Symbol Name ID |
Irf7
interferon regulatory factor 7 MGI:1859212 |
Age | E9.5 | E10.5 | E11.5 | E13.5 | E14.5 | E15.5 | E17 | E | P |
Immunohistochemistry (section) | 1 | ||||||||
In situ RNA (section) | 1 | 2 | |||||||
In situ RNA (whole mount) | 2 | 1 | |||||||
Northern blot | 1 | ||||||||
Western blot | 1 | ||||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 5 |
Irf7 interferon regulatory factor 7 | |
Results | Reference |
1 | J:320348 Aditi, Downing SM, Schreiner PA, Kwak YD, Li Y, Shaw TI, Russell HR, McKinnon PJ, Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair. Neuron. 2021 Dec 15;109(24):3962-3979.e6 |
1* | J:192255 Ahn J, Gutman D, Saijo S, Barber GN, STING manifests self DNA-dependent inflammatory disease. Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19386-91 |
1 | J:184926 Blackburn J, Ohazama A, Kawasaki K, Otsuka-Tanaka Y, Liu B, Honda K, Rountree RB, Hu Y, Kawasaki M, Birchmeier W, Schmidt-Ullrich R, Kinoshita A, Schutte BC, Hammond NL, Dixon MJ, Sharpe PT, The role of Irf6 in tooth epithelial invagination. Dev Biol. 2012 May 1;365(1):61-70 |
1 | J:345820 Cardarelli S, Biglietto M, Orsini T, Fustaino V, Monaco L, de Oliveira do Rego AG, Liccardo F, Masciarelli S, Fazi F, Naro F, De Angelis L, Pellegrini M, Modulation of cAMP/cGMP signaling as prevention of congenital heart defects in Pde2A deficient embryos: a matter of oxidative stress. Cell Death Dis. 2024 Feb 23;15(2):169 |
1 | J:226998 Gao D, Li T, Li XD, Chen X, Li QZ, Wight-Carter M, Chen ZJ, Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases. Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):E5699-705 |
2 | J:339248 Geng X, Zhang C, Li M, Wang J, Ji F, Feng H, Xing M, Li F, Zhang L, Li W, Chen Z, Hickson ID, Shen H, Ying S, PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS-STING-Mediated Interferon Response. Adv Sci (Weinh). 2022 Mar;9(7):e2103837 |
2* | J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1 | J:317546 Heraud-Farlow JE, Chalk AM, Linder SE, Li Q, Taylor S, White JM, Pang L, Liddicoat BJ, Gupte A, Li JB, Walkley CR, Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis. Genome Biol. 2017 Sep 5;18(1):166 |
1* | J:265968 Mannion NM, Greenwood SM, Young R, Cox S, Brindle J, Read D, Nellaker C, Vesely C, Ponting CP, McLaughlin PJ, Jantsch MF, Dorin J, Adams IR, Scadden AD, Ohman M, Keegan LP, O'Connell MA, The RNA-editing enzyme ADAR1 controls innate immune responses to RNA. Cell Rep. 2014 Nov 20;9(4):1482-94 |
1* | J:272586 Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, Yamamoto T, Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019 Feb 15;146(4):dev168146 |
1 | J:259382 Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, Arbour N, Prat A, Majewski J, Lathrop M, Vidal SM, Gros P, USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation. Nat Immunol. 2017 Jan;18(1):54-63 |
1 | J:203132 Velecela V, Lettice LA, Chau YY, Slight J, Berry RL, Thornburn A, Gunst QD, van den Hoff M, Reina M, Martinez FO, Hastie ND, Martinez-Estrada OM, WT1 regulates the expression of inhibitory chemokines during heart development. Hum Mol Genet. 2013 Dec 20;22(25):5083-95 |
1* | J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6 |
1* | J:353283 Yermalovich AV, Mohsenin Z, Cowdin M, Giotti B, Gupta A, Feng A, Golomb L, Wheeler DB, Xu K, Tsankov A, Cleaver O, Meyerson M, An essential role for Cmtr2 in mammalian embryonic development. Dev Biol. 2024 Jul 31;516:47-58 |
1* | J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48 |
1* | J:94874 Yoshida H, Okabe Y, Kawane K, Fukuyama H, Nagata S, Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA. Nat Immunol. 2005 Jan;6(1):49-56 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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