Gene Expression Literature Summary

• Symbol: Scube1
• Name: signal peptide, CUB domain, EGF-like 1
• ID: MGI:1890616

11 matching records from 11 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E8	E8.5	E9	E9.5	E10.5	E11.5	E12.5	E13.5	E14	E14.5	E15.5	E16.5	E18.5	E	P
Immunohistochemistry (section)								1							1
In situ RNA (section)						1	1		2	1	4	2	1	1		1
In situ RNA (whole mount)	1	1	1	1	1	2	2		1			1			1
Northern blot								1								1
RT-PCR																1
cDNA clones							1	1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Scube1  signal peptide, CUB domain, EGF-like 1   (Synonyms: 7330410C13Rik, A630023E24Rik)
Results	Reference
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1	J:323616 Grimaldi A, Comai G, Mella S, Tajbakhsh S, Identification of bipotent progenitors that give rise to myogenic and connective tissues in mouse. Elife. 2022 Feb 28;11:e70235
16*	J:66050 Grimmond S, Larder R, Van Hateren N, Siggers P, Hulsebos TJ, Arkell R, Greenfield A, Cloning, mapping, and expression analysis of a gene encoding a novel mammalian EGF-related protein (SCUBE1). Genomics. 2000 Nov 15;70(1):74-81
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2*	J:226028 Lewandowski JP, Du F, Zhang S, Powell MB, Falkenstein KN, Ji H, Vokes SA, Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103
1	J:306541 Lin YC, Niceta M, Muto V, Vona B, Pagnamenta AT, Maroofian R, Beetz C, van Duyvenvoorde H, Dentici ML, Lauffer P, Vallian S, Ciolfi A, Pizzi S, Bauer P, Gruning NM, Bellacchio E, Del Fattore A, Petrini S, Shaheen R, Tiosano D, Halloun R, Pode-Shakked B, Albayrak HM, Isik E, Wit JM, Dittrich M, Freire BL, Bertola DR, Jorge AAL, Barel O, Sabir AH, Al Tenaiji AMJ, Taji SM, Al-Sannaa N, Al-Abdulwahed H, Digilio MC, Irving M, Anikster Y, Bhavani GSL, Girisha KM, Haaf T, Taylor JC, Dallapiccola B, Alkuraya FS, Yang RB, Tartaglia M, SCUBE3 loss-of-function causes a recognizable recessive developmental disorder due to defective bone morphogenetic protein signaling. Am J Hum Genet. 2021 Jan 7;108(1):115-133
1	J:335153 Qiu T, Huteckova B, Seppala M, Cobourne MT, Chen Z, Hovorakova M, Buchtova M, Tucker AS, Molecular profiling of the vestibular lamina highlights a key role for Hedgehog signalling. Development. 2023 Apr 1;150(7):dev201464
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:235538 Tomann P, Paus R, Millar SE, Scheidereit C, Schmidt-Ullrich R, Lhx2 is a direct NF-kappaB target gene that promotes primary hair follicle placode down-growth. Development. 2016 May 1;143(9):1512-22
2	J:136534 Tu CF, Yan YT, Wu SY, Djoko B, Tsai MT, Cheng CJ, Yang RB, Domain and functional analysis of a novel platelet-endothelial cell surface protein, SCUBE1. J Biol Chem. 2008 May 2;283(18):12478-88
3	J:195784 Xavier GM, Panousopoulos L, Cobourne MT, Scube3 is expressed in multiple tissues during development but is dispensable for embryonic survival in the mouse. PLoS One. 2013;8(1):e55274