Symbol Name ID |
Arhgef7
Rho guanine nucleotide exchange factor MGI:1860493 |
Age | E5.5 | E6 | E6.5 | E7.5 | E8 | E8.5 | E10.5 | E11.5 | E13 | E14.5 | E15.5 | E16.5 | E17 | E18 | P |
Immunohistochemistry (section) | 1 | 1 | 1 | ||||||||||||
In situ RNA (section) | 1 | 1 | 1 | 1 | 1 | ||||||||||
In situ RNA (whole mount) | 1 | ||||||||||||||
In situ reporter (knock in) | 1 | 1 | 1 | 2 | 1 | 2 | |||||||||
Northern blot | 1 | 1 | 1 | ||||||||||||
Western blot | 1 | 1 | 1 | 1 | 2 | ||||||||||
RT-PCR | 1 | 1 |
Arhgef7 Rho guanine nucleotide exchange factor (Synonyms: betaPix, betaPix-b, betaPix-c, Cool, cool-1, p85SPR, Pak interacting exchange factor, PIX) | |
Results | Reference |
1* | J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034 |
1* | J:284300 Kang T, Lee SJ, Kwon Y, Park D, Loss of Pix Causes Defects in Early Embryonic Development, and Cell Spreading and PlateletDerived Growth Factor-Induced Chemotaxis in Mouse Embryonic Fibroblasts. Mol Cells. 2019 Aug 31;42(8):589-596 |
2 | J:278009 Lopez Tobon A, Suresh M, Jin J, Vitriolo A, Pietralla T, Tedford K, Bossenz M, Mahnken K, Kiefer F, Testa G, Fischer KD, Puschel AW, The guanine nucleotide exchange factor Arhgef7/betaPix promotes axon formation upstream of TC10. Sci Rep. 2018 Jun 11;8(1):8811 |
3* | J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86 |
2 | J:299536 Omelchenko T, Hall A, Anderson KV, beta-Pix-dependent cellular protrusions propel collective mesoderm migration in the mouse embryo. Nat Commun. 2020 Nov 27;11(1):6066 |
9 | J:217373 Omelchenko T, Rabadan MA, Hernandez-Martinez R, Grego-Bessa J, Anderson KV, Hall A, beta-Pix directs collective migration of anterior visceral endoderm cells in the early mouse embryo. Genes Dev. 2014 Dec 15;28(24):2764-77 |
1 | J:148808 Sawallisch C, Berhorster K, Disanza A, Mantoani S, Kintscher M, Stoenica L, Dityatev A, Sieber S, Kindler S, Morellini F, Schweizer M, Boeckers TM, Korte M, Scita G, Kreienkamp HJ, The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity. J Biol Chem. 2009 Apr 3;284(14):9225-36 |
3 | J:335681 Schlienger S, Yam PT, Balekoglu N, Ducuing H, Michaud JF, Makihara S, Kramer DK, Chen B, Fasano A, Berardelli A, Hamdan FF, Rouleau GA, Srour M, Charron F, Genetics of mirror movements identifies a multifunctional complex required for Netrin-1 guidance and lateralization of motor control. Sci Adv. 2023 May 12;9(19):eadd5501 |
2* | J:109514 Vats KR, Ishwad C, Singla I, Vats A, Ferrell R, Ellis D, Moritz M, Surti U, Jayakar P, Frederick DR, Vats AN, A locus for renal malformations including vesico-ureteric reflux on chromosome 13q33-34. J Am Soc Nephrol. 2006 Apr;17(4):1158-67 |
4* | J:84356 Yoshizawa M, Sone M, Matsuo N, Nagase T, Ohara O, Nabeshima Y, Hoshino M, Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain. Gene Expr Patterns. 2003 Jun;3(3):375-81 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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