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Gene Expression Literature Summary
Symbol
Name
ID
Actn4
actinin alpha 4
MGI:1890773

10 matching records from 10 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E2 E3 E3.5 E7 E9.5 E11 E11.5 E15 E15.5 E17 E17.5 P
Immunohistochemistry (section) 1 4
In situ RNA (section) 1 1
Northern blot 1 1 1 1 2
Western blot 1
RT-PCR 1 1 1 1 1 1 3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Actn4  actinin alpha 4  
Results  Reference
1J:334092 Broadway-Stringer S, Jiang H, Wadmore K, Hooper C, Douglas G, Steeples V, Azad AJ, Singer E, Reyat JS, Galatik F, Ehler E, Bennett P, Kalisch-Smith JI, Sparrow DB, Davies B, Djinovic-Carugo K, Gautel M, Watkins H, Gehmlich K, Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2. Cells. 2023 Feb 24;12(5)
3*J:119954 Cui XS, Li XY, Shen XH, Bae YJ, Kang JJ, Kim NH, Transcription profile in mouse four-cell, morula, and blastocyst: Genes implicated in compaction and blastocoel formation. Mol Reprod Dev. 2007 Feb;74(2):133-43
1J:293086 Guo B, Lyu Q, Slivano OJ, Dirkx R, Christie CK, Czyzyk J, Hezel AF, Gharavi AG, Small EM, Miano JM, Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function. J Am Soc Nephrol. 2018 Feb;29(2):416-422
1*J:142671 Kalsotra A, Xiao X, Ward AJ, Castle JC, Johnson JM, Burge CB, Cooper TA, A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart. Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20333-8
7J:83911 Kos CH, Le TC, Sinha S, Henderson JM, Kim SH, Sugimoto H, Kalluri R, Gerszten RE, Pollak MR, Mice deficient in alpha-actinin-4 have severe glomerular disease. J Clin Invest. 2003 Jun;111(11):1683-90
2J:288722 Nilsson D, Heglind M, Arani Z, Enerback S, Foxc2 is essential for podocyte function. Physiol Rep. 2019 May;7(9):e14083
2J:104891 Osafune K, Takasato M, Kispert A, Asashima M, Nishinakamura R, Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay. Development. 2006 Jan;133(1):151-61
2J:325068 Rudolf MA, Andreeva A, Kim CE, DeNovio AC, Koshar AN, Baker W, Cartagena-Rivera AX, Corwin JT, Stiffening of Circumferential F-Actin Bands Correlates With Regenerative Failure and May Act as a Biomechanical Brake in the Mammalian Inner Ear. Front Cell Neurosci. 2022;16:859882
3J:78764 Sadl V, Jin F, Yu J, Cui S, Holmyard D, Quaggin S, Barsh G, Cordes S, The mouse Kreisler (Krml1/MafB) segmentation gene is required for differentiation of glomerular visceral epithelial cells. Dev Biol. 2002 Sep 1;249(1):16-29
1J:333147 Wu T, Xu Y, Zhang L, Liang Z, Zhou X, Evans SM, Chen J, Filamin C is Essential for mammalian myocardial integrity. PLoS Genet. 2023 Jan;19(1):e1010630

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory