Symbol Name ID |
Hnrnpu
heterogeneous nuclear ribonucleoprotein U MGI:1858195 |
Age | E1 | E2 | E6.5 | E7.5 | E8.5 | E9.5 | E10.5 | E12.5 | E13 | E14.5 | E15.5 | E17 | E17.5 | E18.5 | E | P |
Immunohistochemistry (section) | 1 | 1 | 1 | 1 | 1 | 1 | 3 | |||||||||
In situ RNA (section) | 1 | |||||||||||||||
Immunohistochemistry (whole mount) | 1 | 1 | 1 | |||||||||||||
In situ RNA (whole mount) | 1 | 1 | 1 | 1 | ||||||||||||
Western blot | 2 | 2 | ||||||||||||||
RT-PCR | 1 | 1 | 3 | 2 |
Hnrnpu heterogeneous nuclear ribonucleoprotein U (Synonyms: Hnrpu, scaffold attachment factor A, Sp120) | |
Results | Reference |
2* | J:176460 Ayoub AE, Oh S, Xie Y, Leng J, Cotney J, Dominguez MH, Noonan JP, Rakic P, Transcriptional programs in transient embryonic zones of the cerebral cortex defined by high-resolution mRNA sequencing. Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14950-5 |
1 | J:185743 Cotney J, Leng J, Oh S, DeMare LE, Reilly SK, Gerstein MB, Noonan JP, Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb. Genome Res. 2012 Jun;22(6):1069-80 |
1 | J:185205 Heisig J, Weber D, Englberger E, Winkler A, Kneitz S, Sung WK, Wolf E, Eilers M, Wei CL, Gessler M, Target gene analysis by microarrays and chromatin immunoprecipitation identifies HEY proteins as highly redundant bHLH repressors. PLoS Genet. 2012 May;8(5):e1002728 |
3 | J:326958 Sapir T, Kshirsagar A, Gorelik A, Olender T, Porat Z, Scheffer IE, Goldstein DB, Devinsky O, Reiner O, Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex. Nat Commun. 2022 Jul 21;13(1):4209 |
4* | J:85124 Sousa-Nunes R, Rana AA, Kettleborough R, Brickman JM, Clements M, Forrest A, Grimmond S, Avner P, Smith JC, Dunwoodie SL, Beddington RS, Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection. Genome Res. 2003 Dec;13(12):2609-20 |
1* | J:310343 Valdez-Sinon AN, Lai A, Shi L, Lancaster CL, Gokhale A, Faundez V, Bassell GJ, Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism. iScience. 2020 May 22;23(5):101132 |
2 | J:318869 Wang J, Li X, Wang L, Li J, Zhao Y, Bou G, Li Y, Jiao G, Shen X, Wei R, Liu S, Xie B, Lei L, Li W, Zhou Q, Liu Z, A novel long intergenic noncoding RNA indispensable for the cleavage of mouse two-cell embryos. EMBO Rep. 2016 Oct;17(10):1452-1470 |
4 | J:316132 Wen Y, Ma X, Wang X, Wang F, Dong J, Wu Y, Lv C, Liu K, Zhang Y, Zhang Z, Yuan S, hnRNPU in Sertoli cells cooperates with WT1 and is essential for testicular development by modulating transcriptional factors Sox8/9. Theranostics. 2021;11(20):10030-10046 |
5 | J:347767 Wen Y, Zhou S, Gui Y, Li Z, Yin L, Xu W, Feng S, Ma X, Gan S, Xiong M, Dong J, Cheng K, Wang X, Yuan S, hnRNPU is required for spermatogonial stem cell pool establishment in mice. Cell Rep. 2024 Apr 23;43(4):114113 |
3 | J:223139 Ye J, Beetz N, O'Keeffe S, Tapia JC, Macpherson L, Chen WV, Bassel-Duby R, Olson EN, Maniatis T, hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):E3020-9 |
2 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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