Gene Expression Literature Summary

• Symbol: Ngef
• Name: neuronal guanine nucleotide exchange factor
• ID: MGI:1858414

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E11	E11.5	E12.5	E13	E13.5	E14.5	E15	E15.5	E16.5	E17	E18	E18.5	P
Immunohistochemistry (section)				1										1
In situ RNA (section)			2			1	1		1	1			1	3
Northern blot	1	1			1			1			2			2
Western blot												1		1
RT-PCR				1						1				4
cDNA clones														1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ngef  neuronal guanine nucleotide exchange factor   (Synonyms: ephexin, Tims2)
Results	Reference
1*	J:325730 Ahuja N, Hiltabidle MS, Rajasekhar H, Voss S, Lu SZ, Barlow HR, Cowdin MA, Daniel E, Vaddaraju V, Anandakumar T, Black E, Cleaver O, Maynard C, Endothelial Cyp26b1 restrains murine heart valve growth during development. Dev Biol. 2022 Jun;486:81-95
1	J:226616 Araujo DJ, Anderson AG, Berto S, Runnels W, Harper M, Ammanuel S, Rieger MA, Huang HC, Rajkovich K, Loerwald KW, Dekker JD, Tucker HO, Dougherty JD, Gibson JR, Konopka G, FoxP1 orchestration of ASD-relevant signaling pathways in the striatum. Genes Dev. 2015 Oct 15;29(20):2081-96
1	J:131380 Arlotta P, Molyneaux BJ, Jabaudon D, Yoshida Y, Macklis JD, Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum. J Neurosci. 2008 Jan 16;28(3):622-32
2	J:257637 Chang CJ, Chang MY, Chou SY, Huang CC, Chuang JY, Hsu TI, Chang HF, Wu YH, Wu CC, Morales D, Kania A, Kao TJ, Ephexin1 Is Required for Eph-Mediated Limb Trajectory of Spinal Motor Axons. J Neurosci. 2018 Feb 21;38(8):2043-2056
2*	J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44
1	J:267025 Jung H, Park H, Choi Y, Kang H, Lee E, Kweon H, Roh JD, Ellegood J, Choi W, Kang J, Rhim I, Choi SY, Bae M, Kim SG, Lee J, Chung C, Yoo T, Park H, Kim Y, Ha S, Um SM, Mo S, Kwon Y, Mah W, Bae YC, Kim H, Lerch JP, Paik SB, Kim E, Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice. Nat Neurosci. 2018 Sep;21(9):1218-1228
6*	J:61766 Rodrigues NR, Theodosiou AM, Nesbit MA, Campbell L, Tandle AT, Saranath D, Davies KE, Characterization of Ngef, a novel member of the Dbl family of genes expressed predominantly in the caudate nucleus. Genomics. 2000 Apr 1;65(1):53-61
3	J:167656 Shi L, Butt B, Ip FC, Dai Y, Jiang L, Yung WH, Greenberg ME, Fu AK, Ip NY, Ephexin1 is required for structural maturation and neurotransmission at the neuromuscular junction. Neuron. 2010 Jan 28;65(2):204-16
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
2*	J:96550 Williams TM, Williams ME, Kuick R, Misek D, McDonagh K, Hanash S, Innis JW, Candidate downstream regulated genes of HOX group 13 transcription factors with and without monomeric DNA binding capability. Dev Biol. 2005 Mar 15;279(2):462-80
1*	J:281175 Yorgan TA, Peters S, Amling M, Schinke T, Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling. Bone. 2019 Oct;127:155-163
4*	J:84356 Yoshizawa M, Sone M, Matsuo N, Nagase T, Ohara O, Nabeshima Y, Hoshino M, Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain. Gene Expr Patterns. 2003 Jun;3(3):375-81