Gene Expression Literature Summary

• Symbol: Pqbp1
• Name: polyglutamine binding protein 1
• ID: MGI:1859638

6 matching records from 6 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E10.5	E11	E11.5	E12.5	E13	E13.5	E15	E15.5	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)		1		1	1		3	1		2		1	1
In situ RNA (section)		1			1		1			1			1
In situ RNA (whole mount)	1		1
Western blot	1	1			1	2	1	2	1	1	1	1	4
RT-PCR			1			1						1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pqbp1  polyglutamine binding protein 1   (Synonyms: Sfc2)
Results	Reference
3	J:279053 Ito H, Shiwaku H, Yoshida C, Homma H, Luo H, Chen X, Fujita K, Musante L, Fischer U, Frints SG, Romano C, Ikeuchi Y, Shimamura T, Imoto S, Miyano S, Muramatsu SI, Kawauchi T, Hoshino M, Sudol M, Arumughan A, Wanker EE, Rich T, Schwartz C, Matsuzaki F, Bonni A, Kalscheuer VM, Okazawa H, In utero gene therapy rescues microcephaly caused by Pqbp1-hypofunction in neural stem progenitor cells. Mol Psychiatry. 2015 Apr;20(4):459-71
2	J:204402 Li C, Ito H, Fujita K, Shiwaku H, Qi Y, Tagawa K, Tamura T, Okazawa H, Sox2 transcriptionally regulates PQBP1, an intellectual disability-microcephaly causative gene, in neural stem progenitor cells. PLoS One. 2013;8(7):e68627
10	J:334752 Liu W, Xie H, Liu X, Xu S, Cheng S, Wang Z, Xie T, Zhang ZC, Han J, PQBP1 regulates striatum development through balancing striatal progenitor proliferation and differentiation. Cell Rep. 2023 Mar 28;42(3):112277
6*	J:353600 Liu X, Xie H, Liu W, Zuo J, Li S, Tian Y, Zhao J, Bai M, Li J, Bao L, Han J, Zhang ZC, Dynamic regulation of alternative polyadenylation by PQBP1 during neurogenesis. Cell Rep. 2024 Aug 27;43(8):114525
14*	J:101560 Qi Y, Hoshino M, Wada Y, Marubuchi S, Yoshimura N, Kanazawa I, Shinomiya K, Okazawa H, PQBP-1 is expressed predominantly in the central nervous system during development. Eur J Neurosci. 2005 Sep;22(6):1277-86
2*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48