Symbol Name ID |
Fgf20
fibroblast growth factor 20 MGI:1891346 |
Age | E10 | E10.5 | E11.5 | E12 | E12.5 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E17.5 | E18 | E18.5 | E | P |
Immunohistochemistry (section) | 1 | 1 | 1 | |||||||||||||||
In situ RNA (section) | 2 | 1 | 5 | 3 | 1 | 6 | 1 | 5 | 5 | 3 | 2 | 3 | ||||||
Immunohistochemistry (whole mount) | 1 | 1 | 1 | |||||||||||||||
In situ RNA (whole mount) | 1 | 2 | 2 | 5 | 5 | 1 | 3 | 1 | ||||||||||
In situ reporter (knock in) | 3 | 6 | 3 | 3 | 1 | 9 | 1 | 5 | 1 | 4 | 1 | 2 | 3 | |||||
RT-PCR | 2 | 6 | 1 | 8 | 4 | 3 | 9 | 1 | 1 | 2 | 1 | 1 | 2 | 2 | 1 | 9 |
Fgf20 fibroblast growth factor 20 | |
Results | Reference |
2 | J:224169 Al Alam D, Danopoulos S, Schall K, Sala FG, Almohazey D, Fernandez GE, Georgia S, Frey MR, Ford HR, Grikscheit T, Bellusci S, Fibroblast growth factor 10 alters the balance between goblet and Paneth cells in the adult mouse small intestine. Am J Physiol Gastrointest Liver Physiol. 2015 Apr 15;308(8):G678-90 |
7 | J:185582 Barak H, Huh SH, Chen S, Jeanpierre C, Martinovic J, Parisot M, Bole-Feysot C, Nitschke P, Salomon R, Antignac C, Ornitz DM, Kopan R, FGF9 and FGF20 Maintain the Stemness of Nephron Progenitors in Mice and Man. Dev Cell. 2012 Jun 12;22(6):1191-207 |
2 | J:208419 Basta JM, Robbins L, Kiefer SM, Dorsett D, Rauchman M, Sall1 balances self-renewal and differentiation of renal progenitor cells. Development. 2014 Mar;141(5):1047-58 |
3 | J:267642 Biggs LC, Makela OJ, Myllymaki SM, Das Roy R, Narhi K, Pispa J, Mustonen T, Mikkola ML, Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation. Elife. 2018 Jul 31;7:e36468 |
1* | J:142800 Brunskill EW, Aronow BJ, Georgas K, Rumballe B, Valerius MT, Aronow J, Kaimal V, Jegga AG, Yu J, Grimmond S, McMahon AP, Patterson LT, Little MH, Potter SS, Atlas of gene expression in the developing kidney at microanatomic resolution. (Erratum: Dev Cell 2009; 16:482). Dev Cell. 2008 Nov;15(5):781-91 |
8* | J:231094 Du W, Prochazka J, Prochazkova M, Klein OD, Expression of FGFs during early mouse tongue development. Gene Expr Patterns. 2016 Mar;20(2):81-7 |
2* | J:330213 Ebeid M, Barnas K, Zhang H, Yaghmour A, Noreikaite G, Bjork BC, PRDM16 expression and function in mammalian cochlear development. Dev Dyn. 2022 Oct;251(10):1666-1683 |
11 | J:252728 Elo T, Lindfors PH, Lan Q, Voutilainen M, Trela E, Ohlsson C, Huh SH, Ornitz DM, Poutanen M, Howard BA, Mikkola ML, Ectodysplasin target gene Fgf20 regulates mammary bud growth and ductal invasion and branching during puberty. Sci Rep. 2017 Jul 11;7(1):5049 |
4 | J:334122 Glover JD, Sudderick ZR, Shih BB, Batho-Samblas C, Charlton L, Krause AL, Anderson C, Riddell J, Balic A, Li J, Klika V, Woolley TE, Gaffney EA, Corsinotti A, Anderson RA, Johnston LJ, Brown SJ, Wang S, Chen Y, Crichton ML, Headon DJ, The developmental basis of fingerprint pattern formation and variation. Cell. 2023 Mar 2;186(5):940-956.e20 |
3* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
13* | J:314568 Haara O, Harjunmaa E, Lindfors PH, Huh SH, Fliniaux I, Aberg T, Jernvall J, Ornitz DM, Mikkola ML, Thesleff I, Ectodysplasin regulates activator-inhibitor balance in murine tooth development through Fgf20 signaling. Development. 2012 Sep;139(17):3189-99 |
1 | J:204192 Hadjab S, Franck MC, Wang Y, Sterzenbach U, Sharma A, Ernfors P, Lallemend F, A local source of FGF initiates development of the unmyelinated lineage of sensory neurons. J Neurosci. 2013 Nov 6;33(45):17656-66 |
