Gene Expression Literature Summary

• Symbol: Ppp4c
• Name: protein phosphatase 4, catalytic subunit
• ID: MGI:1891763

9 matching records from 9 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E7	E9.5	E10.5	E11	E11.5	E12.5	E13.5	E14	E14.5	E15	E15.5	E16	E17	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)	1	1			1		1	1			1
In situ RNA (section)				1				1		1	1		1	1		1	1		1	2
Northern blot			1			1						1			1				1
Western blot	1	1					1		2		1		1			1		1		4
RT-PCR																				1
cDNA clones																				1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ppp4c  protein phosphatase 4, catalytic subunit   (Synonyms: 1110002D08Rik, PPX)
Results	Reference
4*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:354208 Dong MZ, Ouyang YC, Gao SC, Gu LJ, Guo JN, Sun SM, Wang ZB, Sun QY, Protein phosphatase 4 maintains the survival of primordial follicles by regulating autophagy in oocytes. Cell Death Dis. 2024 Sep 8;15(9):658
6	J:325537 Dong MZ, Ouyang YC, Gao SC, Ma XS, Hou Y, Schatten H, Wang ZB, Sun QY, PPP4C facilitates homologous recombination DNA repair by dephosphorylating PLK1 during early embryo development. Development. 2022 May 15;149(10):dev200351
9	J:72888 Hu MC, Shui JW, Mihindukulasuriya KA, Tan TH, Genomic structure of the mouse PP4 gene: a developmentally regulated protein phosphatase. Gene. 2001 Oct 31;278(1-2):89-99
1*	J:356269 Kalen M, Wallgard E, Asker N, Nasevicius A, Athley E, Billgren E, Larson JD, Wadman SA, Norseng E, Clark KJ, He L, Karlsson-Lindahl L, Hager AK, Weber H, Augustin H, Samuelsson T, Kemmet CK, Utesch CM, Essner JJ, Hackett PB, Hellstrom M, Combination of reverse and chemical genetic screens reveals angiogenesis inhibitors and targets. Chem Biol. 2009 Apr 24;16(4):432-41
4	J:320195 Liu B, Sun LH, Huang YF, Guo LJ, Luo LS, Protein phosphatase 2ACalpha gene knock-out results in cortical atrophy through activating hippo cascade in neuronal progenitor cells. Int J Biochem Cell Biol. 2018 Feb;95:53-62
1	J:134682 Toyo-oka K, Mori D, Yano Y, Shiota M, Iwao H, Goto H, Inagaki M, Hiraiwa N, Muramatsu M, Wynshaw-Boris A, Yoshiki A, Hirotsune S, Protein phosphatase 4 catalytic subunit regulates Cdk1 activity and microtubule organization via NDEL1 dephosphorylation. J Cell Biol. 2008 Mar 24;180(6):1133-47
10	J:201674 Xie Y, Juschke C, Esk C, Hirotsune S, Knoblich JA, The phosphatase PP4c controls spindle orientation to maintain proliferative symmetric divisions in the developing neocortex. Neuron. 2013 Jul 24;79(2):254-65