Symbol Name ID |
Mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase MGI:1891037 |
Age | E6.5 | E8.5 | E9 | E9.5 | E11 | E12.5 | E13 | E14.5 | E15 | E17 | P |
Immunohistochemistry (section) | 1 | 1 | |||||||||
In situ RNA (section) | 1 | ||||||||||
In situ reporter (knock in) | 1 | 1 | |||||||||
Western blot | 1 | ||||||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 4 |
Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | |
Results | Reference |
1* | J:224837 Dutchak PA, Laxman S, Estill SJ, Wang C, Wang Y, Wang Y, Bulut GB, Gao J, Huang LJ, Tu BP, Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2. Cell Rep. 2015 Jul 21;12(3):371-9 |
4* | J:121477 Elmore CL, Wu X, Leclerc D, Watson ED, Bottiglieri T, Krupenko NI, Krupenko SA, Cross JC, Rozen R, Gravel RA, Matthews RG, Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase. Mol Genet Metab. 2007 May;91(1):85-97 |
6* | J:312368 Imbard A, Schwendimann L, Lebon S, Gressens P, Blom HJ, Benoist JF, Liver and brain differential expression of one-carbon metabolism genes during ontogenesis. Sci Rep. 2021 Oct 26;11(1):21132 |
1 | J:146959 Li S, Arning E, Liu C, Vitvitsky V, Hernandez C, Banerjee R, Bottiglieri T, Lin JD, Regulation of homocysteine homeostasis through the transcriptional coactivator PGC-1alpha. Am J Physiol Endocrinol Metab. 2009 Mar;296(3):E543-8 |
1* | J:149737 Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ, The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511 |
4 | J:316777 Wilkinson AL, Menelaou K, Rakoczy J, Tan XS, Watson ED, Disruption of Folate Metabolism Causes Poor Alignment and Spacing of Mouse Conceptuses for Multiple Generations. Front Cell Dev Biol. 2021;9:723978 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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