Symbol Name ID |
Zfp423
zinc finger protein 423 MGI:1891217 |
Age | E1.5 | E2 | E2.5 | E3 | E3.5 | E4.5 | E6.5 | E7.5 | E8.5 | E9.5 | E10.5 | E11.5 | E12.5 | E14.5 | E15.5 | E16.5 | E17.5 | E18 | E18.5 | P |
Immunohistochemistry (section) | 1 | 1 | 2 | 1 | ||||||||||||||||
In situ RNA (section) | 1 | 1 | 3 | 5 | 2 | 1 | 1 | |||||||||||||
In situ RNA (whole mount) | 1 | 2 | 2 | 3 | 2 | 1 | 1 | 1 | ||||||||||||
In situ reporter (knock in) | 1 | 2 | 2 | 1 | 1 | 2 | 1 | 3 | ||||||||||||
Northern blot | 2 | |||||||||||||||||||
Western blot | 1 | 2 | ||||||||||||||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | 2 | 8 | ||||||||||
cDNA clones | 1 |
Zfp423 zinc finger protein 423 (Synonyms: ataxia1, Ebfaz, mKIAA0760, Roaz, Zfp104) | |
Results | Reference |
5* | J:114758 Alcaraz WA, Gold DA, Raponi E, Gent PM, Concepcion D, Hamilton BA, Zfp423 controls proliferation and differentiation of neural precursors in cerebellar vermis formation. Proc Natl Acad Sci U S A. 2006;103(51):19424-19429 |
1* | J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034 |
4 | J:245759 Casoni F, Croci L, Bosone C, D'Ambrosio R, Badaloni A, Gaudesi D, Barili V, Sarna JR, Tessarollo L, Cremona O, Hawkes R, Warming S, Consalez GG, Zfp423/ZNF423 regulates cell cycle progression, the mode of cell division and the DNA-damage response in Purkinje neuron progenitors. Development. 2017 Oct 15;144(20):3686-3697 |
5 | J:301038 Casoni F, Croci L, Vincenti F, Podini P, Riba M, Massimino L, Cremona O, Consalez GG, ZFP423 regulates early patterning and multiciliogenesis in the hindbrain choroid plexus. Development. 2020 Nov 30;147(22):dev190173 |
2 | J:122275 Cheng LE, Reed RR, Zfp423/OAZ participates in a developmental switch during olfactory neurogenesis. Neuron. 2007 May 24;54(4):547-57 |
6* | J:122606 Cheng LE, Zhang J, Reed RR, The transcription factor Zfp423/OAZ is required for cerebellar development and CNS midline patterning. Dev Biol. 2007 Jul 1;307(1):43-52 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
7* | J:140465 Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P, Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85 |
1 | J:158709 Gupta RK, Arany Z, Seale P, Mepani RJ, Ye L, Conroe HM, Roby YA, Kulaga H, Reed RR, Spiegelman BM, Transcriptional control of preadipocyte determination by Zfp423. Nature. 2010 Mar 25;464(7288):619-23 |
1* | J:231595 Gurdziel K, Vogt KR, Walton KD, Schneider GK, Gumucio DL, Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun. Dev Dyn. 2016 May;245(5):614-26 |
2 | J:310880 Han S, Okawa S, Wilkinson GA, Ghazale H, Adnani L, Dixit R, Tavares L, Faisal I, Brooks MJ, Cortay V, Zinyk D, Sivitilli A, Li S, Malik F, Ilnytskyy Y, Angarica VE, Gao J, Chinchalongporn V, Oproescu AM, Vasan L, Touahri Y, David LA, Raharjo E, Kim JW, Wu W, Rahmani W, Chan JA, Kovalchuk I, Attisano L, Kurrasch D, Dehay C, Swaroop A, Castro DS, Biernaskie J, Del Sol A, Schuurmans C, Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding. Neuron. 2021 Sep 15;109(18):2847-2863.e11 |
