Gene Expression Literature Summary

• Symbol: Lpar2
• Name: lysophosphatidic acid receptor 2
• ID: MGI:1858422

16 matching records from 16 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E8.5	E9.5	E10.5	E11.5	E12.5	E13.5	E14	E14.5	E15.5	E16	E18	E19	P
Immunohistochemistry (section)											1			1
In situ RNA (section)					1		3		1	1				3
In situ RNA (whole mount)		1	1	1	1	1
Northern blot								2			1	1		3
Western blot														1
RT-PCR	1	2	2	2		1	1				3	1	1	3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Lpar2  lysophosphatidic acid receptor 2   (Synonyms: Edg4, LPA2)
Results	Reference
4*	J:69160 Contos JJ, Chun J, The mouse lp(A3)/Edg7 lysophosphatidic acid receptor gene: genomic structure, chromosomal localization, and expression pattern. Gene. 2001 Apr 18;267(2):243-53
2*	J:65882 Contos JJ, Fukushima N, Weiner JA, Kaushal D, Chun J, Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior. Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13384-9
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:160820 Dubin AE, Herr DR, Chun J, Diversity of lysophosphatidic acid receptor-mediated intracellular calcium signaling in early cortical neurogenesis. J Neurosci. 2010 May 26;30(21):7300-9
3*	J:196844 Furuta D, Yamane M, Tsujiuchi T, Moriyama R, Fukushima N, Lysophosphatidic acid induces neurite branch formation through LPA3. Mol Cell Neurosci. 2012 May;50(1):21-34
1*	J:166492 Itoh R, Miura S, Takimoto A, Kondo S, Sano H, Hiraki Y, Stimulatory actions of lysophosphatidic acid on mouse ATDC5 chondroprogenitor cells. J Bone Miner Metab. 2010 Nov;28(6):659-71
1	J:169062 Lopez-Juarez A, Morales-Lazaro S, Sanchez-Sanchez R, Sunkara M, Lomeli H, Velasco I, Morris AJ, Escalante-Alcalde D, Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development. Glia. 2011 Apr;59(4):577-89
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
2*	J:313631 McDonald WS, Miyamoto K, Rivera R, Kennedy G, Almeida BSV, Kingsbury MA, Chun J, Altered cleavage plane orientation with increased genomic aneuploidy produced by receptor-mediated lysophosphatidic acid (LPA) signaling in mouse cerebral cortical neural progenitor cells. Mol Brain. 2020 Dec 14;13(1):169
1*	J:79922 McGiffert C, Contos JJ, Friedman B, Chun J, Embryonic brain expression analysis of lysophospholipid receptor genes suggests roles for s1p(1) in neurogenesis and s1p(1-3) in angiogenesis. FEBS Lett. 2002 Oct 30;531(1):103-8
5*	J:140656 Ohuchi H, Hamada A, Matsuda H, Takagi A, Tanaka M, Aoki J, Arai H, Noji S, Expression patterns of the lysophospholipid receptor genes during mouse early development. Dev Dyn. 2008 Nov;237(11):3280-94
6*	J:276705 Suckau O, Gross I, Schrotter S, Yang F, Luo J, Wree A, Chun J, Baska D, Baumgart J, Kano K, Aoki J, Brauer AU, LPA1 , LPA2 , LPA4 , and LPA6 receptor expression during mouse brain development. Dev Dyn. 2019 May;248(5):375-395
3*	J:116891 Tanaka M, Okudaira S, Kishi Y, Ohkawa R, Iseki S, Ota M, Noji S, Yatomi Y, Aoki J, Arai H, Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid. J Biol Chem. 2006 Sep 1;281(35):25822-30
3*	J:321809 Uenaka M, Uyeda A, Nakahara T, Muramatsu R, LPA2 promotes neuronal differentiation and neurite formation in neocortical development. Biochem Biophys Res Commun. 2022 Apr 2;598:89-94
4*	J:110324 van Meeteren LA, Ruurs P, Stortelers C, Bouwman P, van Rooijen MA, Pradere JP, Pettit TR, Wakelam MJ, Saulnier-Blache JS, Mummery CL, Moolenaar WH, Jonkers J, Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development. Mol Cell Biol. 2006 Jul;26(13):5015-22
1*	J:178322 Yung YC, Mutoh T, Lin ME, Noguchi K, Rivera RR, Choi JW, Kingsbury MA, Chun J, Lysophosphatidic acid signaling may initiate fetal hydrocephalus. Sci Transl Med. 2011 Sep 7;3(99):99ra87