Symbol Name ID |
Dgat2
diacylglycerol O-acyltransferase 2 MGI:1915050 |
Age | E1 | E3 | E8.5 | E9.5 | E12 | E12.5 | E13.5 | E14.5 | E15 | E15.5 | E16.5 | E17.5 | E18 | E18.5 | P |
In situ RNA (section) | 2 | ||||||||||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 4 | 1 | 1 | 1 | 2 | 1 | 5 | 6 |
Dgat2 diacylglycerol O-acyltransferase 2 (Synonyms: 0610010B06Rik) | |
Results | Reference |
1 | J:179687 Banks AS, Kim-Muller JY, Mastracci TL, Kofler NM, Qiang L, Haeusler RA, Jurczak MJ, Laznik D, Heinrich G, Samuel VT, Shulman GI, Papaioannou VE, Accili D, Dissociation of the glucose and lipid regulatory functions of FoxO1 by targeted knockin of acetylation-defective alleles in mice. Cell Metab. 2011 Nov 2;14(5):587-97 |
1 | J:335426 Butera A, Agostini M, Cassandri M, De Nicola F, Fanciulli M, D'Ambrosio L, Falasca L, Nardacci R, Wang L, Piacentini M, Knight RA, Jia W, Sun Q, Shi Y, Wang Y, Candi E, Melino G, ZFP750 affects the cutaneous barrier through regulating lipid metabolism. Sci Adv. 2023 Apr 28;9(17):eadg5423 |
1* | J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582 |
1* | J:210054 Dixon JL, Kim YK, Brinker A, Quadro L, Loss of beta-carotene 15,15'-oxygenase in developing mouse tissues alters esterification of retinol, cholesterol and diacylglycerols. Biochim Biophys Acta. 2014 Jan;1841(1):34-43 |
3 | J:227474 Fonseca TL, Fernandes GW, McAninch EA, Bocco BM, Abdalla SM, Ribeiro MO, Mohacsik P, Fekete C, Li D, Xing X, Wang T, Gereben B, Bianco AC, Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):14018-23 |
1 | J:147182 Golonzhka O, Liang X, Messaddeq N, Bornert JM, Campbell AL, Metzger D, Chambon P, Ganguli-Indra G, Leid M, Indra AK, Dual role of COUP-TF-interacting protein 2 in epidermal homeostasis and permeability barrier formation. J Invest Dermatol. 2009 Jun;129(6):1459-70 |
1 | J:317805 Kato A, Ito M, Sanaki T, Okuda T, Tsuchiya N, Yoshimoto R, Yukioka H, Acsl1 is essential for skin barrier function through the activation of linoleic acid and biosynthesis of omega-O-acylceramide in mice. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Feb;1867(2):159085 |
1* | J:230265 Kim YK, Zuccaro MV, Costabile BK, Rodas R, Quadro L, Tissue- and sex-specific effects of beta-carotene 15,15' oxygenase (BCO1) on retinoid and lipid metabolism in adult and developing mice. Arch Biochem Biophys. 2015 Apr 15;572:11-8 |
5* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
4 | J:340032 Paredes A, Justo-Mendez R, Jimenez-Blasco D, Nunez V, Calero I, Villalba-Orero M, Alegre-Marti A, Fischer T, Gradillas A, Sant'Anna VAR, Were F, Huang Z, Hernansanz-Agustin P, Contreras C, Martinez F, Camafeita E, Vazquez J, Ruiz-Cabello J, Area-Gomez E, Sanchez-Cabo F, Treuter E, Bolanos JP, Estebanez-Perpina E, Ruperez FJ, Barbas C, Enriquez JA, Ricote M, gamma-Linolenic acid in maternal milk drives cardiac metabolic maturation. Nature. 2023 Jun;618(7964):365-373 |
1* | J:242353 Pichery M, Huchenq A, Sandhoff R, Severino-Freire M, Zaafouri S, Opalka L, Levade T, Soldan V, Bertrand-Michel J, Lhuillier E, Serre G, Maruani A, Mazereeuw-Hautier J, Jonca N, PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier. Hum Mol Genet. 2017 May 15;26(10):1787-1800 |
1 | J:208504 Qiao L, Yoo HS, Madon A, Kinney B, Hay WW Jr, Shao J, Adiponectin enhances mouse fetal fat deposition. Diabetes. 2012 Dec;61(12):3199-207 |
1* | J:259970 Segerer G, Hadamek K, Zundler M, Fekete A, Seifried A, Mueller MJ, Koentgen F, Gessler M, Jeanclos E, Gohla A, An essential developmental function for murine phosphoglycolate phosphatase in safeguarding cell proliferation. Sci Rep. 2016 Oct 12;6:35160 |
4* | J:88742 Stone SJ, Myers HM, Watkins SM, Brown BE, Feingold KR, Elias PM, Farese RV Jr, Lipopenia and skin barrier abnormalities in DGAT2-deficient mice. J Biol Chem. 2004 Mar 19;279(12):11767-76 |
1* | J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6 |
3 | J:348785 Zhang D, Deng W, Jiang T, Zhao Y, Bai D, Tian Y, Kong S, Zhang L, Wang H, Gao S, Lu Z, Maternal Ezh1/2 deficiency impairs the function of mitochondria in mouse oocytes and early embryos. J Cell Physiol. 2024 Mar 26; |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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