1 | J:236236 Hong CJ, Hamilton BA, Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function. PLoS Genet. 2016 Oct;12(10):e1006357 |
1 | J:250062 Li A, Ma S, Smith SM, Lee MK, Fischer A, Borok Z, Bellusci S, Li C, Minoo P, Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate. BMC Biol. 2016 Mar 16;14:19 |
1 | J:306136 Manti M, Pui HP, Edstrom S, Risal S, Lu H, Lindgren E, Ohlsson C, Jerlhag E, Benrick A, Deng Q, Stener-Victorin E, Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice. FASEB J. 2020 Nov;34(11):14440-14457 |
6* | J:166398 Masserdotti G, Badaloni A, Green YS, Croci L, Barili V, Bergamini G, Vetter ML, Consalez GG, ZFP423 coordinates Notch and bone morphogenetic protein signaling, selectively up-regulating Hes5 gene expression. J Biol Chem. 2010 Oct 1;285(40):30814-24 |
2* | J:257918 Massimino L, Flores-Garcia L, Di Stefano B, Colasante G, Icoresi-Mazzeo C, Zaghi M, Hamilton BA, Sessa A, TBR2 antagonizes retinoic acid dependent neuronal differentiation by repressing Zfp423 during corticogenesis. Dev Biol. 2018 Feb 15;434(2):231-248 |
1 | J:356509 Mo Q, Salley J, Roshan T, Baer LA, May FJ, Jaehnig EJ, Lehnig AC, Guo X, Tong Q, Nuotio-Antar AM, Shamsi F, Tseng YH, Stanford KI, Chen MH, Identification and characterization of a supraclavicular brown adipose tissue in mice. JCI Insight. 2017 Jun 2;2(11) |
1 | J:238410 Sun C, Berry WL, Olson LE, PDGFRalpha controls the balance of stromal and adipogenic cells during adipose tissue organogenesis. Development. 2017 Jan 01;144(1):83-94 |
1* | J:127119 Visel A, Carson J, Oldekamp J, Warnecke M, Jakubcakova V, Zhou X, Shaw CA, Alvarez-Bolado G, Eichele G, Regulatory pathway analysis by high-throughput in situ hybridization. PLoS Genet. 2007 Oct 19;3(10):1867-83 |
1* | J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6 |
1 | J:297623 Wang YZ, Fan H, Ji Y, Reynolds K, Gu R, Gan Q, Yamagami T, Zhao T, Hamad S, Bizen N, Takebayashi H, Chen Y, Wu S, Pleasure D, Lam K, Zhou CJ, Olig2 regulates terminal differentiation and maturation of peripheral olfactory sensory neurons. Cell Mol Life Sci. 2020 Sep;77(18):3597-3609 |
4 | J:111316 Warming S, Rachel RA, Jenkins NA, Copeland NG, Zfp423 is required for normal cerebellar development. Mol Cell Biol. 2006 Sep;26(18):6913-22 |
8* | J:89735 Warming S, Suzuki T, Yamaguchi TP, Jenkins NA, Copeland NG, Early B-cell factor-associated zinc-finger gene is a frequent target of retroviral integration in murine B-cell lymphomas. Oncogene. 2004 Apr 8;23(15):2727-31 |
4 | J:208941 Yang QY, Liang JF, Rogers CJ, Zhao JX, Zhu MJ, Du M, Maternal obesity induces epigenetic modifications to facilitate Zfp423 expression and enhance adipogenic differentiation in fetal mice. Diabetes. 2013 Nov;62(11):3727-35 |
1 | J:210623 Yeh ML, Gonda Y, Mommersteeg MT, Barber M, Ypsilanti AR, Hanashima C, Parnavelas JG, Andrews WD, Robo1 modulates proliferation and neurogenesis in the developing neocortex. J Neurosci. 2014 Apr 16;34(16):5717-31 |
3* | J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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