Symbol Name ID |
Vps35
VPS35 retromer complex component MGI:1890467 |
Age | E0.5 | E1 | E1.5 | E2 | E2.5 | E3.5 | E6.5 | E7.5 | E9.5 | E12 | E12.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E18.5 | P |
Immunohistochemistry (section) | 2 | ||||||||||||||||||
In situ reporter (knock in) | 1 | 1 | 1 | 2 | 3 | ||||||||||||||
Northern blot | 1 | 1 | 1 | 1 | 1 | ||||||||||||||
Western blot | 3 | ||||||||||||||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 5 | ||||||
cDNA clones | 1 |
Vps35 VPS35 retromer complex component (Synonyms: Mem3) | |
Results | Reference |
3* | J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998; |
14* | J:34783 Hwang S, Benjamin LE, Oh B, Rothstein JL, Ackerman SL, Beddington RSP, Solter D, Knowles BB, Genetic mapping and embryonic expression of a novel, maternally transcribed gene Mem3. Mamm Genome. 1996 Aug;7(8):586-90 |
6 | J:280216 Liu W, Tang FL, Erion J, Xiao H, Ye J, Xiong WC, Vps35 haploinsufficiency results in degenerative-like deficit in mouse retinal ganglion neurons and impairment of optic nerve injury-induced gliosis. Mol Brain. 2014 Feb 11;7:10 |
2 | J:304858 Olthof AM, White AK, Mieruszynski S, Doggett K, Lee MF, Chakroun A, Abdel Aleem AK, Rousseau J, Magnani C, Roifman CM, Campeau PM, Heath JK, Kanadia RN, Disruption of exon-bridging interactions between the minor and major spliceosomes results in alternative splicing around minor introns. Nucleic Acids Res. 2021 Apr 6;49(6):3524-3545 |
1 | J:324458 Roque M, Alves Rodrigues de Souza D, Rangel-Sosa MM, Altounian M, Hocine M, Deloulme JC, Barbier EL, Mann F, Chauvet S, VPS35 deficiency in the embryonic cortex leads to prenatal cell loss and abnormal development of axonal connectivity. Mol Cell Neurosci. 2022 Mar 31;120:103726 |
5 | J:225806 Tang FL, Erion JR, Tian Y, Liu W, Yin DM, Ye J, Tang B, Mei L, Xiong WC, VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for alpha-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease. J Neurosci. 2015 Jul 22;35(29):10613-28 |
1* | J:130260 Van Dyck F, Braem CV, Chen Z, Declercq J, Deckers R, Kim BM, Ito S, Wu MK, Cohen DE, Dewerchin M, Derua R, Waelkens E, Fiette L, Roebroek A, Schuit F, Van de Ven WJ, Shivdasani RA, Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons. Cell Metab. 2007 Nov;6(5):406-13 |
4* | J:192876 Wang CL, Tang FL, Peng Y, Shen CY, Mei L, Xiong WC, VPS35 regulates developing mouse hippocampal neuronal morphogenesis by promoting retrograde trafficking of BACE1. Biol Open. 2013;1(12):1248-1257 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 12/17/2024 MGI 6.24 |
|
|