Gene Expression Literature Summary

• Symbol: Keap1
• Name: kelch-like ECH-associated protein 1
• ID: MGI:1858732

8 matching records from 8 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E9.5	E11.5	E13.5	E17.5	E18.5	P
Immunohistochemistry (section)								1
Immunohistochemistry (whole mount)	1	1
In situ RNA (whole mount)			1	1
In situ reporter (knock in)							1	1
Western blot					1	1	2	4
RT-PCR	1	1			1		1	3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Keap1  kelch-like ECH-associated protein 1   (Synonyms: INrf2, mKIAA0132, ring canal protein)
Results	Reference
1	J:172598 Brewer AC, Murray TV, Arno M, Zhang M, Anilkumar NP, Mann GE, Shah AM, Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo. Free Radic Biol Med. 2011 Jul 1;51(1):205-15
4	J:330375 Dionne G, Calder M, Betts DH, Rafea BA, Watson AJ, Expression and localization of NRF2/Keap1 signalling pathway genes in mouse preimplantation embryos exposed to free fatty acids. Gene Expr Patterns. 2022 Oct 13;46:119281
6	J:316639 He MY, Wang G, Han SS, Jin Y, Li H, Wu X, Ma ZL, Cheng X, Tang X, Yang X, Liu GS, Nrf2 signalling and autophagy are involved in diabetes mellitus-induced defects in the development of mouse placenta. Open Biol. 2016 Jul;6(7)
2	J:230728 Kumar V, Bouameur JE, Bar J, Rice RH, Hornig-Do HT, Roop DR, Schwarz N, Brodesser S, Thiering S, Leube RE, Wiesner RJ, Vijayaraj P, Brazel CB, Heller S, Binder H, Loffler-Wirth H, Seibel P, Magin TM, A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 7;211(5):1057-75
1	J:162676 Taguchi K, Maher JM, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M, Genetic analysis of cytoprotective functions supported by graded expression of Keap1. Mol Cell Biol. 2010 Jun;30(12):3016-26
4	J:133900 Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, Yamamoto M, Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity. Mol Cell Biol. 2008 Apr;28(8):2758-70
2*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
2	J:277277 Zieman AG, Poll BG, Ma J, Coulombe PA, Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma. Hum Mol Genet. 2019 Jul 1;28(13):2255-2270