Gene Expression Literature Summary

• Symbol: Mapk6
• Name: mitogen-activated protein kinase 6
• ID: MGI:1354946

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9	E9.5	E11	E11.5	E12.5	E13	E13.5	E14.5	E15	E15.5	E16.5	E17	E18.5	P
In situ RNA (section)			1		1			5			1
In situ RNA (whole mount)										1
In situ reporter (knock in)										1
Northern blot	1		1			1			1			1		1
Western blot			1		1	1			1			1		3
RT-PCR		2		2	1		1			1	1		3	1
cDNA clones														1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Mapk6  mitogen-activated protein kinase 6   (Synonyms: 2610021I23Rik, D130053K17Rik, Erk3, ERK3, Mapk4, Mapk63, Prkm4, Prkm6)
Results	Reference
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
3	J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20
3*	J:180468 Kant S, Schumacher S, Singh MK, Kispert A, Kotlyarov A, Gaestel M, Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5. J Biol Chem. 2006 Nov 17;281(46):35511-9
2*	J:153218 Klinger S, Turgeon B, Levesque K, Wood GA, Aagaard-Tillery KM, Meloche S, Loss of Erk3 function in mice leads to intrauterine growth restriction, pulmonary immaturity, and neonatal lethality. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16710-5
2	J:344102 Racedo SE, Liu Y, Shi L, Zheng D, Morrow BE, Dgcr8 functions in the secondary heart field for outflow tract and right ventricle development in mammals. Dev Biol. 2024 Feb;506:72-84
6*	J:219480 Rousseau J, Klinger S, Rachalski A, Turgeon B, Deleris P, Vigneault E, Poirier-Heon JF, Davoli MA, Mechawar N, El Mestikawy S, Cermakian N, Meloche S, Targeted inactivation of Mapk4 in mice reveals specific nonredundant functions of Erk3/Erk4 subfamily mitogen-activated protein kinases. Mol Cell Biol. 2010 Dec;30(24):5752-63
2*	J:94780 Schumacher S, Laass K, Kant S, Shi Y, Visel A, Gruber AD, Kotlyarov A, Gaestel M, Scaffolding by ERK3 regulates MK5 in development. EMBO J. 2004 Dec 8;23(24):4770-4779
3	J:294106 Soulez M, Saba-El-Leil MK, Turgeon B, Mathien S, Coulombe P, Klinger S, Rousseau J, Levesque K, Meloche S, Reevaluation of the Role of Extracellular Signal-Regulated Kinase 3 in Perinatal Survival and Postnatal Growth Using New Genetically Engineered Mouse Models. Mol Cell Biol. 2019 Mar 15;39(6)
12*	J:60713 Turgeon B, Saba-El-Leil MK, Meloche S, Cloning and characterization of mouse extracellular-signal-regulated protein kinase 3 as a unique gene product of 100 kDa. Biochem J. 2000 Feb 15;346 Pt 1:169-75
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6