10* | J:76230 Hajihosseini MK, Heath JK, Expression patterns of fibroblast growth factors-18 and -20 in mouse embryos is suggestive of novel roles in calvarial and limb development. Mech Dev. 2002 Apr;113(1):79-83 |
5 | J:137155 Hayashi T, Ray CA, Bermingham-McDonogh O, Fgf20 is required for sensory epithelial specification in the developing cochlea. J Neurosci. 2008 Jun 4;28(23):5991-9 |
2 | J:157252 Hiramatsu R, Harikae K, Tsunekawa N, Kurohmaru M, Matsuo I, Kanai Y, FGF signaling directs a center-to-pole expansion of tubulogenesis in mouse testis differentiation. Development. 2010 Jan;137(2):303-12 |
5* | J:139637 Hotta Y, Sasaki S, Konishi M, Kinoshita H, Kuwahara K, Nakao K, Itoh N, Fgf16 is required for cardiomyocyte proliferation in the mouse embryonic heart. Dev Dyn. 2008 Sep 24;237(10):2947-2954 |
5 | J:184501 Huh SH, Jones J, Warchol ME, Ornitz DM, Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal. PLoS Biol. 2012 Jan;10(1):e1001231 |
5 | J:193958 Huh SH, Narhi K, Lindfors PH, Haara O, Yang L, Ornitz DM, Mikkola ML, Fgf20 governs formation of primary and secondary dermal condensations in developing hair follicles. Genes Dev. 2013 Feb 15;27(4):450-8 |
1 | J:229246 Huh SH, Warchol ME, Ornitz DM, Cochlear progenitor number is controlled through mesenchymal FGF receptor signaling. Elife. 2015;4 |
2 | J:315409 Huyghe A, Van den Ackerveken P, Sacheli R, Prevot PP, Thelen N, Renauld J, Thiry M, Delacroix L, Nguyen L, Malgrange B, MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5. Cell Rep. 2015 Oct 6;13(1):31-42 |
4 | J:95803 Lavine KJ, Yu K, White AC, Zhang X, Smith C, Partanen J, Ornitz DM, Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo. Dev Cell. 2005 Jan;8(1):85-95 |
1 | J:127228 Lee JS, Yu Q, Shin JT, Sebzda E, Bertozzi C, Chen M, Mericko P, Stadtfeld M, Zhou D, Cheng L, Graf T, MacRae CA, Lepore JJ, Lo CW, Kahn ML, Klf2 is an essential regulator of vascular hemodynamic forces in vivo. Dev Cell. 2006 Dec;11(6):845-57 |
2 | J:306027 Li H, Kurtzeborn K, Kupari J, Gui Y, Siefker E, Lu B, Matlik K, Olfat S, Montano-Rodriguez AR, Huh SH, Costantini F, Andressoo JO, Kuure S, Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF. Development. 2021 May 15;148(10):dev197475 |
1 | J:316151 Lin FJ, You LR, Yu CT, Hsu WH, Tsai MJ, Tsai SY, Endocardial cushion morphogenesis and coronary vessel development require chicken ovalbumin upstream promoter-transcription factor II. Arterioscler Thromb Vasc Biol. 2012 Nov;32(11):e135-46 |
3 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
2 | J:272577 Mok KW, Saxena N, Heitman N, Grisanti L, Srivastava D, Muraro MJ, Jacob T, Sennett R, Wang Z, Su Y, Yang LM, Ma'ayan A, Ornitz DM, Kasper M, Rendl M, Dermal Condensate Niche Fate Specification Occurs Prior to Formation and Is Placode Progenitor Dependent. Dev Cell. 2019 Jan 7;48(1):32-48.e5 |
14 | J:188114 Munnamalai V, Hayashi T, Bermingham-McDonogh O, Notch prosensory effects in the Mammalian cochlea are partially mediated by fgf20. J Neurosci. 2012 Sep 12;32(37):12876-84 |
2 | J:267954 Nguyen MB, Cohen I, Kumar V, Xu Z, Bar C, Dauber-Decker KL, Tsai PC, Marangoni P, Klein OD, Hsu YC, Chen T, Mikkola ML, Ezhkova E, FGF signalling controls the specification of hair placode-derived SOX9 positive progenitors to Merkel cells. Nat Commun. 2018 Jun 13;9(1):2333 |
1 | J:190746 Osuala K, Baker CN, Nguyen HL, Martinez C, Weinshenker D, Ebert SN, Physiological and genomic consequences of adrenergic deficiency during embryonic/fetal development in mice: impact on retinoic acid metabolism. Physiol Genomics. 2012 Oct 2;44(19):934-47 |
2* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
