Gene Expression Literature Summary

• Symbol: Eif2ak2
• Name: eukaryotic translation initiation factor 2-alpha kinase 2
• ID: MGI:1353449

6 matching records from 6 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E10.5	E11	E11.5	E13.5	E15	E17	E18.5	P
Immunohistochemistry (section)						1
In situ RNA (section)					1				1
Western blot		1						1
RT-PCR	1		1	1	1	1	1		2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Eif2ak2  eukaryotic translation initiation factor 2-alpha kinase 2   (Synonyms: 2310047A08Rik, 4732414G15Rik, dsRNA-activated kinase, eIF-2 alpha, eIF-2 alpha, IFN-induced and double-stranded RNA-activated kinase, IFN- type I-induced and dsRNA-activated kinase, Pkr, Prkr, Tik)
Results	Reference
5*	J:118001 Baltzis D, Li S, Koromilas AE, Functional characterization of pkr gene products expressed in cells from mice with a targeted deletion of the N terminus or C terminus domain of PKR. J Biol Chem. 2002 Oct 11;277(41):38364-72
1	J:305864 Kalish BT, Kim E, Finander B, Duffy EE, Kim H, Gilman CK, Yim YS, Tong L, Kaufman RJ, Griffith EC, Choi GB, Greenberg ME, Huh JR, Maternal immune activation in mice disrupts proteostasis in the fetal brain. Nat Neurosci. 2021 Feb;24(2):204-213
1*	J:265968 Mannion NM, Greenwood SM, Young R, Cox S, Brindle J, Read D, Nellaker C, Vesely C, Ponting CP, McLaughlin PJ, Jantsch MF, Dorin J, Adams IR, Scadden AD, Ohman M, Keegan LP, O'Connell MA, The RNA-editing enzyme ADAR1 controls innate immune responses to RNA. Cell Rep. 2014 Nov 20;9(4):1482-94
4*	J:103446 McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA, A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14
1*	J:321240 Morimoto H, Baba R, Haneji T, Doi Y, Double-stranded RNA-dependent protein kinase regulates insulin-stimulated chondrogenesis in mouse clonal chondrogenic cells, ATDC-5. Cell Tissue Res. 2013 Jan;351(1):41-7
1	J:354587 Nedomova M, Haberecht-Muller S, Moller S, Venz S, Prochazkova M, Prochazka J, Sedlak F, Chawengsaksophak K, Hammer E, Kasparek P, Adamek M, Sedlacek R, Konvalinka J, Kruger E, Grantz Saskova K, DDI2 protease controls embryonic development and inflammation via TCF11/NRF1. iScience. 2024 Oct 18;27(10):110893