Gene Expression Literature Summary

• Symbol: Cdh23
• Name: cadherin related 23 (otocadherin)
• ID: MGI:1890219

18 matching records from 18 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E11	E11.5	E12.5	E13.5	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E20	E	P
Immunohistochemistry (section)				1	1	3		1		2				2			5
In situ RNA (section)			1		1	2		2					1	2			2
Immunohistochemistry (whole mount)										1		1		1			3
In situ RNA (whole mount)																	1
Western blot																	2
RT-PCR	1	1		2			1		1	1	2		1		1	1	7
cDNA clones							1										2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cdh23  cadherin related 23 (otocadherin)   (Synonyms: 4930542A03Rik, ahl, bob, mdfw, nmf112, nmf181, nmf252, sals, USH1D)
Results	Reference
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
3	J:80836 Boeda B, El-Amraoui A, Bahloul A, Goodyear R, Daviet L, Blanchard S, Perfettini I, Fath KR, Shorte S, Reiners J, Houdusse A, Legrain P, Wolfrum U, Richardson G, Petit C, Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle. EMBO J. 2002 Dec 16;21(24):6689-99
1*	J:283946 Chatterjee S, Nandakumar P, Auer DR, Gabriel SB, Chakravarti A, Gene- and tissue-level interactions in normal gastrointestinal development and Hirschsprung disease. Proc Natl Acad Sci U S A. 2019 Dec 9;
8*	J:66698 Di Palma F, Holme RH, Bryda EC, Belyantseva IA, Pellegrino R, Kachar B, Steel KP, Noben-Trauth K, Mutations in cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for usher syndrome type 1D. Nat Genet. 2001 Jan;27(1):103-7
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:212101 Kamiya K, Michel V, Giraudet F, Riederer B, Foucher I, Papal S, Perfettini I, Le Gal S, Verpy E, Xia W, Seidler U, Georgescu MM, Avan P, El-Amraoui A, Petit C, An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9307-12
6	J:98268 Lagziel A, Ahmed ZM, Schultz JM, Morell RJ, Belyantseva IA, Friedman TB, Spatiotemporal pattern and isoforms of cadherin 23 in wild type and waltzer mice during inner ear hair cell development. Dev Biol. 2005 Apr 15;280(2):295-306
4	J:263485 Lagziel A, Overlack N, Bernstein SL, Morell RJ, Wolfrum U, Friedman TB, Expression of cadherin 23 isoforms is not conserved: implications for a mouse model of Usher syndrome type 1D. Mol Vis. 2009 Sep 12;15:1843-57
4	J:135991 Lefevre G, Michel V, Weil D, Lepelletier L, Bizard E, Wolfrum U, Hardelin JP, Petit C, A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth. Development. 2008 Apr;135(8):1427-37
3*	J:151359 Lelli A, Asai Y, Forge A, Holt JR, Geleoc GS, Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea. J Neurophysiol. 2009 Jun;101(6):2961-73
6	J:244775 Libe-Philippot B, Michel V, Boutet de Monvel J, Le Gal S, Dupont T, Avan P, Metin C, Michalski N, Petit C, Auditory cortex interneuron development requires cadherins operating hair-cell mechanoelectrical transduction. Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):7765-7774
1	J:122415 Michalski N, Michel V, Bahloul A, Lefevre G, Barral J, Yagi H, Chardenoux S, Weil D, Martin P, Hardelin JP, Sato M, Petit C, Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning. J Neurosci. 2007 Jun 13;27(24):6478-88
2*	J:221671 Scheffer DI, Shen J, Corey DP, Chen ZY, Gene Expression by Mouse Inner Ear Hair Cells during Development. J Neurosci. 2015 Apr 22;35(16):6366-80
1	J:176236 Steigelman KA, Lelli A, Wu X, Gao J, Lin S, Piontek K, Wodarczyk C, Boletta A, Kim H, Qian F, Germino G, Geleoc GS, Holt JR, Zuo J, Polycystin-1 is required for stereocilia structure but not for mechanotransduction in inner ear hair cells. J Neurosci. 2011 Aug 24;31(34):12241-50
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
2	J:221167 Urness LD, Wang X, Shibata S, Ohyama T, Mansour SL, Fgf10 is required for specification of non-sensory regions of the cochlear epithelium. Dev Biol. 2015 Apr 1;400(1):59-71
5	J:69985 Wilson SM, Householder DB, Coppola V, Tessarollo L, Fritzsch B, Lee EC, Goss D, Carlson GA, Copeland NG, Jenkins NA, Mutations in Cdh23 Cause Nonsyndromic Hearing Loss in waltzer Mice. Genomics. 2001 Jun 1;74(2):228-33
3	J:308821 Zhang L, Cheng J, Zhou Q, Khan MA, Fu J, Duan C, Sun S, Lv H, Fu J, Targeted Next-Generation Sequencing Identified Novel Compound Heterozygous Variants in the CDH23 Gene Causing Usher Syndrome Type ID in a Chinese Patient. Front Genet. 2020;11:422