Gene Expression Literature Summary

• Symbol: Tor1a
• Name: torsin family 1, member A (torsin A)
• ID: MGI:1353568

7 matching records from 7 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E10.5	E11	E11.5	E12.5	E13	E14.5	E15	E15.5	E16	E17	E17.5	E18	E18.5	P
Immunohistochemistry (section)														1
Northern blot		1			1					1				2
Western blot	1	1	1	1	1	1	1	1	1	2	1	2	2	5
RT-PCR				1				1					1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tor1a  torsin family 1, member A (torsin A)   (Synonyms: DQ2, Dyt1, Tor1a, torsinA)
Results	Reference
7	J:263180 Dominguez Gonzalez B, Billion K, Rous S, Pavie B, Lange C, Goodchild R, Excess LINC complexes impair brain morphogenesis in a mouse model of recessive TOR1A disease. Hum Mol Genet. 2018 Jun 15;27(12):2154-2170
5*	J:107596 Goodchild RE, Kim CE, Dauer WT, Loss of the dystonia-associated protein torsinA selectively disrupts the neuronal nuclear envelope. Neuron. 2005 Dec 22;48(6):923-32
5*	J:157110 Jungwirth M, Dear ML, Brown P, Holbrook K, Goodchild R, Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinA. Hum Mol Genet. 2010 Mar 1;19(5):888-900
2	J:160544 Kim CE, Perez A, Perkins G, Ellisman MH, Dauer WT, A molecular mechanism underlying the neural-specific defect in torsinA mutant mice. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9861-6
1	J:226849 Ruiz M, Perez-Garcia G, Ortiz-Virumbrales M, Meneret A, Morant A, Kottwitz J, Fuchs T, Bonet J, Gonzalez-Alegre P, Hof PR, Ozelius LJ, Ehrlich ME, Abnormalities of motor function, transcription and cerebellar structure in mouse models of THAP1 dystonia. Hum Mol Genet. 2015 Dec 20;24(25):7159-70
9*	J:106947 Vasudevan A, Breakefield XO, Bhide PG, Developmental patterns of torsinA and torsinB expression. Brain Res. 2006 Feb 16;1073-1074C:139-145
1	J:255264 Zhang J, Weinrich JAP, Russ JB, Comer JD, Bommareddy PK, DiCasoli RJ, Wright CVE, Li Y, van Roessel PJ, Kaltschmidt JA, A Role for Dystonia-Associated Genes in Spinal GABAergic Interneuron Circuitry. Cell Rep. 2017 Oct 17;21(3):666-678