Symbol Name ID |
Mov10l1
Mov10 like RISC complex RNA helicase 1 MGI:1891384 |
Age | E8 | E8.5 | E9.5 | E10 | E10.5 | E13.5 | E15.5 | E16.5 | E18 | E18.5 | P |
Immunohistochemistry (section) | 1 | 1 | 3 | ||||||||
In situ RNA (section) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | ||||
In situ RNA (whole mount) | 1 | ||||||||||
Northern blot | 1 | 1 | 2 | ||||||||
Western blot | 2 | 2 | |||||||||
RT-PCR | 2 | 1 | 7 | ||||||||
cDNA clones | 1 | 1 | 1 | 1 | |||||||
Primer Extension | 1 |
Mov10l1 Mov10 like RISC complex RNA helicase 1 (Synonyms: CHAMP, Csm) | |
Results | Reference |
1 | J:184034 De Fazio S, Bartonicek N, Di Giacomo M, Abreu-Goodger C, Sankar A, Funaya C, Antony C, Moreira PN, Enright AJ, O'Carroll D, The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements. Nature. 2011 Dec 8;480(7376):259-63 |
2 | J:161124 Frost RJ, Hamra FK, Richardson JA, Qi X, Bassel-Duby R, Olson EN, MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11847-52 |
4 | J:238224 Fu Q, Pandey RR, Leu NA, Pillai RS, Wang PJ, Mutations in the MOV10L1 ATP Hydrolysis Motif Cause piRNA Biogenesis Failure and Male Sterility in Mice. Biol Reprod. 2016 Nov 1;95(5):103 |
1 | J:292511 Gustafson EA, Seymour KA, Sigrist K, Rooij DGDE, Freiman RN, ZFP628 Is a TAF4b-Interacting Transcription Factor Required for Mouse Spermiogenesis. Mol Cell Biol. 2020 Mar 16;40(7) |
1 | J:213984 Kogo H, Tsutsumi M, Ohye T, Inagaki H, Abe T, Kurahashi H, HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes. Genes Cells. 2012 Jun;17(6):439-54 |
10* | J:69957 Liu ZP, Nakagawa O, Nakagawa M, Yanagisawa H, Passier R, Richardson JA, Srivastava D, Olson EN, CHAMP, a novel cardiac-specific helicase regulated by MEF2C. Dev Biol. 2001 Jun 15;234(2):497-509 |
1* | J:77725 Regan CP, Li W, Boucher DM, Spatz S, Su MS, Kuida K, Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9248-53 |
2 | J:194978 Reichmann J, Reddington JP, Best D, Read D, Ollinger R, Meehan RR, Adams IR, The genome-defence gene Tex19.1 suppresses LINE-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice. Hum Mol Genet. 2013 May 1;22(9):1791-806 |
1* | J:167522 Shin YH, Choi Y, Erdin SU, Yatsenko SA, Kloc M, Yang F, Wang PJ, Meistrich ML, Rajkovic A, Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis. PLoS Genet. 2010;6(11):e1001190 |
8* | J:84692 Ueyama T, Kasahara H, Ishiwata T, Yamasaki N, Izumo S, Csm, a cardiac-specific isoform of the RNA helicase Mov10l1, is regulated by Nkx2.5 in embryonic heart. J Biol Chem. 2003 Aug 1;278(31):28750-7 |
3 | J:221349 Vourekas A, Zheng K, Fu Q, Maragkakis M, Alexiou P, Ma J, Pillai RS, Mourelatos Z, Wang PJ, The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing. Genes Dev. 2015 Mar 15;29(6):617-29 |
1 | J:95388 Wang X, Merritt AJ, Seyfried J, Guo C, Papadakis ES, Finegan KG, Kayahara M, Dixon J, Boot-Handford RP, Cartwright EJ, Mayer U, Tournier C, Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathway. Mol Cell Biol. 2005 Jan;25(1):336-45 |
1* | J:296647 Wanner N, Vornweg J, Combes A, Wilson S, Plappert J, Rafflenbeul G, Puelles VG, Rahman RU, Liwinski T, Lindner S, Grahammer F, Kretz O, Wlodek ME, Romano T, Moritz KM, Boerries M, Busch H, Bonn S, Little MH, Bechtel-Walz W, Huber TB, DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation. J Am Soc Nephrol. 2019 Jan;30(1):63-78 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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