Gene Expression Literature Summary

• Symbol: E2f6
• Name: E2F transcription factor 6
• ID: MGI:1354159

21 matching records from 21 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E1.5	E2	E2.5	E3	E3.5	E4.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E18	E18.5	E20	E	P
Immunohistochemistry (section)										1				1
In situ RNA (section)												1			1	3		1	1	2					1			2
In situ RNA (whole mount)								1		3		1	1							2
Northern blot							1		1		1		1		1		1		1		1		1	1				1
Western blot								1		1		1		1		1		1			1	1			1	1		4
RT-PCR	1	1	1	1	2	1			2	1			1			2	1	1						2				6
cDNA clones																												1
RNase protection																											1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

E2f6  E2F transcription factor 6   (Synonyms: EMA)
Results	Reference
3*	J:314268 Akagawa R, Nabeshima YI, Kawauchi T, Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons. Front Cell Dev Biol. 2021;9:753175
4*	J:171293 Campbell GR, Baudhuin A, Vranizan K, Ngai J, Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling. Mol Cell Neurosci. 2011 Feb;46(2):548-61
2*	J:307865 Dahlet T, Truss M, Frede U, Al Adhami H, Bardet AF, Dumas M, Vallet J, Chicher J, Hammann P, Kottnik S, Hansen P, Luz U, Alvarez G, Auclair G, Hecht J, Robinson PN, Hagemeier C, Weber M, E2F6 initiates stable epigenetic silencing of germline genes during embryonic development. Nat Commun. 2021 Jun 11;12(1):3582
2	J:123395 Deshpande AM, Akunowicz JD, Reveles XT, Patel BB, Saria EA, Gorlick RG, Naylor SL, Leach RJ, Hansen MF, PHC3, a component of the hPRC-H complex, associates with E2F6 during G0 and is lost in osteosarcoma tumors. Oncogene. 2007 Mar 15;26(12):1714-22
1*	J:152838 Fu H, Cai J, Clevers H, Fast E, Gray S, Greenberg R, Jain MK, Ma Q, Qiu M, Rowitch DH, Taylor CM, Stiles CD, A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. J Neurosci. 2009 Sep 9;29(36):11399-408
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1	J:332407 Gu Y, Zhou Y, Ju S, Liu X, Zhang Z, Guo J, Gao J, Zang J, Sun H, Chen Q, Wang J, Xu J, Xu Y, Chen Y, Guo Y, Dai J, Ma H, Wang C, Jin G, Li C, Xia Y, Shen H, Yang Y, Guo X, Hu Z, Multi-omics profiling visualizes dynamics of cardiac development and functions. Cell Rep. 2022 Dec 27;41(13):111891
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
7*	J:140465 Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P, Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85
14*	J:72430 Kherrouche Z, Begue A, Stehelin D, Monte D, Molecular cloning and characterization of the mouse e2f6 gene. Biochem Biophys Res Commun. 2001 Oct 19;288(1):22-33
9*	J:63376 Kusek JC, Greene RM, Nugent P, Pisano MM, Expression of the E2F family of transcription factors during murine development. Int J Dev Biol. 2000 Apr;44(3):267-77
7*	J:86704 Maynard TM, Haskell GT, Peters AZ, Sikich L, Lieberman JA, LaMantia AS, A comprehensive analysis of 22q11 gene expression in the developing and adult brain. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14433-8
1	J:311151 Nakano T, Aochi H, Hirasaki M, Takenaka Y, Fujita K, Tamura M, Soma H, Kamezawa H, Koizumi T, Shibuya H, Inomata R, Okuda A, Murakoshi T, Shimada A, Inoue I, Effects of Ppargamma1 deletion on late-stage murine embryogenesis and cells that undergo endocycle. Dev Biol. 2021 Oct;478:222-235
1*	J:153105 Tallack MR, Keys JR, Humbert PO, Perkins AC, EKLF/KLF1 controls cell cycle entry via direct regulation of E2f2. J Biol Chem. 2009 Jul 31;284(31):20966-74
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1*	J:228946 Wei N, Cheng Y, Wang Z, Liu Y, Luo C, Liu L, Chen L, Xie Z, Lu Y, Feng Y, SRSF10 Plays a Role in Myoblast Differentiation and Glucose Production via Regulation of Alternative Splicing. Cell Rep. 2015 Nov 24;13(8):1647-57
2	J:117307 Wenzel PL, Wu L, de Bruin A, Chong JL, Chen WY, Dureska G, Sites E, Pan T, Sharma A, Huang K, Ridgway R, Mosaliganti K, Sharp R, Machiraju R, Saltz J, Yamamoto H, Cross JC, Robinson ML, Leone G, Rb is critical in a mammalian tissue stem cell population. Genes Dev. 2007 Jan 1;21(1):85-97
3*	J:187480 Westendorp B, Major JL, Nader M, Salih M, Leenen FH, Tuana BS, The E2F6 repressor activates gene expression in myocardium resulting in dilated cardiomyopathy. FASEB J. 2012 Jun;26(6):2569-79
1*	J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
3*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48