Gene Expression Literature Summary

• Symbol: Lmbr1
• Name: limb region 1
• ID: MGI:1861746

8 matching records from 8 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E10.5	E11	E11.5	E12	E12.5	E13.5	E	P
In situ reporter (knock in)								1
Northern blot		1	1	1	1	1	1	1
RT-PCR	2	1	2			1	2	1
cDNA clones	1		2					1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Lmbr1  limb region 1   (Synonyms: 1110048D14Rik)
Results	Reference
1	J:145170 Amano T, Sagai T, Tanabe H, Mizushina Y, Nakazawa H, Shiroishi T, Chromosomal dynamics at the Shh locus: limb bud-specific differential regulation of competence and active transcription. Dev Cell. 2009 Jan;16(1):47-57
1*	J:217498 Anderson E, Devenney PS, Hill RE, Lettice LA, Mapping the Shh long-range regulatory domain. Development. 2014 Oct;141(20):3934-43
8*	J:63394 Clark RM, Marker PC, Kingsley DM, A novel candidate gene for mouse and human preaxial polydactyly with altered expression in limbs of Hemimelic extra-toes mutant mice. Genomics. 2000 Jul 1;67(1):19-27
2*	J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
3	J:97323 Niedermaier M, Schwabe GC, Fees S, Helmrich A, Brieske N, Seemann P, Hecht J, Seitz V, Stricker S, Leschik G, Schrock E, Selby PB, Mundlos S, An inversion involving the mouse Shh locus results in brachydactyly through dysregulation of Shh expression. J Clin Invest. 2005 Apr 1;115(4):900-909
3	J:87798 Sagai T, Masuya H, Tamura M, Shimizu K, Yada Y, Wakana S, Gondo Y, Noda T, Shiroishi T, Phylogenetic conservation of a limb-specific, cis-acting regulator of Sonic hedgehog ( Shh). Mamm Genome. 2004 Jan;15(1):23-34
2	J:237498 Symmons O, Pan L, Remeseiro S, Aktas T, Klein F, Huber W, Spitz F, The Shh Topological Domain Facilitates the Action of Remote Enhancers by Reducing the Effects of Genomic Distances. Dev Cell. 2016 Dec 05;39(5):529-543
1	J:284117 Williamson I, Kane L, Devenney PS, Flyamer IM, Anderson E, Kilanowski F, Hill RE, Bickmore WA, Lettice LA, Developmentally regulated Shh expression is robust to TAD perturbations. Development. 2019 Sep 30;146(19):dev179523