Gene Expression Literature Summary

• Symbol: Spen
• Name: spen family transcription repressor
• ID: MGI:1891706

9 matching records from 9 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9.5	E10.5	E11.5	E13.5	E14	E14.5	E15.5	E18	E18.5	P
Immunohistochemistry (section)								1		1
In situ RNA (section)			1	3		1	1		1	3
In situ RNA (whole mount)		1					1
RT-PCR				2	1			1		3
cDNA clones	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Spen  spen family transcription repressor   (Synonyms: Mint, mKIAA0929)
Results	Reference
1	J:178485 Gradus B, Alon I, Hornstein E, miRNAs control tracheal chondrocyte differentiation. Dev Biol. 2011 Dec 1;360(1):58-65
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
4*	J:103446 McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA, A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14
1*	J:268318 Miesfeld JB, Moon MS, Riesenberg AN, Contreras AN, Kovall RA, Brown NL, Rbpj direct regulation of Atoh7 transcription in the embryonic mouse retina. Sci Rep. 2018 Jul 5;8(1):10195
1	J:62777 Obata J, Yano M, Mimura H, Goto T, Nakayama R, Mibu Y, Oka C, Kawaichi M, p48 subunit of mouse PTF1 binds to RBP-Jkappa/CBF-1, the intracellular mediator of Notch signalling, and is expressed in the neural tube of early stage embryos. Genes Cells. 2001 Apr;6(4):345-60
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1*	J:119513 Tsuji M, Shinkura R, Kuroda K, Yabe D, Honjo T, Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling. Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1610-5
5	J:332871 Zhang J, Yang Z, Yan X, Duan J, Ruan B, Zhang X, Wen T, Zhang P, Liang L, Han H, RNA-binding protein SPEN controls hepatocyte maturation via regulating Hnf4alpha expression during liver development. Biochem Biophys Res Commun. 2023 Jan 29;642:128-136