Symbol Name ID |
Ptpmt1
protein tyrosine phosphatase, mitochondrial 1 MGI:1913711 |
Age | E3.5 | E7 | E7.5 | E10 | E10.5 | E11 | E11.5 | E15 | E17 | P |
Immunohistochemistry (whole mount) | 1 | 1 | ||||||||
In situ reporter (knock in) | 1 | |||||||||
Northern blot | 1 | 1 | 1 | 1 | ||||||
RT-PCR | 1 | 1 | 2 | 1 | 1 | 3 |
Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 (Synonyms: 1110001D10Rik, 2810004N20Rik, PLIP) | |
Results | Reference |
1* | J:333714 Huynh H, Zhu S, Lee S, Bao Y, Pang J, Nguyen A, Gu Y, Chen C, Ouyang K, Evans SM, Fang X, DELE1 is protective for mitochondrial cardiomyopathy. J Mol Cell Cardiol. 2023 Feb;175:44-48 |
1* | J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9 |
9* | J:92855 Pagliarini DJ, Worby CA, Dixon JE, A PTEN-like phosphatase with a novel substrate specificity. J Biol Chem. 2004 Sep 10;279(37):38590-6 |
3* | J:178313 Shen J, Liu X, Yu WM, Liu J, Groot Nibbelink M, Guo C, Finkel T, Qu CK, A critical role of mitochondrial phosphatase ptpmt1 in embryogenesis reveals a mitochondrial metabolic stress-induced differentiation checkpoint in embryonic stem cells. Mol Cell Biol. 2011 Dec;31(24):4902-16 |
1 | J:287702 Zheng H, Yu WM, Shen J, Kang S, Hambardzumyan D, Li JY, Shen Y, Kenney AM, Chen J, Qu CK, Mitochondrial oxidation of the carbohydrate fuel is required for neural precursor/stem cell function and postnatal cerebellar development. Sci Adv. 2018 Oct;4(10):eaat2681 |
1 | J:335524 Zhu S, Nguyen A, Pang J, Zhao J, Chen Z, Liang Z, Gu Y, Huynh H, Bao Y, Lee S, Kluger Y, Ouyang K, Evans SM, Fang X, Mitochondrial Stress Induces an HRI-eIF2alpha Pathway Protective for Cardiomyopathy. Circulation. 2022 Sep 27;146(13):1028-1031 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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