2 | J:176344 Ratzka A, Baron O, Grothe C, FGF-2 deficiency does not influence FGF ligand and receptor expression during development of the nigrostriatal system. PLoS One. 2011;6(8):e23564 |
1 | J:168016 Reid BS, Yang H, Melvin VS, Taketo MM, Williams T, Ectodermal Wnt/beta-catenin signaling shapes the mouse face. Dev Biol. 2011 Jan 15;349(2):261-9 |
1 | J:228872 Song R, Preston G, Kidd L, Bushnell D, Sims-Lucas S, Bates CM, Yosypiv IV, Prorenin receptor is critical for nephron progenitors. Dev Biol. 2016 Jan 15;409(2):382-91 |
2 | J:119030 Spater D, Hill TP, O'sullivan RJ, Gruber M, Conner DA, Hartmann C, Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis. Development. 2006 Aug;133(15):3039-49 |
2 | J:195033 Speer AL, Al Alam D, Sala FG, Ford HR, Bellusci S, Grikscheit TC, Fibroblast growth factor 10-fibroblast growth factor receptor 2b mediated signaling is not required for adult glandular stomach homeostasis. PLoS One. 2012;7(11):e49127 |
1* | J:338194 Sulic AM, Das Roy R, Papagno V, Lan Q, Saikkonen R, Jernvall J, Thesleff I, Mikkola ML, Transcriptomic landscape of early hair follicle and epidermal development. Cell Rep. 2023 Jun 13;42(6):112643 |
2 | J:193313 Takase HM, Itoh T, Ino S, Wang T, Koji T, Akira S, Takikawa Y, Miyajima A, FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration. Genes Dev. 2013 Jan 15;27(2):169-81 |
2 | J:204446 Tateya T, Imayoshi I, Tateya I, Hamaguchi K, Torii H, Ito J, Kageyama R, Hedgehog signaling regulates prosensory cell properties during the basal-to-apical wave of hair cell differentiation in the mammalian cochlea. Development. 2013 Sep;140(18):3848-57 |
1 | J:171050 Thiagarajan RD, Georgas KM, Rumballe BA, Lesieur E, Chiu HS, Taylor D, Tang DT, Grimmond SM, Little MH, Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS One. 2011;6(2):e17286 |
1 | J:339444 Trela E, Lan Q, Myllymaki SM, Villeneuve C, Lindstrom R, Kumar V, Wickstrom SA, Mikkola ML, Cell influx and contractile actomyosin force drive mammary bud growth and invagination. J Cell Biol. 2021 Aug 2;220(8) |
3 | J:283457 Uijtdewilligen PJE, Versteeg EM, van de Westerlo EMA, van der Vlag J, Daamen WF, van Kuppevelt TH, Dynamic Expression of Genes Involved in Proteoglycan/Glycosaminoglycan Metabolism during Skin Development. Biomed Res Int. 2018;2018:9873471 |
1* | J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6 |
1 | J:185531 Wu H, Lu Y, Barik A, Joseph A, Taketo MM, Xiong WC, Mei L, beta-Catenin gain of function in muscles impairs neuromuscular junction formation. Development. 2012 Jul;139(13):2392-404 |
3* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
1 | J:277430 Yang LM, Cheah KSE, Huh SH, Ornitz DM, Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner. PLoS Genet. 2019 Jul;15(7):e1008254 |
7 | J:272387 Yang LM, Huh SH, Ornitz DM, FGF20-Expressing, Wnt-Responsive Olfactory Epithelial Progenitors Regulate Underlying Turbinate Growth to Optimize Surface Area. Dev Cell. 2018 Sep 10;46(5):564-580.e5 |
1* | J:101025 Yaylaoglu MB, Titmus A, Visel A, Alvarez-Bolado G, Thaller C, Eichele G, Comprehensive expression atlas of fibroblast growth factors and their receptors generated by a novel robotic in situ hybridization platform. Dev Dyn. 2005 Oct;234(2):371-86 |
2 | J:163662 Zhang Y, Li S, Yuan L, Tian Y, Weidenfeld J, Yang J, Liu F, Chokas AL, Morrisey EE, Foxp1 coordinates cardiomyocyte proliferation through both cell-autonomous and nonautonomous mechanisms. Genes Dev. 2010 Aug 15;24(16):1746-57 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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