Gene Expression Literature Summary

• Symbol: Lrat
• Name: lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
• ID: MGI:1891259

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7.5	E8.5	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E17.5	E18.5	E	P
In situ RNA (section)									1
In situ reporter (knock in)															1
RT-PCR	1	2	2	2	2	1	3	1	4	1	1	1	1	1	7

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Lrat  lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)   (Synonyms: 1300010A18Rik)
Results	Reference
1	J:203823 Billings SE, Pierzchalski K, Butler Tjaden NE, Pang XY, Trainor PA, Kane MA, Moise AR, The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development. FASEB J. 2013 Dec;27(12):4877-89
1*	J:226844 Collin GB, Hubmacher D, Charette JR, Hicks WL, Stone L, Yu M, Naggert JK, Krebs MP, Peachey NS, Apte SS, Nishina PM, Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation. Hum Mol Genet. 2015 Dec 15;24(24):6958-74
13	J:121381 Hu P, Zhang M, Napoli JL, Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal. Biochim Biophys Acta. 2007 Apr;1770(4):694-705
1	J:172777 Kim YK, Wassef L, Chung S, Jiang H, Wyss A, Blaner WS, Quadro L, beta-Carotene and its cleavage enzyme beta-carotene-15,15'-oxygenase (CMOI) affect retinoid metabolism in developing tissues. FASEB J. 2011 May;25(5):1641-52
8*	J:132367 Kim YK, Wassef L, Hamberger L, Piantedosi R, Palczewski K, Blaner WS, Quadro L, Retinyl ester formation by lecithin: retinol acyltransferase is a key regulator of retinoid homeostasis in mouse embryogenesis. J Biol Chem. 2008 Feb 29;283(9):5611-21
1*	J:230265 Kim YK, Zuccaro MV, Costabile BK, Rodas R, Quadro L, Tissue- and sex-specific effects of beta-carotene 15,15' oxygenase (BCO1) on retinoid and lipid metabolism in adult and developing mice. Arch Biochem Biophys. 2015 Apr 15;572:11-8
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:224079 Ohana R, Weiman-Kelman B, Raviv S, Tamm ER, Pasmanik-Chor M, Rinon A, Netanely D, Shamir R, Solomon AS, Ashery-Padan R, MicroRNAs are essential for differentiation of the retinal pigmented epithelium and maturation of adjacent photoreceptors. Development. 2015 Jul 15;142(14):2487-98
1	J:154337 Touma SE, Perner S, Rubin MA, Nanus DM, Gudas LJ, Retinoid metabolism and ALDH1A2 (RALDH2) expression are altered in the transgenic adenocarcinoma mouse prostate model. Biochem Pharmacol. 2009 Nov 1;78(9):1127-38
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
2*	J:279788 Wen B, Li S, Li H, Chen Y, Ma X, Wang J, Lu F, Qu J, Hou L, Microphthalmia-associated transcription factor regulates the visual cycle genes Rlbp1 and Rdh5 in the retinal pigment epithelium. Sci Rep. 2016 Feb 15;6:21208
1	J:283063 Wu L, Belyaeva OV, Adams MK, Klyuyeva AV, Lee SA, Goggans KR, Kesterson RA, Popov KM, Kedishvili NY, Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands. J Biol Chem. 2019 Nov 8;294(45):17060-17074