Gene Expression Literature Summary

• Symbol: Cul4a
• Name: cullin 4A
• ID: MGI:1914487

10 matching records from 10 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E3	E3.5	E4	E4.5	E5	E7.5	E9.5	E15.5	E16.5	E17	P
Immunohistochemistry (section)								1	2		1	1		2
Immunohistochemistry (whole mount)					1	1	1
In situ reporter (knock in)														1
Western blot										1	1		1	3
RT-PCR	1	1	1	1	1					1			1	2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cul4a  cullin 4A   (Synonyms: 2810470J21Rik)
Results	Reference
1	J:199139 Jiang B, Zhao W, Yuan J, Qian Y, Sun W, Zou Y, Guo C, Chen B, Shao C, Gong Y, Lack of Cul4b, an E3 ubiquitin ligase component, leads to embryonic lethality and abnormal placental development. PLoS One. 2012;7(5):e37070
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
4*	J:254519 Li G, Ji T, Chen J, Fu Y, Hou L, Feng Y, Zhang T, Song T, Zhao J, Endo Y, Lin H, Cai X, Cang Y, CRL4(DCAF8) Ubiquitin Ligase Targets Histone H3K79 and Promotes H3K9 Methylation in the Liver. Cell Rep. 2017 Feb 7;18(6):1499-1511
6	J:199210 Liu L, Yin Y, Li Y, Prevedel L, Lacy EH, Ma L, Zhou P, Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis. Cell Res. 2012 Aug;22(8):1258-69
1*	J:314180 Matsuki T, Iio A, Ueda M, Tsuneura Y, Howell BW, Nakayama A, STK25 and MST3 Have Overlapping Roles to Regulate Rho GTPases during Cortical Development. J Neurosci. 2021 Oct 27;41(43):8887-8903
1	J:226978 Tateossian H, Morse S, Simon MM, Dean CH, Brown SD, Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung. Dis Model Mech. 2015 Dec 1;8(12):1531-42
2	J:184206 Tron AE, Arai T, Duda DM, Kuwabara H, Olszewski JL, Fujiwara Y, Bahamon BN, Signoretti S, Schulman BA, DeCaprio JA, The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7. Mol Cell. 2012 Apr 13;46(1):67-78
2	J:312461 Yin Y, Zhu L, Li Q, Zhou P, Ma L, Cullin4 E3 Ubiquitin Ligases Regulate Male Gonocyte Migration, Proliferation and Blood-Testis Barrier Homeostasis. Cells. 2021 Oct 13;10(10)
7	J:205485 Yu C, Zhang YL, Pan WW, Li XM, Wang ZW, Ge ZJ, Zhou JJ, Cang Y, Tong C, Sun QY, Fan HY, CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins. Science. 2013 Dec 20;342(6165):1518-21
1	J:261328 Zou J, Ma W, Li J, Littlejohn R, Zhou H, Kim IM, Fulton DJR, Chen W, Weintraub NL, Zhou J, Su H, Neddylation mediates ventricular chamber maturation through repression of Hippo signaling. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4101-E4110