Gene Expression Literature Summary

• Symbol: Kat8
• Name: K(lysine) acetyltransferase 8
• ID: MGI:1915023

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2.5	E3	E3.5	E4	E4.5	E5.5	E7.5	E9	E9.5	E10	E10.5	E11.5	E12.5	E14.5	E15.5	E17.5	E18.5	P
Immunohistochemistry (section)							1	1	1		1
In situ RNA (section)											1				1	1	1			1
Immunohistochemistry (whole mount)	1	1	1	1	1	1
In situ RNA (whole mount)											1	1		1
Northern blot															1					1
Western blot																1		1		3
RT-PCR										2			1			2			1	2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Kat8  K(lysine) acetyltransferase 8   (Synonyms: 2010203C02Rik, 5830450F21Rik, D7Ertd629e, MOF, Myst1)
Results	Reference
2	J:228714 Badeaux AI, Yang Y, Cardenas K, Vemulapalli V, Chen K, Kusewitt D, Richie E, Li W, Bedford MT, Loss of the methyl lysine effector protein PHF20 impacts the expression of genes regulated by the lysine acetyltransferase MOF. J Biol Chem. 2012 Jan 2;287(1):429-37
4	J:350446 Bi S, Huang L, Chen Y, Hu Z, Li S, Wang Y, Huang B, Zhang L, Huang Y, Dai B, Du L, Tu Z, Wang Y, Xu D, Xu X, Sun W, Kzhyshkowska J, Wang H, Chen D, Wang F, Zhang S, KAT8-mediated H4K16ac is essential for sustaining trophoblast self-renewal and proliferation via regulating CDX2. Nat Commun. 2024 Jul 3;15(1):5602
7	J:128936 Gupta A, Guerin-Peyrou TG, Sharma GG, Park C, Agarwal M, Ganju RK, Pandita S, Choi K, Sukumar S, Pandita RK, Ludwig T, Pandita TK, The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis. Mol Cell Biol. 2008 Jan;28(1):397-409
1	J:170405 Kueh AJ, Dixon MP, Voss AK, Thomas T, HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development. Mol Cell Biol. 2011 Feb;31(4):845-60
2	J:262221 Nakajima R, Okano H, Noce T, JMJD1C Exhibits Multiple Functions in Epigenetic Regulation during Spermatogenesis. PLoS One. 2016;11(9):e0163466
2*	J:291094 Sheikh BN, Guhathakurta S, Tsang TH, Schwabenland M, Renschler G, Herquel B, Bhardwaj V, Holz H, Stehle T, Bondareva O, Aizarani N, Mossad O, Kretz O, Reichardt W, Chatterjee A, Braun LJ, Thevenon J, Sartelet H, Blank T, Grun D, von Elverfeldt D, Huber TB, Vestweber D, Avilov S, Prinz M, Buescher JM, Akhtar A, Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nat Cell Biol. 2020 Jul;22(7):828-841
8*	J:121832 Thomas T, Loveland KL, Voss AK, The genes coding for the MYST family histone acetyltransferases, Tip60 and Mof, are expressed at high levels during sperm development. Gene Expr Patterns. 2007 Jun;7(6):657-65
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1	J:206774 Wolstenholme JT, Rissman EF, Bekiranov S, Sexual differentiation in the developing mouse brain: contributions of sex chromosome genes. Genes Brain Behav. 2013 Mar;12(2):166-80
3*	J:246912 Ye A, Kim H, Kim J, PEG3 control on the mammalian MSL complex. PLoS One. 2017;12(6):e0178363
1*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
1*	J:236440 You L, Yan K, Zou J, Zhao H, Bertos NR, Park M, Wang E, Yang XJ, The chromatin regulator Brpf1 regulates embryo development and cell proliferation. J Biol Chem. 2015 May 1;290(18):11349-64