Expression Literature Summary

• Symbol: Casr
• Name: calcium-sensing receptor
• ID: MGI:1351351

15 matching records from 15 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E10.5	E11	E11.5	E12.5	E13.5	E14.5	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	P
Immunohistochemistry (section)	1		1	3	1	1			1				1	2
In situ RNA (section)	1		2	1	1		1				1		1	3
In situ RNA (whole mount)	1	1
Western blot								1				1		1
RT-PCR			2	1	2	2	1	1	1	1	1	1	2	6
cDNA clones			1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Casr  calcium-sensing receptor   (Synonyms: CaR, cation sensing receptor, Gprc2a)
Results	Reference
3	J:101530 Bowl MR, Nesbit MA, Harding B, Levy E, Jefferson A, Volpi E, Rizzoti K, Lovell-Badge R, Schlessinger D, Whyte MP, Thakker RV, An interstitial deletion-insertion involving chromosomes 2p25.3 and Xq27.1, near SOX3, causes X-linked recessive hypoparathyroidism. J Clin Invest. 2005 Oct;115(10):2822-31
1*	J:193589 Finney B, Wilkinson WJ, Searchfield L, Cole M, Bailey S, Kemp PJ, Riccardi D, An exon 5-less splice variant of the extracellular calcium-sensing receptor rescues absence of the full-length receptor in the developing mouse lung. Exp Lung Res. 2011 Jun;37(5):269-78
17*	J:144077 Finney BA, del Moral PM, Wilkinson WJ, Cayzac S, Cole M, Warburton D, Kemp PJ, Riccardi D, Regulation of mouse lung development by the extracellular calcium-sensing receptor, CaR. J Physiol. 2008 Dec 15;586(Pt 24):6007-19
1	J:161634 Grigorieva IV, Mirczuk S, Gaynor KU, Nesbit MA, Grigorieva EF, Wei Q, Ali A, Fairclough RJ, Stacey JM, Stechman MJ, Mihai R, Kurek D, Fraser WD, Hough T, Condie BG, Manley N, Grosveld F, Thakker RV, Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2. J Clin Invest. 2010 Jun 1;120(6):2144-55
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2	J:245423 Kadmiel M, Matson BC, Espenschied ST, Lenhart PM, Caron KM, Loss of receptor activity-modifying protein 2 in mice causes placental dysfunction and alters PTH1R regulation. PLoS One. 2017;12(7):e0181597
2	J:267148 Kechele DO, Dunworth WP, Trincot CE, Wetzel-Strong SE, Li M, Ma H, Liu J, Caron KM, Endothelial Restoration of Receptor Activity-Modifying Protein 2 Is Sufficient to Rescue Lethality, but Survivors Develop Dilated Cardiomyopathy. Hypertension. 2016 Sep;68(3):667-77
2	J:75520 Kovacs CS, Chafe LL, Woodland ML, McDonald KR, Fudge NJ, Wookey PJ, Calcitropic gene expression suggests a role for the intraplacental yolk sac in maternal-fetal calcium exchange. Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E721-32
2*	J:203695 Lieben L, Stockmans I, Moermans K, Carmeliet G, Maternal hypervitaminosis D reduces fetal bone mass and mineral acquisition and leads to neonatal lethality. Bone. 2013 Nov;57(1):123-31
3*	J:121311 Liu Z, Yu S, Manley NR, Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia. Dev Biol. 2007 May 1;305(1):333-46
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1*	J:280399 Singh A, Mia MM, Cibi DM, Arya AK, Bhadada SK, Singh MK, Deficiency in the secreted protein Semaphorin3d causes abnormal parathyroid development in mice. J Biol Chem. 2019 May 24;294(21):8336-8347
2*	J:147173 Sultana DA, Tomita S, Hamada M, Iwanaga Y, Kitahama Y, Khang NV, Hirai S, Ohigashi I, Nitta S, Amagai T, Takahashi S, Takahama Y, Gene expression profile of the third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus development. Blood. 2009 Mar 26;113(13):2976-87
7*	J:135350 Vizard TN, O'Keeffe GW, Gutierrez H, Kos CH, Riccardi D, Davies AM, Regulation of axonal and dendritic growth by the extracellular calcium-sensing receptor. Nat Neurosci. 2008 Mar;11(3):285-91
1	J:273271 Yamada T, Tatsumi N, Anraku A, Suzuki H, Kamejima S, Uchiyama T, Ohkido I, Yokoo T, Okabe M, Gcm2 regulates the maintenance of parathyroid cells in adult mice. PLoS One. 2019;14(1):e0210662